The Emerging Parkinson's Disease Oxylipin‐Ome
ABSTRACT Parkinson Disease (PD) is increasingly considered a proteinopathy and lipidopathy. This proteinopathy+lipidopathy paradigm has been further refined to a fatty acid (FA)‐opathy, centering dysregulated FA metabolism as fundamental in PD lipid dysfunction.
Julia C. Kelliher, Saranna Fanning
wiley +1 more source
ABSTRACT Lipids are important for metabolic processes, mainly cytokine regulation in the skeletal muscle and liver. Considering the soybean oil concentration, a weighted gene co‐expression network analysis (WGCNA) was used to perform an integrative analysis in skeletal muscle and liver tissues.
Fernanda Nery Ciconello +9 more
wiley +1 more source
Allosteric properties of mammalian ALOX15 orthologs. [PDF]
Yang J, Borchert A, Kuhn H.
europepmc +1 more source
15-lipoxygenase- I in atherosclerosis, angiogenesis and tumorigenesis studies with retro- and adenovirus mediated gene transfer techniques [PDF]
Viita, Helena
core
Algerian royal jelly from native honey bees shows chemical diversity influenced by geography and subspecies. Lyophilization preserves key compounds, including 10‐HDA and phenolics. Biological assays reveal modest antioxidant activity and selective cytotoxicity against Reh leukemia cells, while anti‐inflammatory effects are limited.
A. S. Ayad +7 more
wiley +1 more source
Optimizing Wheat Milling By-Products: An Overview of Processing Techniques. [PDF]
Khashaba RA +6 more
europepmc +1 more source
A Lipoxygenase 3 mutation reverses growth phenotypes in an Arabidopsis Plastid Lipase 3 overexpression line. [PDF]
Mugume Y +8 more
europepmc +1 more source
Post‐stroke administration of TSN significantly reduced infarct volume, neuroinflammation, and improved functional recovery of MCAO mice. TSN alleviated neural oxidative stress, lipid peroxidation, and ferroptosis in MCAO mice. TSN modulated the infiltration of immune cells in MCAO mice in vivo and T cell differentiation in vitro.
Xinyun Li +5 more
wiley +1 more source
Interaction between microorganisms and flavour products during cigar fermentation promoted by citrus Reticulata-"Chenpi" derived <i>Enterobacter</i> G5Z-2: based on multi-omics studies and microbial profiles. [PDF]
Zhang J +8 more
europepmc +1 more source
Mechanisms of Gui Zhi Fu Ling Formula in Liver Fibrosis: Metabolomics and Gut Microbiota Analysis
Our study was based on the efficacy of the phenotype in an animal model and used multi‐omics to explore the mechanism of action of the compound. We found that Gui Zhi Fu Ling Formula may ameliorate hepatic fibrosis potentially associated with increased hepatic EPA and the expression of gut Pseudomonas.
Xiaoliang Deng +5 more
wiley +1 more source

