Results 1 to 10 of about 518,951 (238)

Oral, nasal and pharyngeal exposure to lipopolysaccharide causes a fetal inflammatory response in sheep. [PDF]

, 2015
BackgroundA fetal inflammatory response (FIR) in sheep can be induced by intraamniotic or selective exposure of the fetal lung or gut to lipopolysaccharide (LPS).
Jobe, Alan H, Kallapur, Suhas G, Kannan, Paranthaman Senthamarai, Kemp, Matthew W, Kramer, Boris W, Maneenil, Gunlawadee, Newnham, John P, Saito, Masatoshi   +7 more
core   +12 more sources

Lipopolysaccharide Endotoxins [PDF]

Annual Review of Biochemistry, 2002
▪ Abstract  Bacterial lipopolysaccharides (LPS) typically consist of a hydrophobic domain known as lipid A (or endotoxin), a nonrepeating “core” oligosaccharide, and a distal polysaccharide (or O-antigen). Recent genomic data have facilitated study of LPS assembly in diverse Gram-negative bacteria, many of which are human or plant pathogens, and have ...
Christian R H, Raetz, Chris, Whitfield
openaire   +2 more sources

Nonmuscle Myosin Heavy Chain ⅡA-Mediated Exosome Release via Regulation of the Rho-Associated Kinase 1/Myosin Light Chains/Actin Pathway

Frontiers in Pharmacology, 2020
Nonmuscle myosin ⅡA, a kind of ATP-dependent molecular motor, binds actin to form the molecular motors of the cell. We found that interfering with nonmuscle myosin heavy chain (NMMHC) ⅡA could affect the exosome release from microglial cells stimulated ...
Yanni Lv, Jin Chen, Jinfang Hu, Yisong Qian, Ying Kong, Longsheng Fu   +5 more
doaj   +1 more source

LPS inhibits arginase-1 expression in macrophages by up-regulating activity of cytochrome P450 1A1 epoxidase

陆军军医大学学报, 2023
Objective To explore the regulative effect and mechanism of cytochrome P450 1A1 (CYP1A1) on regulating lipopolysaccharide (LPS)-induced arginase-1 (Arg-1) expression in macrophages. Methods After mouse macrophage-like cell line RAW264.7 (RAW) was treated
TIAN Lixing, ZHU Junyu, WAN Linghui, LIANG Huaping   +3 more
doaj   +1 more source

Effects of Dietary Ferulic Acid Supplementation on Hepatic Injuries in Tianfu Broilers Challenged with Lipopolysaccharide

Toxins, 2022
Lipopolysaccharide (LPS) is an endotoxin that can cause an imbalance between the oxidation and antioxidant defense systems and then induces hepatic damages.
Gang Shu, Ziting Tang, Hong Du, Yilei Zheng, Lijen Chang, Haohuan Li, Funeng Xu, Hualin Fu, Wei Zhang, Juchun Lin   +9 more
doaj   +1 more source

Aripiprazole Attenuates Cognitive Impairments Induced by Lipopolysaccharide in Rats through the Regulation of Neuronal Inflammation, Oxidative Stress, and Apoptosis

Medicina, 2023
Background and Objectives: Aripiprazole (APZ), an atypical antipsychotic, is mainly prescribed for conditions such as schizophrenia and bipolar disorder, while ongoing research indicates promising neuroprotective qualities.
Vasudevan Mani, Bander Shehail Alshammeri   +1 more
doaj   +1 more source

Effects of Dietary Ferulic Acid on Intestinal Health and Ileal Microbiota of Tianfu Broilers Challenged with Lipopolysaccharide

Molecules, 2023
Lipopolysaccharide (LPS) has been considered the primary agent to establish animal models of inflammation, immunological stress, and organ injury. Previous studies have demonstrated that LPS impaired gastrointestinal development and disrupted intestinal ...
Ziting Tang, Gang Shu, Hong Du, Yilei Zheng, Hualin Fu, Wei Zhang, Cheng Lv, Funeng Xu, Haohuan Li, Ping Ouyang, Juchun Lin, Li-Jen Chang, Felix Kwame Amevor, Xiaoling Zhao   +13 more
doaj   +1 more source

Pathological and Therapeutic Approach to Endotoxin-Secreting Bacteria Involved in Periodontal Disease

Toxins, 2021
It is widely recognized that periodontal disease is an inflammatory entity of infectious origin, in which the immune activation of the host leads to the destruction of the supporting tissues of the tooth.
Rosalia Marcano, M. Ángeles Rojo, Damián Cordoba-Diaz, Manuel Garrosa   +3 more
doaj   +1 more source

Lipopolysaccharide-specific acyloxyacyl hydrolase [PDF]

, 1991
" An acyloxyacyl hydrolase from the human promyelocyte cell line HL-60 has been found to specifically hydrolyze fatty acids from their ester linkages to hydroxy groups of 3-hydroxyfatty acids, the latter being being bound in turn to lipopolysaccharide ...
Hall, Catherine L., Munford, Robert S.
core   +1 more source

Lipopolysaccharide antagonists

Immunology Today, 1992
Bacterial lipopolysaccharide (LPS) is a potent and pleiotropic stimulus of immune cells. LPS has important clinical relevance because it has a direct role in the pathogenesis of Gram-negative bacterial infection. The lipid A moiety of LPS is responsible for the toxic effects of LPS.
W A, Lynn, D T, Golenbock
openaire   +2 more sources