Results 51 to 60 of about 351,832 (297)

In Vivo Effects of Lipopolysaccharide on Peroxisome Proliferator-Activated Receptor Expression in Juvenile Gilthead Seabream (Sparus Aurata)

open access: yesBiology, 2017
Fish are constantly exposed to microorganisms in the aquatic environment, many of which are bacterial pathogens. Bacterial pathogens activate the innate immune response in fish involving the production of pro-inflammatory molecules that, in addition to ...
Efthimia Antonopoulou   +6 more
doaj   +1 more source

Lipopolysaccharide Downregulates CD163 Expression to Inhibit PRRSV Infection via TLR4-NF-κB Pathway

open access: yesFrontiers in Microbiology, 2020
Porcine reproductive and respiratory syndrome virus (PRRSV) has been recognized to induce proinflammatory cytokine production and modulate the host interferon (IFN) system.
Zhenbang Zhu   +8 more
doaj   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

open access: yesFEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo   +4 more
wiley   +1 more source

Humoral immunity to adhesins and toxins of the pertussis pathogen in mice immunized with experimental acellular pertussis vaccines from biofilm and planktonic cultures of Bordetella pertussis

open access: yesЖурнал микробиологии, эпидемиологии и иммунобиологии
Introduction. Whooping cough remains an urgent health problem worldwide, including in countries with high vaccination rates, where, since the 1990s, there has been an increase in the incidence of whooping cough, an increase in the severity of the disease
Evgeny M. Zaitsev   +3 more
doaj   +1 more source

Piper betle L. Leaves Extract Potentially Reduce the Nitric Oxide Production on LPS-Induced RAW 264.7 Cell Lines

open access: yesJournal of Experimental Life Science, 2023
Chronic inflammation can lead to several diseases that represent the leading causes of mortality worldwide. Conventional treatment of inflammation can carry some risks. Therefore, research on herbal medicine that are suspected of having anti-inflammatory
Dinia Rizqi Dwijayanti   +2 more
doaj   +1 more source

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers   +7 more
wiley   +1 more source

Silence of MEG3 intensifies lipopolysaccharide-stimulated damage of human lung cells through modulating miR-4262

open access: yesArtificial Cells, Nanomedicine, and Biotechnology, 2019
Acute lung injury (ALI) is a serious threat for health and lives worldwide. Recently, lncRNA MEG3 has been well studied to participate in lung cancer, making us speculate that it may be essential for ALI.
Xiaoliang Li   +2 more
doaj   +1 more source

LIPOPOLYSACCHARIDE INHIBITS AUTOPHAGY IN HUMAN DERMAL FIBROBLASTS IN VITRO

open access: yesSabiad, 2022
Objective: Fibroblasts are mesenchymal cells of dermal origin that provide structural integrity for connective tissue by producing the extracellular matrix proteins.
Keyvan Hemmatvand   +2 more
doaj   +1 more source

The Gut–Heart Axis in Systemic Sclerosis: Evidence From a Large Prospective Early Disease Cohort

open access: yesArthritis Care &Research, EarlyView.
Objective Cardiac involvement significantly impacts prognosis in systemic sclerosis (SSc), highlighting the need for early risk stratification. Gastrointestinal (GI) symptoms are common and often manifest early. Emerging data suggest a link between GI and cardiac manifestations, possibly through shared mechanisms like dysautonomia.
Francesca R. Di Ciommo   +9 more
wiley   +1 more source

Escherichia coli Group 2 capsules and their interplay with bacteriophages

open access: yesFrontiers in Microbiology
IntroductionExtracellular polysaccharide capsules of Gram-negative bacteria, such as Escherichia coli (E. coli), mediate interactions with host defences and bacteriophages (phages).
Naoise McGarry   +2 more
doaj   +1 more source

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