Results 111 to 120 of about 191,701 (337)
The heparan sulfate and its diverse biological activities
Heparan sulfate (HS) is one of the most common glycosaminoglycan (GAG) in mammals. It is composed of relatively simple disaccharide subunits, which, by further modification, such as sulfation and epimerization, potentially offer huge diversity in ...
Kaznowska-Bystryk Iwona
doaj +1 more source
LIPOPROTEIN PATTERNS OF SERUM OBTAINED BY ZONE ELECTROPHORESIS [PDF]
Henry G. Kunkel, Robert J. Slater
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Network‐based risk stratification of people living with HIV (PWH) on prolonged therapy using multi‐omics data identifies 44% of the patients are at risk of immunometabolic complications. A senescence‐associated myeloid cell‐driven plasma microenvironment drives immunometabolic dysregulation in at‐risk PWH.
Flora Mikaeloff+32 more
wiley +1 more source
Metabolism of lipoproteins containing apolipoprotein B in hepatic lipase-deficient mice
Mice lacking hepatic lipase have been reported to express mild hyperlipidemia characterized by increased concentrations of large high density lipoproteins, but normal concentrations of lipoproteins containing apolipoprotein B.
Shiqiang Qiu+5 more
doaj
3D culture of MSCs upregulates gene expression of matrix metalloproteinases (MMPs), growth factors (GFs), and increases the production of extracellular vesicles (EVs). Proteomic analysis reveals 642 upregulated proteins in 3D‐EVs, including HGF. These 3D‐EVs, enriched with HGF, protect lung epithelial cells from apoptosis and barrier damage in septic ...
Yong Chen+9 more
wiley +1 more source
Exosomes and their roles in the chemoresistance of pancreatic cancer
Despite the development of multiple promising chemotherapeutic agents as recommended first‐line treatment for PC, the therapeutic efficacy is largely limited by unwanted drug resistance.Exploring the relation between exosomes and chemoresistance may be conducive to understanding molecular mechanisms and taking effective measures to reduce the ...
Yubin Pan+4 more
wiley +1 more source
The proton NMR spectra of the N-methyl choline region of normal and lecithin:cholesterol acyltransferase (LCAT)-deficient lipoproteins and of egg yolk phosphatidylcholine-cholesterol 55:45 (mol %) vesicle mixtures have been examined in the presence and ...
Y I Parmar+4 more
doaj
ULTRACENTRIFUGAL CHARACTERIZATION OF THE LIPOPROTEIN SPECTRUM IN OBSTRUCTIVE JAUNDICE: STUDIES OF SERUM LIPID RELATIONSHIPS IN INTRA- AND EXTRAHEPATIC BILIARY OBSTRUCTION 1 [PDF]
Robert H. Furman+4 more
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FABP4 as a Mediator of Lipid Metabolism and Pregnant Uterine Dysfunction in Obesity
Obesity during late pregnancy contributes to uterine smooth muscle dysfunction, but the underlying mechanisms are unclear. This study identifies fatty acid binding protein 4 (FABP4) as a key player in the process, mediating excessive fatty acid uptake, lipid accumulation, and mitochondrial dysfunction in myometrial cells. FABP4 could be a novel uterine
Xuan Li+11 more
wiley +1 more source