Results 281 to 290 of about 106,428 (294)

The Emerging Role of Lipoproteins in Atherogenesis: Beyond LDL Cholesterol

Seminars in Vascular Medicine, 2004
Low-density lipoprotein cholesterol has a well-established role in atherogenesis and the development of coronary heart disease. However, despite effective lowering of low-density lipoprotein cholesterol, many patients continue to have cardiovascular events.
Pia Lundman, Pia Lundman, Stephen J. Nicholls   +2 more
openaire   +3 more sources

Effects of postmenopausal hormone replacement therapy on lipoproteins including lipoprotein(a) and LDL subfractions

Atherosclerosis, 1996
The purpose of this study was to examine the effects on lipoprotein risk markers for CHD of oestradiol given alone and in combination with the androgenic progestogen, norethisterone. Eighty postmenopausal women were randomly allocated to receive oestradiol (2 mg/day) alone or with continuous norethisterone (1 mg/day).
C. D. Fletcher, AL Calder, David M. Hart, A Brown, E. Farish, JF Barnes, K. Spowart   +6 more
openaire   +3 more sources

Lipoprotein (LDL and HDL) Oxidation in Diabetes Mellitus

2013
Diabetes mellitus, in general, and hyperglycemia, in particular, are both linked to premature and accelerated atherogenesis. This is mediated via lipid modifications both quantitatively (mostly increased levels of serum VLDL and decreased HDL concentrations) and qualitatively (lipoproteins oxidation), leading to the accumulation of macrophage foam ...
Michael Aviram, Tony Hayek, Marielle Kaplan   +2 more
openaire   +2 more sources

Low density lipoprotein (LDL), atherosclerosis and antioxidants

Biotechnology and Bioprocess Engineering, 2000
A crucial and causative role in the pathogenesis of atherosclerosis is believed to be the oxidative modification of low density lipoprotein (LDL). The oxidation of LDL involves released free radical driven lipid peroxidation. Several lines of evidence support the role of oxidized LDL in atherogenesis.
openaire   +2 more sources

Oxidation of low density lipoprotein (LDL) by cells

1995
Is there a need to study the cellular mechanism(s) of oxidation of LDL? If antioxidants are safe and effective even at relatively high doses in retarding the progression of experimental atherosclerosis, why is it important to study the specific mechanism(s) by which oxidative process may be initiated?
openaire   +2 more sources

Asociation of PCSK9 with Low Density Lipoproteins (LDL) in the Regulation of LDL-Cholesterol Levels [PDF]

, 2015
Proprotein Convertase Subtilisin / Kexin Type-9 (PCSK9) has emerged as a major regulator of plasma cholesterol levels. PCSK9 is secreted mainly from the liver and circulates as a plasma protein. PCSK9 binds cell surface low-density lipoprotein (LDL) receptors and mediates their degradation upon endocytosis in the liver.
openaire   +2 more sources

Lipoproteins, HDL/LDL

2004
David L. Williams, Fayanne E. Thorngate
openaire   +2 more sources

Transport of LDL in plasma and lipoprotein metabolism

Atherosclerosis, 1994
Roger Savonen, Magnus Hultin, Thomas Olivecrona, O. Chevreuil, Gunilla Olivecrona   +4 more
openaire   +2 more sources

Interaction of lipoprotein(a) with the platelet LDL receptor

Atherosclerosis, 1995
R. Fernández, J. Pedreño
openaire   +2 more sources

Lipoprotein levels and oxidizability of LDL during long-term LDL-apheresis

Atherosclerosis, 1994
Pierre N.M. Demacker, Abraham A. Kroon, A.F.H. Stalenhoef   +2 more
openaire   +2 more sources