Results 181 to 190 of about 130,911 (332)

Forcing the Side‐on π‐Coordination of a C≡C Triple Bond to Technetium Using the As,CC,As Alkyne Pincer Ligand 1,2‐Bis(2‐(diisopropylarsaneyl)‐4‐(trifluoromethyl)phenyl)Ethyne

Angewandte Chemie International Edition, EarlyView.
Technetium alkyne complexes have eluded isolation for decades with the only indicators for their existence being the isolation of vinylidene carbenes or their follow‐up reaction products despite plentiful of reports for neighboring elements. Stable, crystalline Tc(III) and Tc(V) alkyne complexes (and their Re analogs) have now been prepared and fully ...
Maximilian Roca Jungfer, Moritz Johannes Ernst, Lukas Eberle, Marius Kesselring, Guilhem Claude, Joachim Ballmann   +5 more
wiley   +1 more source

A consideration of PPAR-γ ligands with respect to lipophilicity: Current trends and perspectives

, 2007
The fact that PPAR-γ is expressed dramatically higher in fat, regulating gene transcription in response to small lipophilic ligands, supports an essential role of increased lipophilicity for those ligands.
Tsantili-Kakoulidou, A., Giaginis, C., Theocharis, S.   +2 more
core  

Negatively Charged Pronucleotides as Inhibitors of Glioma Cell Proliferation. [PDF]

ACS Med Chem Lett
Romanowska J, Wawrzyniak D, Szymanska-Michalak A, Framski G, Pawlowicz-Perczak A, Sobkowski M, Stawinski J, Rolle K, Kraszewski A.   +8 more
europepmc   +1 more source

High-throughput PBK modelling for dermal exposure: a pragmatic approach to predict systemic pharmacokinetics. [PDF]

Arch Toxicol
Edizcan Z, Schaller S, Kuepfer L, Geci R.   +3 more
europepmc   +1 more source

Fungal <i>Cordyceps</i> Nucleosides and Analogs as Potential Anti-Glioblastoma PD-L1 Inhibitors: An In Silico Multiparameter Optimization (MPO) Design. [PDF]

Int J Mol Sci
Muñoz-González F, Bello M, Correa-Basurto J, Bandala C.   +3 more
europepmc   +1 more source

Novel Cinnamaldehyde Hydrazones: Design, In Silico Evaluation, Synthesis, and Cytotoxic Activity. [PDF]

Molecules
Nikolova-Mladenova B, Mihaylova R, Atanasova M.   +2 more
europepmc   +1 more source

Degradation Mechanisms, Encapsulation‐Based Stabilization, and Analytical Detection of Vitamin A

Journal of the American Oil Chemists' Society, EarlyView.
ABSTRACT Vitamin A is an important lipid‐soluble micronutrient essential for vision, immune function, and overall growth and development. However, vitamin A is unstable and susceptible to environmental factors because of its conjugated structure and inherent chemical reactivity.
Latheesha Abeywardana, Thambaramala V. Gamage, Tanoj K. Singh, Shuaifei Zhao, Amy Logan, Lingxue Kong   +5 more
wiley   +1 more source

Phosphoramidate Derivatives of Betulin, New Molecules with Promising Biological Activity: Synthesis and Characterization. [PDF]

Molecules
Chrobak E, Świtalska M, Madej M, Wietrzyk J, Bębenek E.   +4 more
europepmc   +1 more source

Preparation and Performance Evaluation of a Self‐Generated Particle Plugging Agent Based on Thermosetting Resin

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT A thermosetting in situ curing resin microsphere system has been developed. It has controllable phase transition time and particle size. This system addresses the current challenges of low strength, shear susceptibility, and short phase transition time in polymer microsphere blockers and thermoplastic particle blockers.
Baolei Jiao, Lifeng Chen, Minghao Xue, Xuemin Yan, Jiamin Zhang, Feifan Liu   +5 more
wiley   +1 more source

Structural insights into the binding mode of the hypnotic drug vornorexant to orexin receptors. [PDF]

Acta Crystallogr F Struct Biol Commun
Mima M, Mishima-Tsumagari C, Sakata-Sakuta M, Iwaoka R, Iwamoto K.   +4 more
europepmc   +1 more source