Results 61 to 70 of about 640,235 (385)

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

FEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan, Victoria Scarpelli, Marten Exterkate   +2 more
wiley   +1 more source

Protective effects of Dioscin against sepsis‐induced cardiomyopathy via regulation of toll‐like receptor 4/MyD88/p65 signal pathway

Immunity, Inflammation and Disease
Background Dioscin has many pharmacological effects; however, its role in sepsis‐induced cardiomyopathy (SIC) is unknown. Accordingly, we concentrate on elucidating the mechanism of Dioscin in SIC rat model.
Meng Zhang, Deyuan Zhi, Pei Liu, Yajun Wang, Meili Duan   +4 more
doaj   +1 more source

Comparative Analysis of the Bioactivity and Anti-Inflammatory Effects Against Endotoxin in Mitochondria for Transplantation: Impact of Muscle Origin in Rats

Frontiers in Bioscience-Landmark
Background: Mitochondria are essential for cellular energy production and cell survival. Mitochondrial dysfunction has been implicated in various neurological disorders, prompting the development of novel therapeutic approaches ...
Da-Wei Huang, Heng-Juei Hsu, Pei-Wen Chen, Ming-Tse Wu, Chia-En Wong, Chi-Chen Huang, Po-Hsuan Lee, Hui-Fang Chen, Jung-Shun Lee   +8 more
doaj   +1 more source

Effects of Salvia miltiorrhiza ethanolic extract on lipopolysaccharide-induced dental alveolar bone resorption in rats

Journal of Dental Sciences, 2016
Background/purpose: Salvia miltiorrhiza (SM) Bunge (Labiatae/Lamiaceae; common name danshen) is a Chinese medicine that improves blood circulation and inhibits inflammatory response. Thus, it is used for the treatment of cardiac diseases and inflammation.
Huang-Tzu Tsai, Wen-Liang Chang, Hsiao-Pei Tu, Earl Fu, Yao-Dung Hsieh, Cheng-Yang Chiang   +5 more
doaj   +1 more source

RomA, A Periplasmic Protein Involved in the Synthesis of the Lipopolysaccharide, Tunes Down the Inflammatory Response Triggered by Brucella [PDF]

, 2018
Brucellaceae are stealthy pathogens with the ability to survive and replicate in the host in the context of a strong immune response. This capacity relies on several virulence factors that are able to modulate the immune system and in their structural ...
Altabe, Silvia Graciela, Casabuono, Adriana Cristina, Cassataro, Juliana, Couto, Alicia Susana, Czibener, Cecilia, Fulgenzi, Fabiana Rosa, Guaimas, Francisco Fernando, Pasquevich, Karina Alejandra, Spera, Juan Manuel, Ugalde, Juan Esteban, Valguarnera, Pablo Ezequiel   +10 more
core   +1 more source

Kaptive Web: User-Friendly Capsule and Lipopolysaccharide Serotype Prediction for Klebsiella Genomes

Journal of Clinical Microbiology, 2018
As whole-genome sequencing becomes an established component of the microbiologist's toolbox, it is imperative that researchers, clinical microbiologists, and public health professionals have access to genomic analysis tools for the rapid extraction of ...
R. Wick, E. Heinz, K. Holt, K. Wyres
semanticscholar   +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

FEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

5-deoxy-rutaecarpine protects against LPS-induced acute lung injury via inhibiting NLRP3 inflammasome-related inflammation

Frontiers in Pharmacology
IntroductionAcute lung injury (ALI) induced by lipopolysaccharide (LPS) is a significant medical condition characterized by severe pulmonary inflammation and tissue damage.
Jinque Luo, Jinque Luo, Xin Li, Xin Li, Li Zhang, Li Zhang, Meijing Deng, Jieyang Zhao, Jinghuan Zhang, Wenyu Tang, Qinghua Guo, Ling Wang   +11 more
doaj   +1 more source

Intracellular and Extracellular Lipopolysaccharide Signaling in Sepsis: Avenues for Novel Therapeutic Strategies

Journal of Innate Immunity, 2021
Sepsis is defined as organ dysfunction due to a dysregulated systemic host response to infection. During gram-negative bacterial infection and other acute illness such as absorption from the gut infection, lipopolysaccharide (LPS) is a major mediator in ...
Ramy S. Gabarin, Manshu Li, Paige A. Zimmel, John C. Marshall, Yimin Li, Haibo Zhang   +5 more
doaj   +1 more source

Toll-like receptor-mediated signaling cascade as a regulator of the inflammation network during alcoholic liver disease [PDF]

, 2014
Chronic abuse of alcohol leads to various histological abnormalities in the liver. These are conditions collectively known as alcoholic liver disease (ALD). Currently, ALD is considered to be one of the major causes of death worldwide.
Alisi, A., Ceccarelli, S, Nobili, V
core   +1 more source