ABSTRACT Background and Aims Atherosclerosis is a lipid‐induced chronic inflammatory cardiovascular disorder denoted by the infiltration of immune cells and the agglomeration of lipids in the intima, the innermost layer, of the arteries of large and medium sizes.
Ramin Lotfi +4 more
wiley +1 more source
Integrated Multi-Omics Analysis Reveals Lipid Metabolism-Mediated Preservation of Postharvest Broccoli Yellowing by Static Magnetic Field. [PDF]
Lu YB +4 more
europepmc +1 more source
ATF4/SCO2 Inhibits Ferroptosis in Lung Cancer Through Activating the MAPK Signaling Pathway
ATF4 activates the transcription of SCO2 to increase SCO2 expression that further stimulates p38/ERK1 signals in MAPK pathway, ultimately promoting proliferation and migration while inhibiting apoptosis and ferroptosis of lung cancer cells. ABSTRACT Ferroptosis is a specific cell death form resulting from the iron‐dependent lipid peroxidation ...
Liang Yu +6 more
wiley +1 more source
Overexpression and knockdown of 5-lipoxygenase regulates the migration and invasion of colorectal cancer cells. [PDF]
Li X +7 more
europepmc +1 more source
ABSTRACT Background Skeletal muscle atrophy in amyotrophic lateral sclerosis (ALS) drives loss of muscle strength, function and quality of life in ALS patients. The endocannabinoid system (ECS) regulates muscle homeostasis via regenerative and metabolic processes, and although ECS alterations have been reported in ALS neural tissues, ECS remodelling ...
Sebastiaan Dalle +7 more
wiley +1 more source
Computational Method for the Detection of Communication Pathways in Enzymes that Correlate with Experimentally Defined Thermal Activation Networks. [PDF]
Jiang Y, Cordova JP, Klinman JP.
europepmc +1 more source
Inflammation in cardiovascular disease is a dynamic and context‐dependent network rather than a secondary response to injury. Mitochondrial danger signaling links metabolic stress to immune activation through TLR priming, NLRP3 inflammasome amplification, cGAS–STING signaling, and immunometabolic gating, providing a basis for more precise therapeutic ...
Jiaxiang Rong +8 more
wiley +1 more source
RETRACTION: The 12-15-Lipoxygenase is a Modulator of Alzheimer's-Related Tau Pathology In Vivo. [PDF]
europepmc +1 more source
<i>Brassica nigra</i> L. Seed Extracts as a Promising Source of Antioxidant and Anti-Inflammatory Agents. [PDF]
Nitthikan N +4 more
europepmc +1 more source
Lymphatic Endothelial Cells in Health and Disease
Lymphatic endothelial cells (LECs) are dynamic regulators of tissue homeostasis and disease remodeling. In the healthy state, LECs coordinate interstitial fluid drainage, intestinal lipid transport, and immune trafficking and tolerance. Across disease settings, however, these same programs become maladaptively reprogrammed, contributing to barrier ...
Du Tang +5 more
wiley +1 more source

