Results 211 to 220 of about 47,589 (249)
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GLYCOSYLTRANSFERASES OF LIPOPHILIC SMALL MOLECULES
Annual Review of Plant Biology, 2006Glycosyltransferases of small molecules transfer sugars to a wide range of acceptors, from hormones and secondary metabolites to biotic and abiotic chemicals and toxins in the environment. The enzymes are encoded by large multigene families and can be identified by a signature motif in their primary sequence, which classifies them as a subset of ...
Bowles, Dianna J +3 more
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Phenolic Acids Enzymatic Lipophilization
Journal of Agricultural and Food Chemistry, 2005Lipophilization is the esterification of a lipophilic moiety (fatty acid or fatty alcohol) on different substrates (phenolic acid, sugar, protein, ...), resulting in new molecules with modified hydrophilic/lipophilic balance. This reaction can be obtained chemically or enzymatically using different enzymes. Phenolic acids possess interesting biological
Figueroa-Espinoza, Maria-Cruz +1 more
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Lipases in lipophilization reactions
Biotechnology Advances, 2007Lipases are used in various sectors, as pharmaceutical, food or detergency industry. Their advantage versus classical chemical catalysts is that they exhibit a better selectivity and operate in milder reaction conditions. Theses enzymes can also be used in lipophilization reactions corresponding to the grafting of a lipophilic moiety to a hydrophilic ...
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Mechanism of Ocular Penetration of Lipophilic Drugs from Lipophilic Vehicles
Journal of Pharmaceutical SciencesSince eyedrops have conventionally been formulated in aqueous vehicles, ocular pharmacokinetic studies are generally performed using aqueous buffers to identify physicochemical properties of the drug and the vehicles that influence drug absorption. In recent years, biocompatible lipophilic vehicles are increasingly finding application in ocular drug ...
Carmen Liu +3 more
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Lipophilicity and drug activity
1979The understanding of drug potency in biological systems requires an understanding of chemical structures in terms of physical and chemical properties: transport and distribution of a drug in a biological multicompartment system, the affinity of the drug to a complementary — structurally unknown — receptor, and the interaction of the drug with its ...
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Lipophilicity Modulations by Fluorination Correlate with Membrane Partitioning
Angewandte Chemie - International Edition, 2023Bruno Linclau, Philip T F Williamson
exaly
Study of Lipophilicity and ADME Properties of 1,9-Diazaphenothiazines with Anticancer Action
International Journal of Molecular Sciences, 2023Beata Morak-Młodawska +2 more
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Lipophilicity Profiles of Ampholytes
Chemical Reviews, 1997Pagliara, Alessandra +4 more
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