Results 61 to 70 of about 91,535 (288)

Biophysical characterization of the interaction of high‐density lipoprotein (HDL) with endotoxins [PDF]

European Journal of Biochemistry, 2002
The interaction of bacterial endotoxins [lipopolysaccharide (LPS) and the ‘endotoxic principle’ lipid A], with high‐density lipoprotein (HDL) from serum was investigated with a variety of physical techniques and biological assays. HDL exhibited an increase in the gel to liquid crystalline phase transition temperature Tc and a rigidification of the acyl
Brandenburg, Klaus, Jürgens, Gudrun, Andrä, Jörg, Lindner, Buko, Koch, Michel H. J., Blume, Alfred, Garidel, Patrick   +6 more
openaire   +4 more sources

The Effect of Chia Seeds on High-Density Lipoprotein (HDL) Cholesterol

Cureus, 2023
Chia seeds are touted as a healthy food capable of providing a beneficial effect on high-density lipoprotein (HDL) cholesterol. Similar claims have been made for oats in various forms, claiming that they improve cholesterol or are in some way "heart healthy." This study aims to demonstrate the effect of daily consumption of chia seeds, if any, on HDL ...
Dickens, Brian, Sassanpour, Mana, Bischoff, Evan L   +2 more
openaire   +2 more sources

Pyruvate Carboxylase in Macrophages Aggravates Atherosclerosis by Regulating Metabolism Reprogramming to Promote Inflammatory Responses Through the Hypoxia‐Inducible Factor‐1 Signaling Pathway

Advanced Science, EarlyView.
This study investigates the role of macrophage pyruvate carboxylase (PC) in atherosclerosis (AS) demonstrating that PC upregulation in macrophages promotes metabolism reprogramming to enhance inflammatory responses via the HIF‐1 signaling pathway.
Ling‐Na Zhao, Rui‐Ling Wang, Ran‐Xin Liu, Meng‐Ru Zheng, Li Zhao, Bao‐Feng Li, Jia‐Le Li, De‐Shen Liu, Xiao‐Xia He, Qin‐Bao Peng, Kai Li, Tian‐Xiao Lin, Ying‐Ying Liu, Sheng‐Ping He, Jun Lu, Shao‐Yi Zheng, Xiu Liu, Fang‐Ze Huang   +17 more
wiley   +1 more source

High density lipoprotein-induced cardiac prostacyclin synthesis in vitro: relationship to cardiac arachidonate mobilization.

Journal of Lipid Research, 1988
The objectives of this study were to characterize the effects of plasma lipoproteins on prostacyclin (PGI2) production by the Langendorff-perfused rabbit heart, and to determine the mechanism of lipoprotein-induced cardiac PGI2 production.
W A Van Sickle, H G Wilcox, K U Malik, A Nasjletti   +3 more
doaj  

Isolation and Characterization of a Cellular Protein-Lipid Complex from Ascites Fluid Caused by Various Neoplasms [PDF]

, 1986
High concentrations of lipids in ascites fluid caused by peritoneal carcinomatosis have been described recently. Since their nature has not yet been clarified, we isolated ascitic lipids from 25 patients with various neoplasms for further ...
Caselmann, Wolfgang H., Jüngst, Dieter
core  

Anti-inflammatory and antioxidant properties of HDLs are impaired in type 2 diabetes. [PDF]

, 2011
ObjectiveIn mice, 4F, an apolipoprotein A-I mimetic peptide that restores HDL function, prevents diabetes-induced atherosclerosis. We sought to determine whether HDL function is impaired in type 2 diabetic (T2D) patients and whether 4F treatment improves
Boldrini, Beatrice, Ferrannini, Ele, Fogelman, Alan M, Imaizumi, Satoshi, Morgantini, Cecilia, Natali, Andrea, Navab, Mohamad, Reddy, Srinivasa T   +7 more
core   +1 more source

Nucleotides as an Anti‐Aging Supplementation in Older Adults: A Randomized Controlled Trial (TALENTs study)

Advanced Science, EarlyView.
The TALENTs randomized controlled trial evaluates the potential of nucleotides supplementation as an anti‐aging intervention in older adults. After 19 weeks, nucleotides supplementation significantly reduces DNA methylation age, suggesting a delay in epigenetic aging, and improves insulin sensitivity without severe adverse events.
Shuyue Wang, Lixia Song, Rui Fan, Qianqian Chen, Ruisheng Fu, Mei You, Yuxiao Wu, Meng Cai, Yong Li, Meihong Xu   +9 more
wiley   +1 more source

Thematic review series: Patient-Oriented Research. What have we learned about HDL metabolism from kinetics studies in humans?

Journal of Lipid Research, 2006
Plasma measurements of lipids, lipoproteins, and apolipoproteins provide information on the static levels of these fractions without providing key information on the dynamic fluxes of lipoproteins in the circulation.
Shirya Rashid, Bruce W. Patterson, Gary F. Lewis   +2 more
doaj  

Artificial High Density Lipoprotein Nanoparticles in Cardiovascular Research

Molecules, 2019
Lipoproteins are endogenous nanoparticles which are the major transporter of fats and cholesterol in the human body. They play a key role in the regulatory mechanisms of cardiovascular events.
Karin Kornmueller, Ivan Vidakovic, Ruth Prassl   +2 more
doaj   +1 more source

Apolipoprotein E and Atherosclerosis: From Lipoprotein Metabolism to MicroRNA Control of Inflammation. [PDF]

, 2018
Apolipoprotein (apo) E stands out among plasma apolipoproteins through its unprecedented ability to protect against atherosclerosis. Although best recognized for its ability to mediate plasma lipoprotein clearance in the liver and protect against ...
Hasty, Hui, Hussain, Lin, Mahley, Pepe, Roselaar   +6 more
core   +2 more sources