Results 41 to 50 of about 23,180 (193)

Clinical Challenges in the Management of Leishmania/HIV Coinfection in a Nonendemic Area: A Case Report

open access: yesCase Reports in Infectious Diseases, 2012
We report on a 37-year-old male HIV-positive patient with generalized cutaneous leishmaniasis undiagnosed for several years. Upon presentation, visceral leishmaniasis was diagnosed in addition to cutaneous manifestation of the disease.
K. Grabmeier-Pfistershammer   +4 more
doaj   +1 more source

Clinically‐Relevant Static Magnetic Field Induces Release of Encapsulated Molecules from Magnetoliposomes

open access: yesSmall, EarlyView.
This work demonstrates the feasibility of a molecule release from magnetoliposomes triggered by a constant 1.5 T magnetic field currently used in clinical settings. ABSTRACT Magnetoliposomes (MLs) are known for their great potential in drug release under an alternating current (AC) magnetic field (MF).
Jules Mistral   +8 more
wiley   +1 more source

Experimental Models of Short Courses of Liposomal Amphotericin B for Induction Therapy for Cryptococcal Meningitis. [PDF]

open access: yes, 2017
Cryptococcal meningoencephalitis is a rapidly lethal infection in immunocompromised patients. Induction regimens are usually administered for 2-weeks. The shortest effective period of induction therapy with liposomal amphotericin B (LAmB) is unknown. The
Adam Johnson   +32 more
core   +1 more source

Leishmania donovani's protein tyrosine phosphatases interact with DUF21 and respond to environmental magnesium

open access: yesThe FEBS Journal, EarlyView.
The Leishmania phosphatase PTP1, and possibly the genetically similar PTP2, interacts with the Leishmania transmembrane protein DUF21. When both ptp1 and ptp2 are knocked out of Leishmania (LdΔPTP1/2), the parasite can no longer survive without magnesium in vitro and has reduced viability in the host macrophage. Conversely, in duf21 knockout (LdΔDUF21),
Kayla Paulini   +6 more
wiley   +1 more source

A difficult-to-treat pleuropulmonary histoplasmosis in a patient with rheumatoid arthritis in Taiwan

open access: yesJournal of Microbiology, Immunology and Infection, 2023
Amphotericin B and itraconazole are the primary agents for treating histoplasmosis. Newer azoles are alternatives for patients refractory to or intolerant of standard therapy.
Wen-Kai Chu   +6 more
doaj   +1 more source

Deep and disseminated dermatophytosis in immunocompromised populations—A systematic review

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
Dermatophyte infections of the dermis and subcutaneous tissue (i.e. deep dermatophytosis)—associated with secondary complications including pseudomycetoma and systemic dissemination—affect vulnerable populations with primary or acquired immunodeficiencies.
Aditya K. Gupta   +5 more
wiley   +1 more source

Population Pharmacokinetics of Liposomal Amphotericin B in Immunocompromised Children [PDF]

open access: yes, 2016
BACKGROUND Liposomal amphotericin B (LAmB) is widely used in the treatment of invasive fungal disease (IFD) in adults and children. There are relatively limited PK data to inform optimal dosing in children that achieves systemic drug exposures ...
Aljayyoussi, Ghaith   +9 more
core   +4 more sources

Successful treatment of breakthrough disseminated Trichosporon asahii fungemia in a patient with acute myeloid leukemia receiving itraconazole prophylaxis

open access: yesMedical Mycology Case Reports, 2018
We encountered a case of a 73-year-old man with acute myeloid leukemia who developed Trichosporon asahii systemic infection while on itraconazole prophylaxis during severe neutropenia. Cryptococcal antigen was useful for diagnosis.
Daiki Karigane   +6 more
doaj   +1 more source

PCR monitoring of response to liposomal amphotericin B treatment of systemic candidiasis in neutropenic mice [PDF]

open access: yes, 1996
When a diagnosis of invasive candidiasis has been made, treatment with toxic fungicidal agents is inevitable. The crucial decision of when to stop such treatment is difficult to make, because cultures are often negative despite ongoing ...
Belkum, A.F. (Alex) van   +5 more
core  

Molecular monitoring of minimal residual disease in two patients with MLL-rearranged acute myeloid leukemia and haploidentical transplantation after relapse [PDF]

open access: yes, 2012
This report describes the clinical courses of two acute myeloid leukemia patients. Both had MLL translocations, the first a t(10;11)(p11.2;q23) with MLL-AF10 and the second a t(11;19)(q23;p13.1) with MLL-ELL fusion.
Beyer, Jörg   +11 more
core   +1 more source

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