Results 191 to 200 of about 100,547 (310)

Differential regulation of 5-lipoxygenase and leukotriene-C4-synthase expression by IFNγ, IL-4 and IL-13 in human monocytes and macrophages from patients with atopic dermatitis. [PDF]

Inflamm Res
Lietzau S, Traidl S, Riesselmann C, Werfel T, Mommert S.   +4 more
europepmc   +1 more source

Lipoxygenase

Journal of Japan Oil Chemists' Society, 1965
openaire   +2 more sources

Lipoxygenases

, 1982
Vliegenthart, J.F.G., Veldink, G.A.
openaire   +2 more sources

The biosynthesis of isoprenoid compounds in the chloroplast from the compartmental view [PDF]

, 1982
Fiedler, Erich, Schultz, Gernot, Soll, Jürgen, Wintermanns, F. G. J. M.   +3 more
core  

Liver‐Specific Suppression of PLA2G6/iPLA2β Improves Glucose and Lipid Metabolism in High‐Fat Diet‐Fed Mice

The FASEB Journal, Volume 40, Issue 8, 30 April 2026.
Liver‐specific suppression of PLA2G6/iPLA2β by utilizing the short‐hairpin RNA knockdown technique using an adenovirus vector (Ad‐shPLA2G6) altered phospholipid and fatty acid metabolites and suppressed hepatic lipid accumulation, serum triglyceride, and fasting glucose levels.
Kahori Shimizu, Mana Nishibata, Katsuyuki Nagata, Sho Hori, Shotaro Michinaga, Miyuki Kanehara, Miho Hashimoto‐Iwasaki, Fuminori Sakurai, Hideo Shindou, Koji Tomita, Toru Nishinaka, Hiroyuki Mizuguchi   +11 more
wiley   +1 more source

Radioiodination of Two Carborane‐Based Dual Cyclooxygenase‐2/5‐Lipoxygenase Inhibitors and Their In Vitro and In Vivo Evaluation

ChemBioChem, Volume 27, Issue 7, 14 April 2026.
Two dicarbadodecaborane(12)‐based dual cyclooxygenase‐2/5‐lipoxygenase (COX‐2/5‐LO) inhibitors were 123I‐labeled. Refinement of labeling and formulation conditions and extensive in vitro characterization are presented. Cell uptake studies in COX‐2‐ and 5‐LO‐overexpressing cell lines showed COX‐2‐independent and partly 5‐LO‐dependent uptake.
Jonas Schädlich, Martin Ullrich, Cathleen Haase‐Kohn, Robert Wodtke, Sebastian Braun, Maximilian Molitor, Bettina Hofmann, Dieter Steinhilber, Klaus Kopka, Evamarie Hey‐Hawkins, Jens Pietzsch, Markus Laube   +11 more
wiley   +1 more source

Isolation and Biophysical Characterization of Lipoxygenase-1 from Soybean Seed, a Versatile Biocatalyst for Industrial Applications. [PDF]

Biomolecules
Gerogianni I, Vardaxi A, Matis I, Karayianni M, Zoumpanioti M, Mavromoustakos T, Pispas S, Chrysina ED.   +7 more
europepmc   +1 more source

Monocyte LOXHD1 and RHOB Expression Predictive of Progressive Systemic Sclerosis–Associated Interstitial Lung Disease

Arthritis Care &Research, Volume 78, Issue 4, Page 456-468, April 2026.
Objective A leading cause of death among patients with scleroderma (SSc), interstitial lung disease (ILD) remains challenging to prognosticate. The discovery of biomarkers that accurately determine which patients would benefit from close monitoring and aggressive therapy would be an essential clinical tool.
Cristina M. Padilla, Robert Lafyatis, Kevin F. Gibson, Christina Morse, Eleanor Valenzi, Xiaoping Chen, Xiaoyun Li, Yanwu Zhao, Yongseok Park, Dana Ascherman, Jonathan Minden, Robyn Domsic, Yingze Zhang, Daniel J. Kass   +13 more
wiley   +1 more source

Resolving Inflammation in CKD: The Potential of SPMs and Omega-3 Derivatives as Biomarkers and Therapeutics. [PDF]

Biomedicines
Franczyk B, Lisińska W, Hossa K, Katańska K, Wieczorek A, Prusak A, Biegała Z, Rysz J, Młynarska E.   +8 more
europepmc   +1 more source

Resolvin D5 Inhibits CXCL8 Expression in Colonic Epithelial Cells Through Activating GPR101 to Impede Neutrophil Recruitment and Consequently Alleviate Ulcerative Colitis

Advanced Science, Volume 13, Issue 21, 13 April 2026.
RvD5 effectively alleviates UC by inhibiting STAT1 signaling to reduce CXCL8 expression in colonic epithelial cells via activation of GPR101, which subsequently decreases the infiltration of neutrophils in the colonic mucosal epithelium. Epimedin A1, a natural allosteric inhibitor of 5‐LOX, demonstrates potential as a therapeutic agent for UC by ...
Pengxiang Guo, Yilei Guo, Yanrong Zhu, Ke Yan, Yulai Fang, Jiafeng Zhang, Yue He, Zhifeng Wei, Yufeng Xia, Yue Dai   +9 more
wiley   +1 more source