Integrated Immune, Epithelial and Lipid Pathways in NSAID‐Exacerbated Respiratory Disease
ABSTRACT NSAID‐exacerbated respiratory disease (N‐ERD) is a chronic inflammatory disorder characterized by asthma, chronic rhinosinusitis with nasal polyps and respiratory reactions to cyclooxygenase‐1 inhibiting nonsteroidal anti‐inflammatory drugs (NSAID).
Piotr Szatkowski, Lucyna Mastalerz
wiley +1 more source
Neutrophil‐based immunotherapy: A metabolic lens on mechanisms and therapeutic implications
TAN metabolic reprogramming critically contributes to tumour immune evasion. A 4‑Tier TAN‑MetaC classification framework is proposed, along with an overview of translational opportunities and bottlenecks for TAN metabolism‑targeted immunotherapies. Abstract Background Tumor‐associated neutrophils (TANs) serve as pivotal immune modulators in the tumor ...
Wenchao Xu +4 more
wiley +1 more source
Activation and execution of lipoxygenase catalysis. [PDF]
Brash AR, Oliw EH.
europepmc +1 more source
Insights Into the Biological Mechanisms and Multifunctional Health Benefits of Morelloflavone
Morelloflavone (MF), a biflavonoid from Garcinia and related species, exhibits broad human health benefits through antioxidant, anti‐inflammatory, anticancer, and metabolic regulatory effects. This review highlights its molecular mechanisms, biosynthesis, and emerging roles in chronic disease prevention, emphasizing systems biology and machine learning
Yi Liu +4 more
wiley +1 more source
Plasma Linoleic Acid Is Associated With Pediatric Sepsis Phenotype and Acute Kidney Injury. [PDF]
Saraiva IE +13 more
europepmc +1 more source
Overview of MSG‐assisted GABA enrichment and associated changes in amino acid, fatty acid, and volatile metabolite profiles in germinated black highland barley. ABSTRACT γ‐Aminobutyric acid (GABA) is a functional amino acid with multiple health benefits; however, the mechanism of its enrichment in black highland barley, particularly through precursor ...
Xiaohang Lu, Nana Ma, Yuan Wang
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In vitro adventitious root culture of Withania somnifera L.: a strategy for enhanced secondary metabolite production with therapeutic antioxidant and anti-inflammatory potential. [PDF]
Mohammed DM +5 more
europepmc +1 more source
Calamus guruba Buch.‐Ham. (family Arecaceae) is a highly regarded traditional medicinal plant known for its diverse therapeutic benefits. This research aimed to investigate the antidiabetic, anti‐inflammatory, anxiolytic, and antidepressant effects of the methanolic extract of C. guruba (MECG).
Mohi Uddin +5 more
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Coumarin-Amino Acid Hybrids Used as Possible Multifactorial Anti-Inflammatory Agents. [PDF]
Fotopoulos I, Hadjipavlou-Litina D.
europepmc +1 more source
Development and Characterization of Low‐Glycemic Couscous Enriched With β‐Glucans and Proteins
Traditional couscous production with 50/50 blends of different raw materials (wheat, barley and lentil). ABSTRACT In this study, a novel functional couscous with reduced glycemic potential was developed by enrichment of traditional couscous with β‐glucan and protein through the addition of hull‐less barley (cv. Chifaa) and lentil flours.
Ece Surek +10 more
wiley +1 more source

