Results 251 to 260 of about 451,388 (320)

Icosapent ethyl-induced lipoprotein remodeling and its impact on cardiovascular disease risk markers in normolipidemic individuals. [PDF]

JCI Insight
Äikäs L, Kovanen PT, Lorey MB, Laaksonen R, Holopainen M, Ruhanen H, Käkelä R, Jauhiainen M, Hermansson M, Öörni K.   +9 more
europepmc   +1 more source

A standard blood bank donation improves cardiometabolic health of donors: A double‐blind randomised controlled trial

British Journal of Haematology, EarlyView.
The upper panel illustrates the study design, including recruitment, randomisation, intervention and oral glucose tolerance tests (OGTTs) conducted 2 weeks before and after. The lower panel shows reductions in serum ferritin associated with lower 2‐h OGTT glucose and lower glucose area under the curve (AUC).
Diego Mora‐Gonzalez, Alfonso Moreno‐Cabañas, Lucía Gonzalez García, Ana Isabel Cobo‐Cuenca, Maria del Carmen Muñoz‐Turrillas, Ricardo Mora‐Rodriguez, Felix Morales‐Palomo   +6 more
wiley   +1 more source

Association Between Remnant Cholesterol and Endometriosis Findings from NHANES 1999-2006. [PDF]

Int J Womens Health
Su L, Wang X, Zhang J, Xu R, Ren Y, Wang S.   +5 more
europepmc   +1 more source

The use of different types of networks, alone and in combination, for drug target identification

British Journal of Pharmacology, EarlyView.
Current therapeutic approaches often focus on targeting clinical symptoms or peripheral phenotypes rather than the underlying molecular mechanisms, or endophenotypes, that drive diseases. While symptom‐based drugs can alleviate discomfort, they do not necessarily alter disease progression and may overlook opportunities for prevention or early ...
Paolo Parini
wiley   +1 more source

Sources of essential lipids for Mycoplasma pneumoniae via P116 to target liver and atherosclerotic lesions. [PDF]

Nat Commun
Vizarraga D, Marcos M, Rotllan N, Martín J, Santos D, Camacho M, Soto B, Velasco-Reniu L, Guerra P, Pareja F, Collantes M, Wu W, Rodríguez-Arce I, Serrano L, Piñol J, Fita I, Escolà-Gil JC.   +16 more
europepmc   +1 more source

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

British Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli, Emanuela Micioni Di Bonaventura, Giacomo Einaudi, Gustavo Provensi, Alessia Costa, Claudio D'Addario, Carlo Cifani, Maria Vittoria Micioni Di Bonaventura   +7 more
wiley   +1 more source

Very-Low-Density Lipoproteins Quantity but Not Composition Is Altered in Normotriglyceridemic Subjects with Elevated Lipoprotein (a) Level. [PDF]

Int J Mol Sci
Wieczorek-Breitzke E, Feliksiak M, Kuchta A, Jankowski M, Ćwiklińska A.   +4 more
europepmc   +1 more source

The potential for biased signalling in the P2Y receptor family of GPCRs

British Journal of Pharmacology, EarlyView.
The purinergic receptor family is primarily activated by nucleotides, and contains members of both the G protein coupled‐receptor (GPCR) superfamily (P1 and P2Y) and ligand‐gated ion channels (P2X). The P2Y receptors are widely expressed in the human body, and given the ubiquitous nature of nucleotides, purinergic signalling is involved with a plethora
Claudia M. Sisk, Simon Pitchford, Graham Ladds   +2 more
wiley   +1 more source

Lipoprotein-Specific Fatty Acid Profiles in Familial Hypercholesterolemia: Associations with Cardiovascular History and Dietary Patterns. [PDF]

Nutrients
López-Yerena A, Arroyo-Olivares R, Santisteban V, Muñoz-Garcia N, Estruch R, Mata P, Badimon L, Padro T.   +7 more
europepmc   +1 more source