Results 151 to 160 of about 50,780 (245)

Chemical Profiling, Analgesic and Anti-Inflammatory Activities of <i>Farsetia aegyptia</i> and <i>Zilla spinosa</i>: Integrated In Vitro, In Vivo, and In Silico Studies. [PDF]

Plants (Basel)
Besbes M, Hamdi A, Majouli K, Horchani M, Alshammari AA, Jilani S, Lotfi SA, Hadj Lajimi R, Jannet HB, Ben Selma W, Kraiem J.   +10 more
europepmc   +1 more source

The Relationship Between (Endo)cannabinoids, the Microbiome and Melanoma

Pharmacology Research &Perspectives, Volume 14, Issue 4, August 2026.
CB1 and CB2 receptors are widely distributed in both normal and cancerous cells. Cannabinoids have a positive impact on reducing tumor growth in mice. A positive relationship exists between CB2 receptors and survival in skin melanoma. However, there is a negative impact on non‐small cell lung cancer and colon cancer, whereas a higher association of CB1
Farideh A. Javid, Marin Golčić, Anja Harej Hrkać, Andrej Belančić   +3 more
wiley   +1 more source

Gut Microbiota Modulate Adipose Eicosanoid Metabolism: Potential Roles of the Lipoxygenase Pathway. [PDF]

FASEB J
Wang Y, Edin ML, Jing N, Lih FB, Yang J, Yeliseyev V, Zeldin DC, Zhang G.   +7 more
europepmc   +1 more source

Isothiocyanates as Ferroptosis Inducers to Promote Cancer Cell Death

Phytotherapy Research, Volume 40, Issue 8, Page 5119-5131, August 2026.
ABSTRACT Cancer remains a leading cause of global mortality, with the therapeutic efficacy of anticancer drugs often hampered by late diagnosis and the development of chemotherapy resistance. Ferroptosis is an iron‐dependent form of regulated non‐apoptotic cell death driven by lipid peroxidation.
Valentina Citi, Renda Chahna, Francesca Maffei, Alma Martelli, Vincenzo Calderone, Carmela Fimognari, Eleonora Turrini   +6 more
wiley   +1 more source

Allosteric properties of mammalian ALOX15 orthologs. [PDF]

J Biol Chem
Yang J, Borchert A, Kuhn H.
europepmc   +1 more source

Artificial exposure to herbivore‐induced volatile organic compounds reduces herbivory and modulates gene expression in potato plants

Journal of Applied Ecology, Volume 63, Issue 8, August 2026.
These findings provide strong mechanistic evidence for VOCs mediating pest resistance and suggest that exposure to herbivore‐induced, plant‐derived VOCs can enhance pest resistance in potato crops. These results might offer novel information for developing ecologically sustainable plant volatile‐based strategies for boosting protection against pests in
Lucía Martín‐Cacheda, Alessio Tei, Gregory Röder, Yolanda Arnaiz, Luis Abdala‐Roberts, Xoaquín Moreira   +5 more
wiley   +1 more source

Optimizing Wheat Milling By-Products: An Overview of Processing Techniques. [PDF]

Foods
Khashaba RA, Lou H, Li Y, Saeed Omer SH, Wang X, Gu Z, Zhao R.   +6 more
europepmc   +1 more source

South African Herbal Teas and Diabetes‐Mediated Mitochondrial Dysfunction: Emerging Evidence and Mechanistic Insights

Journal of Food Science, Volume 91, Issue 8, August 2026.
ABSTRACT Type 2 diabetes mellitus (T2DM) is a central component of the metabolic syndrome (MetS) and is associated with underlying mitochondrial dysfunction. Disruption of mitochondrial homeostasis impairs cellular energy metabolism and contributes to the overproduction of reactive oxygen species (ROS), leading to oxidative stress, chronic inflammation,
Shanika Reddy, Naeem Sheik Abdul, Taskeen Fathima Docrat, Jeanine Marnewick   +3 more
wiley   +1 more source

A Lipoxygenase 3 mutation reverses growth phenotypes in an Arabidopsis Plastid Lipase 3 overexpression line. [PDF]

PLoS One
Mugume Y, Cook R, Hagerty B, Liu J, Alvord ZB, Danhof L, Froehlich JE, Vermaas JV, Benning C.   +8 more
europepmc   +1 more source

Opposing roles of DGAT‐mediated lipid droplet biogenesis in the regulation of ferroptosis sensitivity

The FEBS Journal, Volume 293, Issue 15, Page 4508-4532, August 2026.
Ferroptosis is driven by unrestricted peroxidation of polyunsaturated fatty acyl (PUFA) chains in membrane phospholipids. In triple‐negative breast cancer cells, lipid droplets (LDs) sequester dietary PUFAs, limiting their incorporation into membrane phospholipids, preventing mitochondrial damage, and reducing lipid peroxidation and ferroptosis.
Ana Kump, Leja Perne, Špela Koren, Eva Jarc Jovičić, Nastja Feguš, Carina Pinto Kozmus, Michele Wölk, Kristyna Brejchova, Maria Fedorova, Ondrej Kuda, Toni Petan   +10 more
wiley   +1 more source