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Causes and Consequences of Hypertriglyceridemia
Elevations in plasma triglyceride are the result of overproduction and impaired clearance of triglyceride-rich lipoproteins—very low-density lipoproteins (VLDL) and chylomicrons. Hypertriglyceridemia is characterized by an accumulation in the circulation
Chris J. Packard+2 more
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Triglycerides are carried in the bloodstream as part of very low-density lipoproteins (VLDLs) and chylomicrons, which represent the triglyceride-rich lipoproteins.
Lei Deng+5 more
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Apolipoprotein C1 (apoC1) is a small size apolipoprotein whose exact role is not totally clarified but which seems to modulate significantly the metabolism of lipoproteins.
Alexia Rouland+5 more
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Hepatic Golgi lipoproteins: precursors to plasma lipoproteins in hypercholesterolemic rats
Two classes of nascent lipoproteins can be isolated from Golgi apparatus-rich fractions of liver from hypercholesterolemic rats. Golgi very low density lipoproteins (VLDL, d less than 1.006 g/ml) are enriched in cholesteryl esters and are similar in many
L L Swift, P D Soulé, V S LeQuire
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The clinical evaluation of lipid metabolism in equids is often limited to the measurement of total cholesterol and triglyceride concentrations. This provides a limited picture of metabolic state and general health, given the continuous exchange of lipid ...
Erin L. Goodrich, Erica Behling-Kelly
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The ability of rat intestine and liver to synthesize the various apoproteins of plasma lipoproteins was investigated. After the individual isolated organs were perfused with blood containing [3H]lysine, chylomicrons plus very low density lipoproteins ...
Herbert G. Windmueller+2 more
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Two procedures were used to isolate hepatocytic Golgi fractions from rat liver. One procedure yields a light Golgi fraction (GF1 + 2) and the other “intact” stacks of cisternae.
RL Hamilton, A Moorehouse, RJ Havel
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Lipoprotein metabolism in the suckling rat: characterization of plasma and lymphatic lipoproteins.
Suckling rat plasma contains (in mg/dl): chylomicrons (85 +/- 12); VLDL (50 +/- 6); LDL (200 +/- 23); HDL1 (125 +/- 20); and HDL2 (220 +/- 10), while lymph contains (in mg/dl): chylomicrons (9650 +/- 850) and VLDL (4570 +/- 435) and smaller amounts of ...
G J Fernando-Warnakulasuriya+3 more
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Effect of very low-density lipoproteins on lipid transfer in incubated serum
Incubation of human serum solutions low in glyceride content for 16 hr resulted in a net increase of cholesterol esters in all three major human serum lipoprotein classes, namely the very low-density lipoproteins of d < 1.006 (VLDL), low-density ...
A.V. Nichols, L. Smith
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Secondary structure in very low density and intermediate density lipoproteins of human serum.
We have studies the secondary structures of the protein moieties of very low density lipoproteins (VLDL) and intermediate density lipoproteins (IDL) of human serum by circular dichroism (CD).
G C Chen, J P Kane
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