Results 11 to 20 of about 387,913 (205)
High-Density Lipoprotein (HDL) Triglyceride and Oxidized HDL: New Lipid Biomarkers of Lipoprotein-Related Atherosclerotic Cardiovascular Disease [PDF]
Lipid markers are well-established predictors of vascular disease. The most frequently measured lipid markers are total cholesterol, high-density lipoprotein (HDL)-cholesterol (HDL-C), LDL cholesterol (LDL-C), and triglyceride. HDL reduces atherosclerosis by multiple mechanisms, leading to a reduced risk of cardiovascular disease, and HDL-C, as a ...
Tomoyuki Ito, Tomoyuki Ito, Fumiaki Ito
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High-density lipoproteins may play a crucial role in COVID-19
Background Lipids play a central role in the virus life cycle and are a crucial target to develop antiviral therapeutics. Importantly, among the other lipoproteins, the ‘good cholesterol’ high-density lipoprotein (HDL) has been widely studied for its ...
Minu Nain+3 more
doaj +1 more source
HDL and plaque regression in a multiphase model of early atherosclerosis [PDF]
Atherosclerotic plaques are accumulations of cholesterol-engorged macrophages in the artery wall. Plaque growth is initiated and sustained by the deposition of low density lipoproteins (LDL) in the artery wall. High density lipoproteins (HDL) counterbalance the effects of LDL by accepting cholesterol from macrophages and removing it from the plaque. In
arxiv +1 more source
Paraoxonase 1 as an important antiatherogenic agent
The inverse relationship between High Density Lipoproteins (HDL) level and risk of ischaemic heart disease was proved by many epidemiological studies. Although the main mechanism of antiatherogenic activity of HDL is a reverse transport of cholesterol ...
Ewa Lidia Krzewicka-Romaniuk+3 more
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The strong inverse relationship between HDL level and risk for coronary artery disease has been attributed to different mechanisms. More than 30 years ago, Glomset1 proposed that HDL mediates the transfer of cholesterol from peripheral tissues to the liver, where the sterol and its oxygenated products are excreted into the bile.
Jay W. Heinecke+2 more
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Individuals with familial hypercholesterolemia (FH) have an increased risk of cardiovascular disease. Treatment is mainly low-density lipoprotein cholesterol (LDL-C) reduction.
Liv Nesse Hande+8 more
doaj +1 more source
Plasma lipoproteins play critical roles in energy metabolism and inflammation. Concentrations of high-density lipoproteins (HDL) are linked to reproductive outcomes and milk yields in dairy cattle.
Marcos Jofree Duran+3 more
doaj +1 more source
HDL is the major lipoprotein carrier of plasma F2-isoprostanes [PDF]
Enhanced oxidative stress is implicated in the development of atherosclerosis in humans and animal models. F(2)-isoprostanes are formed in vivo via free radical peroxidation of arachidonic acid, and their quantification has allowed assessment of oxidative stress in vivo.
Julie M. Proudfoot+5 more
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Subfractions of high-density lipoprotein (HDL) and dysfunctional HDL in chronic kidney disease patients [PDF]
A number of studies have shown that chronic kidney disease (CKD) is associated with increased risk for cardiovascular disease (CVD). Chronic kidney disease is characterized by significant disturbances in lipoprotein metabolism, including differences in quantitative and qualitative content of high-density lipoprotein (HDL) particles. Recent studies have
Maciej Banach+1 more
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Promotion of Lymphocyte Growth by High Density Lipoproteins (HDL) [PDF]
The characteristics and physiological relevance of the high density lipoprotein (HDL) binding site on unstimulated and mitogen activated human peripheral blood lymphocytes have been investigated. At 37 degrees C, specific binding/uptake of fluorescent (dioctadecylin-docarbocyanine, DiI) HDL was observed by cells from healthy donors as well as by those ...
K. N. Traill+6 more
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