Results 131 to 140 of about 587,996 (382)

Effect of diet on the cholesterol ester composition of liver and of plasma lipoproteins in the rat

Journal of Lipid Research, 1965
The relationship between the cholesterol ester composition of the liver and the plasma lipoproteins was studied in groups of rats maintained for 5–11 weeks on the following diets: (I) rat pellets, (II) rat pellets with added olive oil and cholesterol ...
Lewis I. Gidez, Paul S. Roheim, Howard A. Eder   +2 more
doaj   +1 more source

Constitutional and environmental factors related to serum lipid and lipoprotein levels [PDF]

Serum lipoproteins and lipids in 657 human males correlated to multiple constitutional and environmental ...
Graybiel, A., Harlan, W. R., Jr., Mitchell, R. E., Oberman, A., Wherry, R. J., Jr.   +4 more
core   +1 more source

Disengaging the Engine: Histone Deacetylases 1 and 2‐Mediated Acetylation of Hexokinase‐2 Regulates Energy Metabolism in Microglia Following Intracerebral Hemorrhage

Advanced Science, EarlyView.
This study demonstrates that HDAC1/2 knockout in microglia alleviates neurological deficits, preserves white matter, and accelerates hematoma clearance after ICH. HDAC1/2 inhibition reduces HK2 acetylation, shifts metabolism from glycolysis to fatty acid oxidation, reduces inflammation, and enhances phagocytosis.
Zhiwen Jiang, Heng Yang, Xinjie Gao, Zengyu Zhang, Ruiyuan Weng, Yuchao Fei, Jiabin Su, Hanqiang Jiang, Wei Ni, Yuxiang Gu   +9 more
wiley   +1 more source

Abdominal Obesity, Dyslipidemia and Blood Pressure

Revista Finlay, 2015
Fat stored in the abdominal region is resistant to insulin, increased degradation of triglycerides to fatty acids. The increased availability of fatty acids in the liver favors the formation of very low density lipoproteins and the resulting ...
Pedro Enrique Miguel Soca
doaj   +2 more sources

Analyzing the molecular mechanism of lipoprotein localization in Brucella

Frontiers in Microbiology, 2015
Bacterial lipoproteins possess comprehensive structure and functionality, ranging from bacterial physiology to pathogenic processes. As such many lipoproteins, originating from Brucella are exploited as potential vaccines to countermeasure brucellosis ...
Shivani eGoolab, Shivani eGoolab, Robyn Lindsay Roth, Henriette evan Heerden, Michael Craig Crampton   +4 more
doaj   +1 more source

Protective Effect of Lusianthridin on Hemin-Induced Low-Density Lipoprotein Oxidation [PDF]

, 2021
Su Wutyi Thant, Noppawan Phumala Morales, Visarut Buranasudja, Boonchoo Sritularak, Rataya Luechapudiporn   +4 more
openalex   +1 more source

Mettl3‐Mediated m6A Modification Represents a Novel Therapeutic Target for FSGS

Advanced Science, EarlyView.
This study explores the roles of Mettl3‐induced N6‐methyladenosine (m6A) modifications in Focal segmental glomerulosclerosis (FSGS). The findings reveal that inhibition of Mettl3 results in podocyte injury by modulating the TJP1CDC42 pathway. Moreover, Administration of N6‐methyladenosine attenuates the FSGS phenotype in WT mice induced by Adriamycin ...
Fubin Zhu, Hongzhi Li, Xiang Li, Chunxiu Du, Ting Wang, Xuling Zhou, Xiaobei Xie, Yunxia Shao, Yingzhi Huang, Yanling Hu, Xinxin Guo, Bin Zhu, Shanshan Yu, Xiaoyan Zhang, Binghai Zhao   +14 more
wiley   +1 more source

U-shaped association between low-density lipoprotein cholesterol levels and risk of all-cause mortality mediated by post-stroke infection in acute ischemic stroke

, 2023
Zimo Chen, Hongqiu Gu, Jinglin Mo, Kaixuan Yang, Yingyu Jiang, Xin Yang, Chunjuan Wang, Jie Xu, Xia Meng, Yong Jiang, Hao Li, Liping Liu, Yilong Wang, Xingquan Zhao, Zixiao Li, Yongjun Wang, Yong-Jun Wang, Yong-Jun Wang   +17 more
openalex   +1 more source

Vm–MSI: a Vancomycin–Antimicrobial Peptide Conjugate Combating Resistant Bacteria and Broadening the Antimicrobial Spectrum

Advanced Science, EarlyView.
A series of vancomycin‐antimicrobial peptide conjugates is synthesized and evaluated to identify the optimal combination. Vm‐MSI, selected from multiple candidates, exhibited potent activity against vancomycin‐resistant and Gram‐negative bacteria by disrupting membranes and inducing oxidative stress, thereby expanding vancomycin's antibacterial ...
Shuangyu Li, Kang Wang, Wenzhuang Shi, Xu Wang, Duxin Li, Yanli Liu, Peng Zhang, Yipeng Wang   +7 more
wiley   +1 more source

Antibodies to low-density lipoproteins modified by malonic dialdehyde: contents in blood and role in atherogenesis

Медицинская иммунология
In this work, we determined the content of antibodies to low-density lipoproteins modified by malondialdehyde, the concentration of circulating immune complexes cholesterol and oxidized low-density lipoproteins in the blood of healthy individuals and ...
A. A. Ivanova, A. A. Dmitrieva, A. D. Denisenko   +2 more
doaj   +1 more source