Results 101 to 110 of about 191,701 (337)
Abstract Background Neuroendocrine carcinomas of the gastrointestinal tract (GI‐NECs) remain a disease of grim prognosis with limited therapeutic options. Their molecular characteristics are still undefined. This study aimed to explore the underlying genetic basis and heterogeneity of GI‐NECs.
Huanwen Wu+13 more
wiley +1 more source
Abdominal Obesity, Dyslipidemia and Blood Pressure
Fat stored in the abdominal region is resistant to insulin, increased degradation of triglycerides to fatty acids. The increased availability of fatty acids in the liver favors the formation of very low density lipoproteins and the resulting ...
Pedro Enrique Miguel Soca
doaj +2 more sources
Heterogeneity of human very low density lipoproteins by gel filtration chromatography
Very low density lipoproteins were separated by gel filtration on Sepharose 4B. A decrease in mean particle diameter and flotation rate was seen with increasing elution volumes.
Steven H. Quarfordt+3 more
doaj
OBJECTIVE: To analyze associations between levels of physical activity, cardiorespiratory fitness, dietary content, and risk factors that cause a predisposition towards cardiovascular disease.
Dartagnan Pinto Guedes+1 more
doaj +1 more source
Bayesian modelling for binary outcomes in the Regression Discontinuity Design [PDF]
The Regression Discontinuity (RD) design is a quasi-experimental design which emulates a randomised study by exploiting situations where treatment is assigned according to a continuous variable as is common in many drug treatment guidelines. The RD design literature focuses principally on continuous outcomes.
arxiv
Decoding Blastocystis‐Driven Mechanisms in Gut Microbiota and Host Metabolism
Blastocystis, a prevalent gut microbe, interacts with the host through metabolic and immune pathways, influencing cardiometabolic health. This perspective explores its role in modulating short‐chain fatty acid production, tryptophan metabolism, and immune signaling, potentially impacting cholesterol absorption, glucose metabolism, and vascular health ...
Lei Deng, Kevin SW Tan
wiley +1 more source
Lipoprotein metabolism in the suckling rat: characterization of plasma and lymphatic lipoproteins.
Suckling rat plasma contains (in mg/dl): chylomicrons (85 +/- 12); VLDL (50 +/- 6); LDL (200 +/- 23); HDL1 (125 +/- 20); and HDL2 (220 +/- 10), while lymph contains (in mg/dl): chylomicrons (9650 +/- 850) and VLDL (4570 +/- 435) and smaller amounts of ...
G J Fernando-Warnakulasuriya+3 more
doaj
Contextualizing selection bias in Mendelian randomization: how bad is it likely to be? [PDF]
Selection bias affects Mendelian randomization investigations when selection into the study sample depends on a collider between the genetic variant and confounders of the risk factor-outcome association. However, the relative importance of selection bias for Mendelian randomization compared to other potential biases is unclear.
arxiv
RACK7 Interacts with PRC2 Complex to Regulate Astrocyte Development
The study investigates the role of RACK7 in brain development using a conditional knockout mouse model. RACK7 deficiency results in developmental defects and abnormal astrocyte development by disrupting H3K27me3 chromatin binding. The underlying mechanism involves RACK7 interacting with the PRC2 complex to regulate the genomic localization of SUZ12 and
Fangfang Jiao+9 more
wiley +1 more source
A method to measure apolipoprotein B radioactivity in whole blood plasma is described that is suitable for routine use in kinetic experiments in vivo.
N Yamada, R J Havel
doaj