Results 231 to 240 of about 88,978 (314)

Sex‐specific associations of Roseburia with uric acid metabolism and hyperuricemia risk in females

iMetaOmics, EarlyView.
Researchers recruited 623 participants, including 270 females, and used 16S rDNA sequencing to investigate gender differences in hyperuricemia. In healthy females, Roseburia was enriched, positively correlating with estrogen and negatively with uric acid, suggesting it is a potential biomarker affecting uric acid levels in females.
Zhihan Yang, Zeng Zhang, Mohan Chen, Jin Hu, Yingqi Qiu, Shijia Lin, Xiaolu Zhou, Jiachao Zhang, Shuaiming Jiang   +8 more
wiley   +1 more source

Characterization of pig skeletal muscle transcriptomes in response to low temperature

Veterinary Medicine and Science, Volume 9, Issue 1, Page 181-190, January 2023., 2023
Low temperature changes the gene expression pattern and biological pathway in pig skeletal muscle. Under low temperature, biological pathways of lipid, amino acid, and carbohydrate metabolism; signal transduction; endocrine, immune, and nervous system; cardiovascular disease; infectious diseases caused by bacteria or viruses; and neurodegenerative ...
DongJie Zhang, Liang Wang, ShouZheng Ma, Hong Ma, Di Liu   +4 more
wiley   +1 more source

Transfer learning identifies bacterial signatures for cross‐regional diagnosis of type 2 diabetes and enable stage‐sensitive dietary fiber intervention

iMetaOmics, EarlyView.
DeepMicroFinder is a deep learning framework designed to update the existing disease diagnosis model to generate a transfer model by leveraging region‐specific microbiome datasets and transfer learning approach. This framework effectively overcomes the limitation of regional effects in the gut microbiome, enabling accurate cross‐regional disease ...
Qunye Zhang, Nan Wang, Fanghua Zhang, Bin Chen, Yihui Wang, Zhongchao Wang, Changying Zhao, Chuandi Jin, Dashuang Sheng, Kaile Yue, Daifeng Jiang, Liaomei Gao, Haohong Zhang, Zixin Kang, Mingyue Cheng, Xiaoli Ma, Haiyan Wang, Dongming Hu, Jun Wang, Yuantao Liu, Chenhong Zhou, Minxiu Yao, Guoping Zhao, Yangang Wang, Zhe Wang, Kang Ning, Lei Zhang   +26 more
wiley   +1 more source

Veterinary nanomedicine: Pros and cons

Veterinary Medicine and Science, Volume 9, Issue 1, Page 494-506, January 2023., 2023
Abstract In recent years, nanotechnology has improved life with continuous growth in different fields. Nanoparticles can be employed in industry, imaging, engineering, and various biomedical filed because of their special physicochemical properties like rapid, effective, highly specific solutions, higher stability, biodegradability, biocompatibility ...
Fariba Jafary, Shima Motamedi, Isaac Karimi   +2 more
wiley   +1 more source

Safety Evaluation of Serendipity Berry Sweet Protein From Komagataella phaffii

Journal of Applied Toxicology, EarlyView.
ABSTRACT Serendipity Berry Sweet Protein (sweelin) is a novel hyper‐sweet thermophilic protein designed using Artificial Intelligence Computational Protein Design (AI‐CPD) to improve the stability and sensory profile of the protein found in serendipity berry (Dioscoreophyllum cumminsii).
Yael Lifshitz, Shira Paz, Rotem Saban, Inbar Zuker, Hagay Shmuely, Katy Gorshkov, Jwar Meetro, Shahrzad Tafazoli, Trung Vo, Gabriela Amiram, Carmit Shani Levi, Uri Lesmes, Ilan Samish   +12 more
wiley   +1 more source

HDL-Cholesterol and Triglycerides Dynamics: Essential Players in Metabolic Syndrome. [PDF]

Antioxidants (Basel)
Alcover S, Ramos-Regalado L, Girón G, Muñoz-García N, Vilahur G.   +4 more
europepmc   +1 more source

Allergenicity, Genotoxicity and Subchronic Toxicity Assessment of IgG Binding Protein LT Produced From Aspergillus oryzae

Journal of Applied Toxicology, EarlyView.
ABSTRACT Gastrointestinal health is one of the fastest growing areas in the food and beverage industry, as its importance to overall health and well‐being is becoming increasingly recognized. Immunoglobulins play a key role in protecting the gastrointestinal tract, and nonbovine sources of immunoglobulins (including camel milk, which has a long history
Kirt R. Phipps, Sachin Patel, Kevin Scaife, Toby Holmes, Alica Šoltésová, Sandra Wingaard Thrane, Louise Kristine Vigsnæs, Nigel Baldwin, Christel Jørgensen   +8 more
wiley   +1 more source

Hypothyroidism consequent to thyroidectomy is associated with elevated remnant lipoproteins and cholesterol enrichment of triglyceride-rich lipoproteins: an observational study. [PDF]

Lipids Health Dis
Post A, Links MH, Zandee WT, Connelly MA, Links TP, Dullaart RPF.   +5 more
europepmc   +1 more source

Pharmacokinetics and Safety of Fenofibrate in Participants with Mild Hepatic Impairment or with Advanced Fibrosis due to Metabolic‐Associated Fatty Liver Disease

The Journal of Clinical Pharmacology, EarlyView.
Abstract Fenofibrate is contraindicated in patients with advanced hepatic fibrosis due to limited clinical data. We evaluated the pharmacokinetics and safety of fenofibrate in participants with mild hepatic impairment (phase 1 study) or advanced fibrosis due to metabolic‐associated fatty liver disease (MAFLD; phase 2a study).
Islam R. Younis, Elijah J. Weber, Cara Nelson, Ann R. Qin, Timothy R. Watkins, Ahmed A. Othman   +5 more
wiley   +1 more source

The significance of ANGPTL3 and ANGPTL4 proteins in the development of dyslipidemia in Type 2 diabetes mellitus. [PDF]

J Family Med Prim Care
Swarnakar R, Sahu D, Bahinipati J, Pradhan T, Meher D, Sarangi R, Mahapatra S.   +6 more
europepmc   +1 more source