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Lipopolysaccharide Endotoxins [PDF]

open access: yesAnnual Review of Biochemistry, 2002
▪ Abstract  Bacterial lipopolysaccharides (LPS) typically consist of a hydrophobic domain known as lipid A (or endotoxin), a nonrepeating “core” oligosaccharide, and a distal polysaccharide (or O-antigen). Recent genomic data have facilitated study of LPS assembly in diverse Gram-negative bacteria, many of which are human or plant pathogens, and have ...
Christian R H, Raetz, Chris, Whitfield
openaire   +3 more sources

Low-dose lipopolysaccharide as an immune regulator for homeostasis maintenance in the central nervous system through transformation to neuroprotective microglia

open access: yesNeural Regeneration Research, 2021
Microglia, which are tissue-resident macrophages in the brain, play a central role in the brain innate immunity and contribute to the maintenance of brain homeostasis. Lipopolysaccharide is a component of the outer membrane of gram-negative bacteria, and
Haruka Mizobuchi, Gen-Ichiro Soma
doaj   +2 more sources

Nanomaterials for Biosensing Lipopolysaccharide [PDF]

open access: yesBiosensors, 2019
Lipopolysaccharides (LPS) are endotoxins, hazardous and toxic inflammatory stimulators released from the outer membrane of Gram-negative bacteria, and are the major cause of septic shock giving rise to millions of fatal illnesses worldwide. There is an urgent need to identify and detect these molecules selectively and rapidly.
Keith J. Stine   +2 more
openaire   +4 more sources

Amino Compounds in Lipopolysaccharides [PDF]

open access: hybridJournal of Biological Chemistry, 1960
Henry Tauber, Harold Russell
openalex   +3 more sources

Oral, nasal and pharyngeal exposure to lipopolysaccharide causes a fetal inflammatory response in sheep. [PDF]

open access: yes, 2015
BackgroundA fetal inflammatory response (FIR) in sheep can be induced by intraamniotic or selective exposure of the fetal lung or gut to lipopolysaccharide (LPS).
Jobe, Alan H   +7 more
core   +15 more sources

Nanocurcumine Ameliorates Lipopolysaccharide-induced Depressive-like Behavior in Mice [PDF]

open access: yesNanomedicine Research Journal, 2018
Objective(s): Curcumin, a plant alkaloid from Curcuma longa, possess antioxidant and anti-inflammatory properties. Recently, the antidepressant activities of curcumin were reported. Nevertheless, bioavailability of curcumin limits its therapeutic utility.
Nahid Fakhraei   +4 more
doaj   +1 more source

Nonmuscle Myosin Heavy Chain ⅡA-Mediated Exosome Release via Regulation of the Rho-Associated Kinase 1/Myosin Light Chains/Actin Pathway

open access: yesFrontiers in Pharmacology, 2020
Nonmuscle myosin ⅡA, a kind of ATP-dependent molecular motor, binds actin to form the molecular motors of the cell. We found that interfering with nonmuscle myosin heavy chain (NMMHC) ⅡA could affect the exosome release from microglial cells stimulated ...
Yanni Lv   +5 more
doaj   +1 more source

Lipopolysaccharide-specific acyloxyacyl hydrolase [PDF]

open access: yes, 1991
" An acyloxyacyl hydrolase from the human promyelocyte cell line HL-60 has been found to specifically hydrolyze fatty acids from their ester linkages to hydroxy groups of 3-hydroxyfatty acids, the latter being being bound in turn to lipopolysaccharide ...
Hall, Catherine L., Munford, Robert S.
core   +1 more source

Placental-mediated increased cytokine response to lipopolysaccharides: a potential mechanism for enhanced inflammation susceptibility of the preterm fetus. [PDF]

open access: yes, 2012
BackgroundCerebral palsy is a nonprogressive motor impairment syndrome that has no effective cure. The etiology of most cases of cerebral palsy remains unknown; however, recent epidemiologic data have demonstrated an association between fetal neurologic ...
Belkacemi, Louiza   +4 more
core   +1 more source

Correlation of Lipopolysaccharide Endotoxin Level in Cotton Dust with the Increase of TNFα Level and the Decline of Lung Function in Cotton Spinning Factory Workers [PDF]

open access: yes, 2014
Lipopolysaccharide (LPS) endotoxin contained in cotton dust may cause airway inflammation and decline of lung function when inhaled, which eventually leads to respiratory symptoms.
Indahwati, L. (Leli)   +2 more
core   +2 more sources

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