Analysis of α-lipoprotein cholesterol in 50 μl of plasma
A micromethod for quantitation of α-lipoprotein cholesterol was devised for gas–liquid chromatography to minimize plasma sample size and facilitate lipid studies using capillary blood from children or small animals. α-Lipoprotein cholesterol was measured
R.F. Lutmer +7 more
doaj +1 more source
Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries. [PDF]
Lipoprotein(a), Lp(a), is a modified low-density lipoprotein particle that contains apolipoprotein(a), encoded by LPA, and is a highly heritable, causal risk factor for cardiovascular diseases that varies in concentrations across ancestries. Here, we use
Alver, Maris +38 more
core +1 more source
Sir, Malle and Sattler's excellent review links lipids with the release of serotonin from platelets.' It is therefore, of interest that correlations between serum cholesterol and intraplatelet/plasma serotonin concentrations have been reported.'-* Moreover, reducing serum cholesterol and low density lipoprotein (LDL) concentrations normalised ...
A F Wider +3 more
openaire +3 more sources
Phosphatidylinositol promotes cholesterol transport in vivo
To examine the role that lipoprotein charge plays in cholesterol metabolism in vivo, we characterized the effects of an intravenous injection of 40 μmol of an uncharged phospholipid (phosphatidylcholine, PC) or an anionic phospholipid ...
Christopher J. Stamler +5 more
doaj +1 more source
Soluble levels of receptor for advanced glycation endproducts and dysfunctional high-density lipoprotein in persons infected with human immunodeficiency virus: ACTG NWCS332. [PDF]
The role of high-density lipoprotein (HDL) function and advanced glycation end products (AGEs) in HIV-related atherosclerotic cardiovascular disease (CVD) is unclear.
Aberg, Judith A +5 more
core +1 more source
Replacement of dietary saturated fatty acids by trans fatty acids lowers serum HDL cholesterol and impairs endothelial function in healthy men and women [PDF]
We tested whether trans fatty acids and saturated fatty acids had different effects on flow-mediated vasodilation (FMD), a risk marker of coronary heart disease (CHD). Consumption of trans fatty acids is related to increased risk of CHD, probably through
Bots, M.L., Katan, M.B., Roos, N.M., de
core +2 more sources
Evolving lipoprotein risk factors: lipoprotein(a) and oxidized low-density lipoprotein [PDF]
Abstract Cardiovascular disease is the leading cause of morbidity and mortality in Westernized populations. Evolving lipoprotein risk factors include LDL oxidation and lipoprotein(a) [lp(a)]. Several lines of evidence support a role for oxidatively modified LDL in atherogenesis and its in vivo existence.
openaire +3 more sources
Human plasma cholesteryl ester transfer protein (CETP) is a 476-residue hydrophobic glycoprotein that catalyzes the heterotransfer of cholesteryl esters and triacylglycerols among lipoproteins: Mutations in the CETP gene have been identified, mostly in ...
Evelyn M. Teh +3 more
doaj +1 more source
Lipid Metabolism and Comparative Genomics [PDF]
Unilever asked the Study Group to focus on two problems. The first concerned dysregulated lipid metabolism which is a feature of many diseases including metabolic syndrome, obesity and coronary heart disease.
Jones, Janette +5 more
core
The secondary structure of apolipoprotein A-I on 9.6-nm reconstituted high-density lipoprotein determined by EPR spectroscopy. [PDF]
Apolipoprotein A-I (ApoA-I) is the major protein component of high-density lipoprotein (HDL), and is critical for maintenance of cholesterol homeostasis.
Borja, Mark S +5 more
core +1 more source

