Results 131 to 140 of about 209,402 (307)

The heparan sulfate and its diverse biological activities

open access: yesCurrent Issues in Pharmacy and Medical Sciences, 2014
Heparan sulfate (HS) is one of the most common glycosaminoglycan (GAG) in mammals. It is composed of relatively simple disaccharide subunits, which, by further modification, such as sulfation and epimerization, potentially offer huge diversity in ...
Kaznowska-Bystryk Iwona
doaj   +1 more source

Optimization of the Isolation Method for Large‐Scale Production of Synthetic Bacterial Vesicles for Cancer Immunotherapy

open access: yesAdvanced Therapeutics, EarlyView.
This study introduces a reliable technique for the large‐scale production of bacterial vesicles that maintain their immune‐modulating potential, enabling industrial manufacturing and clinical applications. Although other cancer immunotherapies are available, this research presents an advanced bacterial vesicle‐based therapeutic option, with scalable ...
Negar Ordouzadeh   +6 more
wiley   +1 more source

Detection of vesicular lipoproteins in lecithin:cholesterol acyltransferase-deficient plasma by 1H-NMR spectroscopy.

open access: yesJournal of Lipid Research, 1989
The proton NMR spectra of the N-methyl choline region of normal and lecithin:cholesterol acyltransferase (LCAT)-deficient lipoproteins and of egg yolk phosphatidylcholine-cholesterol 55:45 (mol %) vesicle mixtures have been examined in the presence and ...
Y I Parmar   +4 more
doaj  

Rewiring Neuroimmunity: Nanoplatform Innovations for CNS Disease Therapy

open access: yesAdvanced Therapeutics, EarlyView.
This review explores emerging nanoplatform strategies designed to modulate neuroimmune responses for treating central nervous system (CNS) disorders. It examines structural and microenvironmental barriers, advances in multifunctional and targeted nanotechnologies, and highlights clinical progress and translational challenges, offering insights into the
Muhammad Usman Akbar   +7 more
wiley   +1 more source

Lipoprotein metabolism in the ovariectomized rat.

open access: yesJournal of Lipid Research, 1983
The hyperlipoproteinemia observed after ovariectomy in rats was previously shown to be associated with increased concentrations of cholesterol, triglycerides, and apolipoproteins B, E, and C.
B J van Lenten, G W Melchior, P S Roheim
doaj  

Development and Validation of Machine Learning‐Based Marker for Early Detection and Prognosis Stratification of Nonalcoholic Fatty Liver Disease

open access: yesAdvanced Science, EarlyView.
This study constructs a stacked multimodal machine learning model for nonalcoholic fattly liver disease (NAFLD) by integrating genetic and clinical features, and synthesize an in‐silico quantitative marker (ISNLD) that enables personalized risk stratification for intrahepatic and extrahepatic outcomes of high‐risk individuals of NAFLD.
Lushan Xiao   +14 more
wiley   +1 more source

Recognition of vesicular lipoproteins by the apolipoprotein B,E receptor of cultured fibroblasts.

open access: yesJournal of Lipid Research, 1988
Vesicular lipoproteins (e.g., lipoprotein-X) are found in plasma in cholestasis or following infusion of Intralipid or phospholipid. To investigate the metabolism of vesicular lipoproteins, we isolated them from the plasma of subjects with cholestasis or
K J Williams, A R Tall, I Tabas, C Blum
doaj  

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