Results 11 to 20 of about 24,826 (263)

New insights into the role of lipoprotein(a)-associated lipoprotein-associated phospholipase A(2) in atherosclerosis and cardiovascular disease

Arteriosclerosis, Thrombosis, and Vascular Biology, 2007
Lipoprotein(a) [Lp( a)] plays an important role in atherosclerosis. The biological effects of Lp( a) have been attributed either to apolipoprotein(a) or to its low-density lipoprotein-like particle.
Tselepis, A. D., Tsimikas, S., Tsironis, L. D.   +2 more
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Lipoprotein(a): Just an Innocent Bystander in Arterial Hypertension? [PDF]

, 2023
Elevated plasma lipoprotein(a) [Lp(a)] is a relatively common and highly heritable trait conferring individuals time-dependent risk of developing atherosclerotic cardiovascular disease (CVD).
Picci A., Sechi L. A., Vacca A., Catena C., Brosolo G., Capilupi F., Da Porto A., Marcante S., Capilupi P., Bertin N., Vivarelli C., Comand J., Bulfone L.   +12 more
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Genome-wide association study of genetic determinants of LDL-c response to atorvastatin therapy: importnace of Lp(a) [PDF]

, 2012
We carried out a genome-wide association study (GWAS) of LDL-c response to statin using data from participants in the Collaborative Atorvastatin Diabetes Study (CARDS; n = 1,156), the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT; n = 895), and the ...
Postmus, Iris, Colhoun, H.M., McKeigue, Paul M, Stanton, A.V., Trompet, S., Hyde, Craig, Colhoun, Helen M, Caulfield, M., Shields, Denis C., Hitman, Graham A, CARDS, Poulter, Neil, Shields, D.C., Sever, P., Chatterjee, Aurobindo, Trompet, Stella, Durrington, Paul N, Deshmukh, H.A., DeMicco, D.A., Calle, Roberto A., Hitman, Graham A., Neil, A., McKeigue, Paul M., Fuller, John H., Postmus, I., Hitman, G.A., DeMicco, David A., Johnson, T., ?, ?, Calle, Roberto A, Betteridge, D.J., Livingstone, Shona, Ford, Ian, McKeigue, P.M., Stanton, Alice V., Jukema, J.W., Johnson, Toby, Durrington, Paul N., Neil, Andrew, PROSPER Investigators, Livingstone, S., Jukema, J. Wouter, ASCOT, Colhoun, Helen, Ford, I., Sever, Peter, Fuller, J.H., Jukema, J Wouter, Caulfield, Mark, Fuller, John H, Chatterjee, A., Deshmukh, Harshal A, Calle, R.A., Hyde, C., Charlton-Menys, V., Poulter, N., Charlton-Menys, Valentine, DeMicco, David A, Betteridge, D John, McKeigue, Paul M.; id_orcid, Betteridge, D. John, Durrington, P.N., Colhoun, Helen M., Shields, Denis C, Deshmukh, Harshal A., Stanton, Alice V   +65 more
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Isolation and partial characterization of lipoprotein A-II (LP-A-II) particles of human plasma [PDF]

, 1992
High density lipoproteins (HDL) consist of a mixture of chemically and functionally distinct families of particles defined by their characteristic apolipoprotein (Apo) composition.
Bekaert, Etienne D., Knight-Gibson, Carolyn, Alaupovic, Petar, Laux, Matthew J., Norum, Robert A., Ayrault-Jarrier, M.   +5 more
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Acute lower limb ischemia due to thrombo-embolic arterial occlusions in two previously healthy men with markedly elevated Lp(a) [PDF]

, 2006
Lipoprotein (a) (Lp(a)) is a well-documented risk factor for atherosclerotic cardiovascular disease. Its role in acute thrombo-embolic occlusions of peripheral arteries is not known.
Bedarida, Gabriella V., Tatò, Federico, Bedarida, Gabriella V, Hoffmann, Ulrich   +3 more
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Sequencing of Lp-PLA2-encoding PLA2G7 gene in 2000 Europeans reveals several rare loss-of-function mutations. [PDF]

, 2011
Elevated plasma levels of lipoprotein-associated phospholipase A(2) (Lp-PLA2) activity have been shown to be associated with increased risk of coronary heart disease and an inhibitor of this enzyme is under development for the treatment of that condition.
Bacanu, S.A., E S Manas, Kong, X., Aponte, J., Manas, ES, S-A Bacanu, Cardon, L., Song, K, Nelson, MR, K Song, J Aponte, X Kong, Whittaker, JC, M R Nelson, Manas, E.S., Yuan, X., D M Waterworth, Whittaker, J.C., Kong, X, Cardon, L, Waterworth, DM, Yuan, X, L Cardon, Mooser, V.E., X Yuan, Song, K., Aponte, J, Bacanu, S-A, Nelson, M.R., Mooser, VE, J C Whittaker, Waterworth, D.M., V E Mooser   +32 more
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Lipoprotein (a): a genetic marker for cardiovascular disease and target for emerging therapies

, 2021
Lipoprotein(a) [Lp(a)] is an established cardiovascular risk factor, and growing evidence indicates its causal association with atherosclerotic disease because of the proatherogenic low-density lipoprotein (LDL)-like properties and the prothrombotic ...
Gragnano F, Riccio C, Cesaro A, Arca M, D'Erasmo L, Calabrò P, Moscarella E, Caiazza M, Monda E, Schiavo A, Conte M, Coletta S, Fimiani F, Limongelli G   +13 more
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Genetic Variants Associated with Lp(a) Lipoprotein Level and Coronary Disease

, 2017
BACKGROUND: An increased level of Lp(a) lipoprotein has been identified as a risk factor for coronary artery disease that is highly heritable. The genetic determinants of the Lp(a) lipoprotein level and their relevance for the risk of coronary disease ...
Gigante, B, Hopewell, JC, Bennett, D, PROCARDIS Consortium, , Heath, SC, Collins, R, Farrall, M, Lathrop, M, Peden, JF, Parish, S, de Faire, U, Watkins, H, Barlera, S, Rust, S, Clarke, R, Franzosi, MG, Green, FR, Malarstig, A, Leander, K, Hamsten, A, Kyriakou, T, Goel, A, Seedorf, U, Silveira, A   +23 more
core   +2 more sources

Rheumatoid Arthritis and Coronary Artery Calcium Progression: A Case Cohort Analysis From ELSA‐Brasil

Arthritis Care &Research, EarlyView.
Objective To investigate the association between rheumatoid arthritis (RA) and coronary artery calcium (CAC) prevalence, incidence, and progression over four years in adults without prior cardiovascular disease. Methods A case‐cohort study within the Brazilian Longitudinal Study of Adult Health (ELSA‐Brasil) included 585 participants (86 patients with ...
Patrícia Fonseca Estrada, Marcos Rafael N. Cavalcante, Itamar de Souza Santos, Márcio S. Bittencourt, Vandrize Meneghini, Paulo A. Lotufo, Alessandra C. Goulart, Isabela M. Bensenor   +7 more
wiley   +1 more source

Epidemiological Study of Lipoprotein (a) in Okinawa [PDF]

, 1995
A study of serum levels of lipoprotein (a) (Lp (a)) was performed among 217 normal adults including 135 men and 82 women in the northern part of Okinawa. Ages of the subjects ranged from 24 to 76 with an average of 49 years.
Tamamoto, Tohru, Sakugawa, Hiroshi, Toda, Takayoshi, Yamasiro, Tetsu, Nagata, Junichi, Yamashiro, Akihiro   +5 more
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