The Current Status of Research on High-Density Lipoproteins (HDL): A Paradigm Shift from HDL Quantity to HDL Quality and HDL Functionality. [PDF]
The quantity of high-density lipoproteins (HDL) is represented as the serum HDL-C concentration (mg/dL), while the HDL quality manifests as the diverse features of protein and lipid content, extent of oxidation, and extent of glycation. The HDL functionality represents several performance metrics of HDL, such as antioxidant, anti-inflammatory, and ...
Cho KH.
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The pleiotropic vasoprotective functions of high density lipoproteins (HDL). [PDF]
The pleiotropic functions of circulating high density lipoprotein (HDL) on peripheral vascular health are well established. HDL plays a pivotal role in reverse cholesterol transport and is also known to suppress inflammation, endothelial activation and apoptosis in peripheral vessels.
Boyce G, Button E, Soo S, Wellington C.
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Relationship of the low-density lipoprotein (LDL)/high-density lipoprotein (HDL) index with antioxidant enzymes and with the oxLDL/HDL index [PDF]
The low-density lipoprotein (LDL)/high-density lipoprotein (HDL) index is a predictive factor for atherosclerosis, which is associated with oxidative modifications.To assess the association of the index with oxidative stress markers.444 subjects were included and were clinically, anthropometrically and biochemically characterized; superoxide dismutase,
Eduardo Monjaraz-Guzmán+8 more
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Effects of superoxide anion attack on the lipoprotein HDL
AbstractHigh-density lipoprotein (HDL) is an anti-atherosclerotic lipoprotein. Thanks to the activity of apolipoprotein ApoA1, the principal protein component of HDL, this last is responsible for converting cholesterol into ester form and transporting excessive cholesterol to the liver (“reverse cholesterol transport” RCT). When HDL undergoes oxidation,
Napolitano G.+5 more
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High-Density Lipoprotein (HDL) Triglyceride and Oxidized HDL: New Lipid Biomarkers of Lipoprotein-Related Atherosclerotic Cardiovascular Disease [PDF]
Lipid markers are well-established predictors of vascular disease. The most frequently measured lipid markers are total cholesterol, high-density lipoprotein (HDL)-cholesterol (HDL-C), LDL cholesterol (LDL-C), and triglyceride. HDL reduces atherosclerosis by multiple mechanisms, leading to a reduced risk of cardiovascular disease, and HDL-C, as a ...
Tomoyuki Ito, Tomoyuki Ito, Fumiaki Ito
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The strong inverse relationship between HDL level and risk for coronary artery disease has been attributed to different mechanisms. More than 30 years ago, Glomset1 proposed that HDL mediates the transfer of cholesterol from peripheral tissues to the liver, where the sterol and its oxygenated products are excreted into the bile.
Jay W. Heinecke+2 more
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HDL is the major lipoprotein carrier of plasma F2-isoprostanes [PDF]
Enhanced oxidative stress is implicated in the development of atherosclerosis in humans and animal models. F(2)-isoprostanes are formed in vivo via free radical peroxidation of arachidonic acid, and their quantification has allowed assessment of oxidative stress in vivo.
Julie M. Proudfoot+5 more
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hdl a molecular view of the classic antiatherogenic lipoprotein [PDF]
L'estudi del metabolisme de les HDL (lipoproteïnes de densitat alta) i la seva relació amb l'arteriosclerosi és un tema complex, en el qual, recentment, s'han fet avenços importants. Primer, s'ha demostrat que les HDL tenen una acció antiaterogènica. Segon, s'ha establert que aquesta acció és deguda a fraccions que tenen apoA-I però no apoA-II. Tercer,
Ribas, Vicent+2 more
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Oxidized low-density lipoprotein inhibits hepatitis C virus cell entry in human hepatoma cells. [PDF]
Cell entry of hepatitis C virus, pseudoparticles (HCVpp) and cell culture grown virus (HCVcc), requires the interaction of viral glycoproteins with CD81 and other as yet unknown cellular factors.
Boullier, Agnès+6 more
core +1 more source
Subfractions of high-density lipoprotein (HDL) and dysfunctional HDL in chronic kidney disease patients [PDF]
A number of studies have shown that chronic kidney disease (CKD) is associated with increased risk for cardiovascular disease (CVD). Chronic kidney disease is characterized by significant disturbances in lipoprotein metabolism, including differences in quantitative and qualitative content of high-density lipoprotein (HDL) particles. Recent studies have
Maciej Banach+1 more
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