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Lipoproteins and Atherosclerosis [PDF]

open access: greenJournal of Gerontology, 1951
Author(s): Gofman, John W.; Lindgren, Frank T.; Jones, Hardin B.; Lyon, Thomas P.; Strisower, Beverly.
John W. Gofman   +4 more
openalex   +5 more sources

IMMUNOCHEMICAL STUDIES ON HUMAN PLASMA LIPOPROTEINS [PDF]

open access: bronze, 1957
Some years ago, a series of human serum lipoproteins, distinguishable by their hydrated densities and lipid-protein ratios were recognized and isolated by ultracentrifugal techniques (1).
Frederick Aladjem   +2 more
openalex   +4 more sources

Lipoprotein(a) [PDF]

open access: yesMMW - Fortschritte der Medizin, 2021
AbstractLipoprotein(a) [Lp(a)] is an atherogenic lipoprotein with a strong genetic regulation. Up to 90% of the concentrations are explained by a single gene, theLPAgene. The concentrations show a several-hundred-fold interindividual variability ranging from less than 0.1 mg/dL to more than 300 mg/dL. Lp(a) plasma concentrations above 30 mg/dL and even
openaire   +4 more sources

Lipoprotein (a): Recent Updates on a Unique Lipoprotein [PDF]

open access: yesCurrent Atherosclerosis Reports, 2021
Genetic, epidemiological, and translational data indicate that Lipoprotein (a) [Lp(a)] is likely in the causal pathway for atherosclerotic cardiovascular diseases as well as calcification of the aortic valves.Lp(a) is structurally similar to low-density lipoprotein, but in addition to apolipoprotein B-100, it has a glycoprotein apolipoprotein(a) [apo(a)
Salim S. Virani   +4 more
openaire   +2 more sources

Alterations of intestinal lipoprotein metabolism in diabetes mellitus and metabolic syndrome [PDF]

open access: yes, 2015
Diabetes and metabolic syndrome are associated with abnormal postprandial lipoprotein metabolism, with a significant delay in the clearance of many lipid parameters, including triglycerides and chylomicrons.
ARCA, Marcello
core   +1 more source

An integrated mathematical model of cellular cholesterol biosynthesis and lipoprotein metabolism [PDF]

open access: yes, 2018
Cholesterol regulation is an important aspect of human health. In this work we bring together and extend two recent mathematical models describing cholesterol biosynthesis and lipoprotein endocytosis to create an integrated model of lipoprotein ...
Pool, Frances   +2 more
core   +2 more sources

Coronary artery endothelial dysfunction is positively correlated with low density lipoprotein and inversely correlated with high density lipoprotein subclass particles measured by nuclear magnetic resonance spectroscopy. [PDF]

open access: yes, 2009
OBJECTIVE: The association between cholesterol and endothelial dysfunction remains controversial. We tested the hypothesis that lipoprotein subclasses are associated with coronary endothelial dysfunction.
Abhiram Prasad   +42 more
core   +1 more source

Influence of different fat emulsions with 10 or 20% MCT/LCT or LCT on lipoproteins in plasma of patients after abdominal surgery [PDF]

open access: yes, 1998
In patients after elective abdominal surgery, different fat emulsions were used to compare their efficacy in total parenteral nutrition and in normalizing plasma lipoprotein levels.
Hailer, Susanne   +2 more
core   +1 more source

Relations between lipoprotein(a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic association study [PDF]

open access: yes, 2017
Background: Lipoprotein(a) concentrations in plasma are associated with cardiovascular risk in the general population. Whether lipoprotein(a) concentrations or LPA genetic variants predict long-term mortality in patients with established coronary ...
Allayee, Hooman   +103 more
core   +1 more source

Causal relevance of blood lipid fractions in the development of carotid atherosclerosis: Mendelian randomization analysis. [PDF]

open access: yes, 2013
BACKGROUND: Carotid intima-media thickness (CIMT), a subclinical measure of atherosclerosis, is associated with risk of coronary heart disease events. Statins reduce progression of CIMT and coronary heart disease risk in proportion to the reduction in ...
Baldassarre, Damiano   +22 more
core   +1 more source

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