Results 91 to 100 of about 45,979 (322)

Familial chylomicronemia due to a circulating inhibitor of lipoprotein lipase activity

open access: yesJournal of Lipid Research, 1983
A mother and her son who have lipoprotein phenotype I are described. They differed from subjects with lipoprotein lipase deficiency in that lipoprotein lipase was present in adipose tissue respectively at 30- and 2-fold the levels seen in normal subjects,
J D Brunzell   +7 more
doaj  

Pathways-driven Sparse Regression Identifies Pathways and Genes Associated with High-density Lipoprotein Cholesterol in Two Asian Cohorts [PDF]

open access: yesarXiv, 2013
Standard approaches to analysing data in genome-wide association studies (GWAS) ignore any potential functional relationships between genetic markers. In contrast gene pathways analysis uses prior information on functional structure within the genome to identify pathways associated with a trait of interest. In a second step, important single nucleotide
arxiv  

Identification of the epitope of a monoclonal antibody that inhibits heparin binding of lipoprotein lipase: new evidence for a carboxyl-terminal heparin-binding domain

open access: yesJournal of Lipid Research, 1998
A panel of 13 monoclonal antibodies to avian lipoprotein lipase (LPL) was screened for inhibition of LPL binding to primary avian adipocytes. One monoclonal antibody, designated xCAL (monoclonal antibody to chicken adipose lipoprotein lipase) 3-6a, was ...
Rebecca A. Sendak   +3 more
doaj  

A compound heterozygote for lipoprotein lipase deficiency, Val69–>Leu and Gly188–>Glu: correlation between in vitro LPL activity and clinical expression.

open access: yesJournal of Lipid Research, 1994
We analyzed the molecular defects in the lipoprotein lipase gene of a patient with type I hyperlipidemia suffering from recurrent pancreatitis, indicative for lipoprotein lipase deficiency.
T. Bruin   +6 more
doaj  

Chromosome‐level genome assembly and population genomic analysis provide insights into the genetic diversity and adaption of Schizopygopsis younghusbandi on the Tibetan Plateau

open access: yesIntegrative Zoology, EarlyView.
We have constructed the chromosome‐scale genome and investigated the evolutionary genomics of Schizopygopsis younghusbandi, a fish species native to the Yarlung Tsangpo River on the Tibetan Plateau. Our study indicated that this species diverged from other Schizothoracine fish approximately 4.2 million years ago, during the Neogene Tibetan uplift ...
Chaowei ZHOU   +15 more
wiley   +1 more source

Sib-pair linkage analysis of longitudinal changes in lipoprotein risk factors and lipase genes in women twins

open access: yesJournal of Lipid Research, 2000
Based on longitudinal twin data in women, we have previously demonstrated a genetic influence on changes in lipoprotein risk factors, blood pressure measurements, and body mass index over a decade.
Yechiel Friedlander   +4 more
doaj  

Drug‐Based Lifespan Extension in Mice Strongly Affects Lipids Across Six Organs

open access: yesAging Cell, EarlyView.
Using six interventions that have previously shown to differentially increase lifespan in male and female mice, we here show significant metabolic changes across organs, sex and metabolic pathways. Specifically, lipid responses were prominent across organs, but also in a sexually dimorphic manner.
Sara Greenfield   +7 more
wiley   +1 more source

The Effect of Melinjo Peel Extract in Activity of Lipoprotein Lipase Enzym of The Rats Fed a Hypercholesterolemia Diet

open access: yesJurnal Ilmiah Kedokteran Wijaya Kusuma, 2018
The intake of saturated fat and cholesterol that comes from food digested in the intestine resulting in free fatty acids, triglycerides, phospholipids, and cholesterol.
Athira Demitri
doaj  

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