Results 1 to 10 of about 20,820 (98)
Indian Heart JLp(a) is a genetically determined, heritable, independent and causal risk factor for ASCVD. About 1 in 5 people worldwide have elevated Lp(a) (>50 mg/dL or >125 nmol/L) whereas in Indians it is 25 %. Epidemiological, genome-wide association and mendelian randomization studies have demonstrated an association between elevated Lp(a) levels and increased ...
Ghose T.
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Studies on the heterogeneity of human serum Lp lipoproteins and on the occurrence of double Lp lipoprotein variants [PDF]
Biochemical Genetics, 1973 Lp lipoproteins have been prepared by a mild method from the serum of a large number of individuals. Approximately 25% of the individuals tested showed the presence of a double Lp peak in analytical ultracentrifuge diagrams. These double peaks were designated Lp(a)-1 and Lp(a)-2 to distinguish them from the single Lp(a) peak.
Harvie, Nancy Reid, Schultz, Jane S.
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Hepatic uptake and deacylation of the LPS in bloodborne LPS-lipoprotein complexes [PDF]
Innate Immunity, 2012 Much evidence indicates that bacterial LPS (endotoxin) is removed from the bloodstream mainly by the liver, yet the hepatic uptake mechanisms remain uncertain and controversial. In plasma, LPS can be either ‘free’ (as aggregates, bacterial membrane fragments or loosely bound to albumin, CD14, or other proteins) or ‘bound’ (complexed with lipoproteins).
Baomei, Shao +3 more
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Lipoprotein composition and serum Lp(a) lipoprotein in hypobetalipoproteinaemia. [PDF]
Journal of Clinical Pathology, 1995 A family with hypobetalipoproteinaemia was studied to examine the Lp(a) lipoprotein, lipoprotein cholesterol, and triglyceride composition of the serum lipids. Lp(a) lipoprotein was measured by immunoassay. Serum lipoproteins were separated by ultracentrifugation. Cholesterol and triglycerides were measured using standard enzymatic assays.
M, Crook, R, Swaminathan
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Lp(a) Lipoprotein, Vascular Disease, and Mortality in the Elderly [PDF]
New England Journal of Medicine, 2003 As compared with what is known about predictors of vascular events in middle-aged persons, less is known about these events in the elderly. Lp(a) lipoprotein, which plays an important part in atherothrombogenesis, has been associated with an increased risk of vascular disease. We investigated this relation among older U.S. adults.In a prospective study
Raiyo, A.A., Thach, C., Tracy, R.
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Radioimmunoassay of human plasma Lp(a) lipoprotein
Journal of Lipid Research, 1977 A quantitative immunodiffusion assay demonstrated Lp(a) lipoprotein in 91% (911 of 1000) of subjects. In order to quantitate Lp(a) in all plasma, a sensitive and specific double antibody radioimmunoassay was developed. The between-assay coefficient of variation was 8%.
J J Albers, J L Adolphson, W R Hazzard
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Focus on Lipoprotein(a) – Lp(a)
European Heart Journal SupplementsAbstract Lipoprotein(a) [Lp(a)] is a causal and independent cardiovascular risk factor for atherosclerotic cardiovascular disease and calcific aortic valve stenosis, with elevated levels observed in approximately 20% of the general population.
Marta Biolo +8 more
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Molecular parameters of Lp(a)‐lipoprotein by light scattering
FEBS Letters, 1979 Lp(a) lipoprotein is thought to be an addi- tional risk factor for coronary heart disease [l-3]. Papers published up to now have been concerned with its electrophoretical mobility [4,5], its chemical com- position [6,7] and its physiological role [l-3]. Con- cerning the size of the particle, only disagreeing information has been reported [8].
Eigner, Dieter +3 more
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[Lp(a) and its role in cardiovascular diseases]. [PDF]
Dtsch Med Wochenschr, 2022 Reuser A, Koenig W, Laufs U.
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