Results 101 to 110 of about 319,032 (338)

Hyperlipoproteinemia in fasting ponies

Journal of Lipid Research, 1972
Ponies fasted for up to 8 days showed, both by agarose electrophoresis and preparative ultracentrifugation, the appearance of a pre-β-migrating, very low density lipoprotein fraction in plasma.
M.D. Morris, D.B. Zilversmit, H.F. Hintz
doaj   +1 more source

Digitonin‐Loaded Nanoscale Metal–Organic Framework for Mitochondria‐Targeted Radiotherapy‐Radiodynamic Therapy and Disulfidptosis

Advanced Materials, EarlyView.
A mitochondria‐targeted cationic nanoscale metal organic framework shows strong radiotherapy‐radiodynamic therapy effects and selectively releases digitonin in acidic tumor microenvironments to induce disulfidptosis of cancer cells and downregulate immune checkpoints in cancer and T cells, thereby eliciting strong antitumor immunity to effectively ...
Wenyao Zhen, Yingjie Fan, Tomas Germanas, Langston Tillman, Jinhong Li, Abigail L. Blenko, Ralph R. Weichselbaum, Wenbin Lin   +7 more
wiley   +1 more source

Chylomicron remnant cholesteryl esters as the major constituent of very low density lipoproteins in plasma of cholesterol-fed rabbits

Journal of Lipid Research, 1977
Feeding rabbits 500 mg of cholesterol daily for 4 to 15 days greatly increased the concentration of esterified cholesterol in lipoproteins of d < 1.006 g/ml.
A C Ross, D B Zilversmit
doaj   +1 more source

Evolving lipoprotein risk factors: lipoprotein(a) and oxidized low-density lipoprotein [PDF]

Clinical Chemistry, 1998
Abstract Cardiovascular disease is the leading cause of morbidity and mortality in Westernized populations. Evolving lipoprotein risk factors include LDL oxidation and lipoprotein(a) [lp(a)]. Several lines of evidence support a role for oxidatively modified LDL in atherogenesis and its in vivo existence.
openaire   +3 more sources

Plaque‐Targeted Delivery of Fluoride‐Free MXene Nanozyme for Alleviating Atherosclerosis via Sonocatalytic Therapy

Advanced Materials, EarlyView.
This work has developed a dual enzyme‐mimicking and ultrasound‐responsive Nb2C‐Pt@HA‐PEG nanozyme. ROS‐eliminating and anti­inflammatory capability of Nb2C‐Pt@HA‐PEG under US irradiation are demonstrated on macrophages and endothelial cells in vitro. Nb2C‐Pt@HA‐PEG‐mediated sonocatalytic therapy exerts an outstanding anti‐atherosclerosis efficacy by ...
Qianqian Bai, Xinyue Lao, Sin‐Yi Pang, Yifei Zhao, Yuan Liu, Xiao Yu Tian, Jianhua Hao   +6 more
wiley   +1 more source

Apolipoprotein E-deficient lipoproteins induce foam cell formation by downregulation of lysosomal hydrolases in macrophages

Journal of Lipid Research, 2007
Apolipoprotein E (apoE) deficiency has been suggested to induce foam cell formation. Using lipoproteins obtained from wild-type mice and apoE-deficient mice expressing apoB-48 but not apoB-100, we studied apoE-deficient lipoprotein-induced changes in ...
DongFang Wu, Chakradhari Sharan, Hong Yang, J. Shawn Goodwin, Lichun Zhou, Gregory A. Grabowski, Hong Du, ZhongMao Guo   +7 more
doaj   +1 more source

Relationship Between Physical Conditioning and Plasma High Density Lipoprotein-Cholesterol Concentration [PDF]

, 1983
Five subjects (three females and two males) took part in an exercise regimen in order to determine if aerobic exercise results in an increase in high-density lipoprotein-cholesterol levels (HDL-C) in the plasma.
Baeyens, Dennis A., Morgans, Leland F., Morris, Manford D.   +2 more
core   +2 more sources

Familial hypercholesterolemia: The Italian Atherosclerosis Society Network (LIPIGEN) [PDF]

, 2017
Primary dyslipidemias are a heterogeneous group of disorders characterized by abnormal levels of circulating lipoproteins. Among them, familial hypercholesterolemia is the most common lipid disorder that predisposes for premature cardiovascular disease ...
Angelico, F., Arca, M, Averna, M., Bertolini, S, Calandra, S, Casula, M, Catapano, Al, Cefalù, Ab, Del Ben, M., Lipigen, Group, Maranghi, M, Montali, A., Noto, D, Tarugi, P.   +13 more
core   +1 more source

Dendrimers Improve Apolipoprotein Nanoparticle mRNA Delivery to Immune Cells

Advanced Materials, EarlyView.
Apolipoprotein nanoparticle (aNP) platform technology efficiently delivers RNA to immune cells following systemic administration. Here, it is demonstrated that incorporating polyvalent ionizable cationic dendrimers in aNPs enables robust mRNA complexation and functional delivery.
Mirre M. Trines, Daniek Hoorn, Stijn R.J. Hofstraat, Robby C. Zwolsman, Tom Anbergen, Iris Versteeg, Yuri van Elsas, Jeroen Deckers, Merel M.A. Hendrikx, Teun Kleuskens, Youssef B. Darwish, Gijs W.B. Ros, Sjoerd F. Dijkstra, Bram Priem, Matt Timmers, P. Michel Fransen, Maarten J. Pouderoijen, Bas F.M. de Waal, E.W. Meijer, Thijs J. Beldman, Yohana C. Toner, Ewelina Kluza, Willem J.M. Mulder, Henk M. Janssen, Roy van der Meel   +24 more
wiley   +1 more source

Impaired receptor-mediated catabolism of low density lipoproteins in fasted rabbits.

Journal of Lipid Research, 1984
Plasma cholesterol levels of New Zealand white rabbits, fasted for 9 days, increased 4-fold owing to elevated levels of low density lipoproteins and intermediate density lipoproteins.
J B Stoudemire, G Renaud, D M Shames, R J Havel   +3 more
doaj   +1 more source