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Fatty acids negatively regulate platelet function through formation of noncanonical 15‐lipoxygenase‐derived eicosanoids [PDF]
Pharmacology Research & Perspectives, 2023 The antiplatelet effect of polyunsaturated fatty acids is primarily attributed to its metabolism to bioactive metabolites by oxygenases, such as lipoxygenases (LOX).
Adriana Yamaguchi +12 more
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Molecules, 2021 Soybean lipoxygenase was immobilized on nanoporous rice husk silica particles by adsorption, and enzymatic parameters of the immobilized protein, including the efficiency of substrate binding and catalysis, kinetic and operational stability, and the ...
Putheary Ngin, Kyoungwon Cho, Oksoo Han
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Lipoxygenase in Wheat: Genetic Control and Impact on Stability of Lutein and Lutein Esters
Foods, 2021 Preservation of lutein concentrations in wheat-based end-products during processing is important both for product quality and nutritional value. A key constituent involved in lutein degradation is endogenous lipoxygenase.
Daryl J. Mares +3 more
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Regulated Spatial Distribution of Cyclooxygenases and Lipoxygenases in Crohn's Ulcer
Mediators of Inflammation, 2006 Background and Aims. Arachidonic acid metabolism actively participates in the initiation, climaxing, and resolution phases of inflammation, and its close connection with inflammatory bowel diseases has been only recently discovered.
Yao Mao, Jian'an Ren, Jieshou Li
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Lipoxygenase Inhibition by Plant Extracts
Biomolecules, 2021 Lipoxygenases are widespread enzymes that catalyze oxidation of polyunsaturated fatty acids (linoleic, linolenic, and arachidonic acid) to produce hydroperoxides.
Melita Lončarić +5 more
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Lipoxygenase mRNA in cultured human epidermal and oral keratinocytes
Journal of Lipid Research, 1995 Although 15-lipoxygenase has not been purified from cultured human keratinocytes nor has cDNA coding for the protein been isolated from this source, this enzyme activity is implied by the finding of its stereospecific product in in vitro experiments ...
H Zhao +3 more
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Lipoxygenase in the plant kingdom. II. Physiological functions proposed
Grasas y Aceites, 1992 In spite of the large number of publications about lipoxygenase, little definitive information is available concerning physiological roles for plant lipoxygenase.
L. C. Sánchez +2 more
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Journal of Lipid Research, 2021 A proposed beneficial impact of highly unsaturated “fish oil” fatty acids is their conversion by lipoxygenase (LOX) enzymes to specialized proresolving lipid mediators, including 12/15-LOX products from EPA and DHA.
Jing Jin +2 more
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Oxidative modification of human lipoproteins by lipoxygenases of different positional specificities
Journal of Lipid Research, 1994 Cellular lipoxygenases have been implicated in foam cell formation during the early stages of atherogenesis. We studied the interaction of lipoxygenases of different positional specificities with human lipoproteins and found that the arachidonate 15 ...
H Kühn, J Belkner, H Suzuki, S Yamamoto
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Frontiers in Plant Science, 2022 Lipoxygenases (LOXs) are a gene family of nonheme iron-containing dioxygenases that play important roles in plant development and defense responses. To date, a comprehensive analysis of LOX genes and their biological functions in response to abiotic ...
Yifei Mou +7 more
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