Results 141 to 150 of about 50,780 (245)

The Role of Immunoresolvents in Atherosclerosis: A Mini‐Review on Their Biology and Therapeutic Opportunities

open access: yesHealth Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Atherosclerosis is a lipid‐induced chronic inflammatory cardiovascular disorder denoted by the infiltration of immune cells and the agglomeration of lipids in the intima, the innermost layer, of the arteries of large and medium sizes.
Ramin Lotfi   +4 more
wiley   +1 more source

ATF4/SCO2 Inhibits Ferroptosis in Lung Cancer Through Activating the MAPK Signaling Pathway

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
ATF4 activates the transcription of SCO2 to increase SCO2 expression that further stimulates p38/ERK1 signals in MAPK pathway, ultimately promoting proliferation and migration while inhibiting apoptosis and ferroptosis of lung cancer cells. ABSTRACT Ferroptosis is a specific cell death form resulting from the iron‐dependent lipid peroxidation ...
Liang Yu   +6 more
wiley   +1 more source

Early and Divergent Lipid Mediator Remodelling in Fast Versus Slow Skeletal Muscles of Female hSOD1G93A Mice

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 4, August 2026.
ABSTRACT Background Skeletal muscle atrophy in amyotrophic lateral sclerosis (ALS) drives loss of muscle strength, function and quality of life in ALS patients. The endocannabinoid system (ECS) regulates muscle homeostasis via regenerative and metabolic processes, and although ECS alterations have been reported in ALS neural tissues, ECS remodelling ...
Sebastiaan Dalle   +7 more
wiley   +1 more source

The Role of Inflammation and Immunity in Cardiovascular Disease: Molecular Mechanisms and Therapeutic Targets

open access: yesMedComm, Volume 7, Issue 8, August 2026.
Inflammation in cardiovascular disease is a dynamic and context‐dependent network rather than a secondary response to injury. Mitochondrial danger signaling links metabolic stress to immune activation through TLR priming, NLRP3 inflammasome amplification, cGAS–STING signaling, and immunometabolic gating, providing a basis for more precise therapeutic ...
Jiaxiang Rong   +8 more
wiley   +1 more source

Lymphatic Endothelial Cells in Health and Disease

open access: yesMedComm, Volume 7, Issue 8, August 2026.
Lymphatic endothelial cells (LECs) are dynamic regulators of tissue homeostasis and disease remodeling. In the healthy state, LECs coordinate interstitial fluid drainage, intestinal lipid transport, and immune trafficking and tolerance. Across disease settings, however, these same programs become maladaptively reprogrammed, contributing to barrier ...
Du Tang   +5 more
wiley   +1 more source

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