Results 31 to 40 of about 91,535 (288)
Adsorption of High Density Lipoproteins (HDL) on Solid Surfaces [PDF]
The adsorption of high density lipoproteins (HDL) on polyethylene (PE), poly(2-hydroxyethyl methacrylate) (poly(HEMA)), polyesterurethane (PU), Biomer, and mica surfaces was studied. The adsorption of HDL from a single protein solution and a plasma solution on the surfaces showed that the amount of adsorbed HDL was not related to the hydrophobicity (or
Kees van der Werf+7 more
openaire +3 more sources
High-density lipoprotein (HDL) contributes to lipolysis of triglyceride-rich lipoprotein (TGRL) by lipoprotein lipase (LPL) via acquirement of surface lipids, including free cholesterol (FC), released upon lipolysis. According to the reverse remnant-cholesterol transport (RRT) hypothesis recently developed by us, acquirement of FC by HDL is reduced at ...
Schekatolina, Svetlana+5 more
openaire +5 more sources
High-density lipoproteins (HDL): Novel function and therapeutic applications
The failure of high-density lipoprotein (HDL)-raising agents to reduce cardiovascular disease (CVD) together with recent findings of increased cardiovascular mortality in subjects with extremely high HDL-cholesterol levels provide new opportunities to revisit our view of HDL. The concept of HDL function developed to explain these contradictory findings
Darabi, Maryam, Kontush, Anatol
openaire +4 more sources
This narrative review focuses on the role of cholesteryl ester transfer protein (CETP) and peripheral lipoproteins in the vascular contributions to cognitive impairment and dementia (VCID).
Tetiana Poliakova, Cheryl L. Wellington
doaj +1 more source
High-density lipoprotein (HDL) metabolism and bone mass [PDF]
It is well appreciated that high-density lipoprotein (HDL) and bone physiology and pathology are tightly linked. Studies, primarily in mouse models, have shown that dysfunctional and/or disturbed HDL can affect bone mass through many different ways.
Dionysios J. Papachristou+3 more
openaire +3 more sources
Reduction of circulating cholesterol and apolipoprotein levels during sepsis [PDF]
Sepsis with multiple organ failure is frequently associated with a substantial decrease of cholesterol levels. This decrease of cholesterol is strongly associated with mortality suggesting a direct relation between inflammatory conditions and altered ...
Alvarez C+27 more
core +1 more source
High density lipoproteins (HDLs) and atherosclerosis; the unanswered questions
The concentration of high density lipoprotein-cholesterol (HDL-C) has been found consistently to be a powerful negative predictor of premature coronary heart disease (CHD) in human prospective population studies. There is also circumstantial evidence from human intervention studies and direct evidence from animal intervention studies that HDLs protect ...
Barter, P+3 more
openaire +4 more sources
Hepatitis C virus relies on lipoproteins for its life cycle [PDF]
Hepatitis C virus (HCV) infects over 150 million people worldwide. In most cases, HCV infection becomes chronic causing liver disease ranging from fibrosis to cirrhosis and hepatocellular carcinoma.
Alonzi, Tonino+5 more
core +1 more source
Suppression of Endothelial Cell Apoptosis by High Density Lipoproteins (HDL) and HDL-associated Lysosphingolipids [PDF]
Apoptotic cell death following injury of vascular endothelium is assumed to play an important role in the pathogenesis of atherosclerosis. In this report, we demonstrate that high density lipoproteins (HDL), a major anti-atherogenic lipoprotein fraction, protect endothelial cells against growth factor deprivation-induced apoptosis.
Bodo Levkau+7 more
openaire +3 more sources
High Density Lipoproteins Inhibit Oxidative Stress-Induced Prostate Cancer Cell Proliferation [PDF]
Recent evidence suggests that oxidative stress can play a role in the pathogenesis and the progression of prostate cancer (PCa). Reactive oxygen species (ROS) generation is higher in PCa cells compared to normal prostate epithelial cells and this ...
Botta, Margherita+8 more
core +2 more sources