Results 91 to 100 of about 91,018 (321)

Familial chylomicronemia due to a circulating inhibitor of lipoprotein lipase activity

open access: yesJournal of Lipid Research, 1983
A mother and her son who have lipoprotein phenotype I are described. They differed from subjects with lipoprotein lipase deficiency in that lipoprotein lipase was present in adipose tissue respectively at 30- and 2-fold the levels seen in normal subjects,
J D Brunzell   +7 more
doaj  

IDOL regulates systemic energy balance through control of neuronal VLDLR expression. [PDF]

open access: yes, 2019
Liver X receptors limit cellular lipid uptake by stimulating the transcription of Inducible Degrader of the LDL Receptor (IDOL), an E3 ubiquitin ligase that targets lipoprotein receptors for degradation.
Ahn, In Sook   +29 more
core  

Milk Lipoprotein Lipases: A Review

open access: yesJournal of Dairy Science, 1976
Lipoprotein lipase activity has been found in the milks from severals species where it is assumed to result from leakage from the mammary gland into milk. The function of the enzyme in the gland is apparently to assist in the transfer of blood lipoprotein triacylglycerol fatty acids into milk triacylglycerols.
Robert G. Jensen, R.E. Pitas
openaire   +3 more sources

Autoimmunity in MASLD: Focus on autoantibodies, anti‐apolipoprotein A1 IgG and G protein‐coupled receptors

open access: yesEuropean Journal of Clinical Investigation, EarlyView.
This review outlines the potential role of anti‐GPCR autoantibodies in MASLD/MASH, given their involvement in a wide range of diseases and their possible contribution to MASLD/MASH pathophysiology. We also focused on anti‐ApoA1 autoantibodies, sharing functional features with anti‐GPCR autoantibodies and have been shown to promote liver steatosis in ...
Sabrina Pagano   +3 more
wiley   +1 more source

Identification of the epitope of a monoclonal antibody that inhibits heparin binding of lipoprotein lipase: new evidence for a carboxyl-terminal heparin-binding domain

open access: yesJournal of Lipid Research, 1998
A panel of 13 monoclonal antibodies to avian lipoprotein lipase (LPL) was screened for inhibition of LPL binding to primary avian adipocytes. One monoclonal antibody, designated xCAL (monoclonal antibody to chicken adipose lipoprotein lipase) 3-6a, was ...
Rebecca A. Sendak   +3 more
doaj  

STIM2β is a Ca2+ signaling modulator for the regulation of mitotic clonal expansion and PPARG2 transcription in adipogenesis

open access: yesThe FEBS Journal, EarlyView.
STIM2β acts as the intracellular Ca2+ regulator during adipogenesis. By inhibiting intracellular Ca2+ levels and SOCE, STIM2β promotes mitotic clonal expansion in the early stage of adipogenesis. In the terminal differentiation stage, increased SOCE activity enhances PPARG2 gene transcription.
Su Ji Jeong   +3 more
wiley   +1 more source

A compound heterozygote for lipoprotein lipase deficiency, Val69–>Leu and Gly188–>Glu: correlation between in vitro LPL activity and clinical expression.

open access: yesJournal of Lipid Research, 1994
We analyzed the molecular defects in the lipoprotein lipase gene of a patient with type I hyperlipidemia suffering from recurrent pancreatitis, indicative for lipoprotein lipase deficiency.
T. Bruin   +6 more
doaj  

Emerging roles for integrated stress response signaling in homeostasis

open access: yesThe FEBS Journal, EarlyView.
Integrated stress response (ISR), an evolutionarily conserved eukaryotic stress‐adaptive program in eukaryotes, has also been implicated in homeostatic functions. This review covers a broad body of literature and presents several homeostatic functions of ISR in the absence of stress: (a) developmental processes (morphogenesis, differentiation, aging), (
Shyama Nandakumar   +2 more
wiley   +1 more source

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