Results 131 to 140 of about 309,210 (382)

Antibodies to low-density lipoproteins modified by malonic dialdehyde: contents in blood and role in atherogenesis

open access: yesМедицинская иммунология
In this work, we determined the content of antibodies to low-density lipoproteins modified by malondialdehyde, the concentration of circulating immune complexes cholesterol and oxidized low-density lipoproteins in the blood of healthy individuals and ...
A. A. Ivanova   +2 more
doaj   +1 more source

Blood lipoproteins shape the phenotype and lipid content of early atherosclerotic lesion macrophages: a dual-structured mathematical model [PDF]

open access: yesarXiv
Macrophages in atherosclerotic lesions exhibit a spectrum of behaviours or phenotypes. The phenotypic distribution of monocyte-derived macrophages (MDMs), its correlation with MDM lipid content, and relation to blood lipoprotein densities are not well understood.
arxiv  

EFFECT OF THE LEVEL AND TYPE OF DIETARY FAT ON THE METABOLISM OF CHOLESTEROL AND BETA LIPOPROTEINS IN THE CEBUS MONKEY [PDF]

open access: bronze, 1956
Oscar W. Portman   +5 more
openalex   +1 more source

DNA‐PKcs‐Driven YAP1 Phosphorylation and Nuclear Translocation: a Key Regulator of Ferroptosis in Hyperglycemia‐Induced Cardiac Dysfunction in Type 1 Diabetes

open access: yesAdvanced Science, EarlyView.
In the context of chronic hyperglycemia, a DDR is initiated, leading to the pathological activation of DNA‐PKcs in the diabetic heart. This activated DNA‐PKcs directly interacts with and phosphorylates YAP1 at Thr226, thereby increasing the nuclear expression of YAP1.
Junyan Wang   +10 more
wiley   +1 more source

Heterogeneity of human very low density lipoproteins by gel filtration chromatography

open access: yesJournal of Lipid Research, 1972
Very low density lipoproteins were separated by gel filtration on Sepharose 4B. A decrease in mean particle diameter and flotation rate was seen with increasing elution volumes.
Steven H. Quarfordt   +3 more
doaj  

Regression Discontinuity Designs: A Decision Theoretic Approach [PDF]

open access: yesarXiv, 2016
The regression discontinuity design (RDD) is a quasi-experimental design that can be used to identify and estimate the causal effect of a treatment using observational data. In an RDD, a pre-specified rule is used for treatment assignment, whereby a subject is assigned to the treatment (control) group whenever their observed value of a specific ...
arxiv  

Determination of Serum Lipoproteins by Paper Electrophoresis after Preliminary Staining with Sudan Black-B [PDF]

open access: bronze, 1958
Eugene L. Kanabrocki   +5 more
openalex   +1 more source

Targeting Splenic Myeloid Cells with Nanobiologics to Prevent Postablative Pancreatic Cancer Recurrence via Inducing Antitumor Peripheral Trained Immunity

open access: yesAdvanced Science, EarlyView.
Using a preclinical pancreatic cancer model, we identified that tumor progression restructures splenic immunity via myeloid cell expansion. MDCa@RBC‐Alipo nanobiologics were engineered to epigenetically and metabolically reprogram splenic myeloid cells, alleviating post‐ablation immunosuppression.
Shengbo Wu   +12 more
wiley   +1 more source

Metabolism of lipoproteins containing apolipoprotein B in hepatic lipase-deficient mice

open access: yesJournal of Lipid Research, 1998
Mice lacking hepatic lipase have been reported to express mild hyperlipidemia characterized by increased concentrations of large high density lipoproteins, but normal concentrations of lipoproteins containing apolipoprotein B.
Shiqiang Qiu   +5 more
doaj  

Bayesian modelling for binary outcomes in the Regression Discontinuity Design [PDF]

open access: yesarXiv, 2016
The Regression Discontinuity (RD) design is a quasi-experimental design which emulates a randomised study by exploiting situations where treatment is assigned according to a continuous variable as is common in many drug treatment guidelines. The RD design literature focuses principally on continuous outcomes.
arxiv  

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