Results 61 to 70 of about 999,472 (383)

The 1(st) and the 2(nd) Italian Consensus Conferences on low-density lipoprotein-apheresis. A practical synopsis and update [PDF]

, 2016
The clinical indications and guidelines for low-density lipoprotein (LDL)-apheresis set by the 1(st) Italian Consensus Conference held in Ostuni in 1990 and completed in 1992, but never published, are reported schematically.
Stefanutti, Claudia
core   +1 more source

Characterization of two new point mutations in the low density lipoprotein receptor genes of an English patient with homozygous familial hypercholesterolemia.

Journal of Lipid Research, 1992
Two new point mutations have been detected in the low density lipoprotein (LDL) receptor gene of a patient with a clinical diagnosis of homozygous familial hypercholesterolemia (FH).
JC Webb, XM Sun, DD Patel, SN McCarthy, BL Knight, AK Soutar   +5 more
doaj  

Bifurcation analysis of a free boundary model of plaque formation associated with the cholesterol ratio [PDF]

arXiv, 2020
The low-density lipoprotein (LDL)/high-density lipoprotein (HDL)-cholesterol ratio has been shown a high correlation with the cardiovascular risk assessment. Is it possible to quantify the correlation mathematically? In this paper, we develop a bifurcation analysis for a mathematical model of the plaque formation with a free boundary in the early stage
arxiv  

Lipoprotein(a) concentration and the risk of coronary heart disease, stroke, and nonvascular mortality.

Journal of the American Medical Association (JAMA), 2009
CONTEXT Circulating concentration of lipoprotein(a) (Lp[a]), a large glycoprotein attached to a low-density lipoprotein-like particle, may be associated with risk of coronary heart disease (CHD) and stroke. OBJECTIVE To assess the relationship of Lp(a)
S. Erqou, S. Kaptoge, P. Perry, E. di Angelantonio, A. Thompson, I. White, S. Marcovina, R. Collins, S. Thompson, J. Danesh   +9 more
semanticscholar   +1 more source

ADAPT NXT: Fixed Cycles or Every‐Other‐Week IV Efgartigimod in Generalized Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This phase 3b, open‐label, randomized ADAPT NXT study investigated the efficacy, safety, and tolerability of efgartigimod administered in either a fixed cycles dosing regimen (3 cycles of 4 once‐weekly infusions, with 4 weeks between cycles) or a cycle followed by every‐other‐week (Q2W) dosing.
Ali A. Habib, Kristl G. Claeys, Vera Bril, Yessar Hussain, Kelly Gwathmey, Gregory Sahagian, Elena Cortés‐Vicente, Edward Brauer, Deborah Gelinas, Anne Sumbul, Rosa H. Jimenez, Daniela Hristova, Delphine Masschaele, Renato Mantegazza, Andreas Meisel, Shahram Attarian, On behalf of the ADAPT NXT Study Group   +16 more
wiley   +1 more source

Apolipoprotein M [PDF]

, 2004
Apolipoprotein M (apoM) is a 26-kDa protein that is mainly associated with high-density lipoprotein (HDL) in human plasma, with a small proportion present in triglyceride-rich lipoproteins (TGRLP) and low-density lipoproteins (LDL).
Luo, Guanghua, Nilsson-Ehle, Peter, Xu, Ning, Zhang, Xiaoying   +3 more
core   +3 more sources

Behavior of human apolipoprotein A-I: phospholipid and apoHDL:phospholipid complexes in vitro and after injection into rabbits

Journal of Lipid Research, 1988
Apolipoprotein A-I was purified from human high density lipoprotein and complexed with polyunsaturated phosphatidylcholine (PC) in deoxycholate (Lipostabil); the bile salt was removed subsequently by dialysis.
J Koizumi, M Kano, K Okabayashi, A Jadhav, G R Thompson   +4 more
doaj  

Apolipoprotein Mimetic Peptides: Potential New Therapies for Cardiovascular Diseases

Cells, 2021
Since the seminal breakthrough of treating diabetic patients with insulin in the 1920s, there has been great interest in developing other proteins and their peptide mimetics as therapies for a wide variety of other medical disorders. Currently, there are
Anna Wolska, Mart Reimund, Denis O. Sviridov, Marcelo J. Amar, Alan T. Remaley   +4 more
doaj   +1 more source

Oxysterols in Vascular Cells and Role in Atherosclerosis [PDF]

Implication of Oxysterols and Phytosterols in Aging and Human Diseases, 1440, Springer International Publishing, pp.213-229, 2024, Advances in Experimental Medicine and Biology
Atherosclerosis is a major cardiovascular complication of diseases associated with elevated oxidative stress such as type 2 diabetes and metabolic syndrome. In these situations, low density lipoproteins (LDL) undergo oxidation. Oxidized LDL display proatherogenic activities through multiple and complex mechanisms which lead to dysfunctions of vascular ...
arxiv   +1 more source

Mechanism of action of fibrates on lipid and lipoprotein metabolism.

Circulation, 1998
Treatment with fibrates, a widely used class of lipid-modifying agents, results in a substantial decrease in plasma triglycerides and is usually associated with a moderate decrease in LDL cholesterol and an increase in HDL cholesterol concentrations ...
B. Staels, J. Dallongeville, J. Auwerx, K. Schoonjans, E. Leitersdorf, J. Fruchart   +5 more
semanticscholar   +1 more source