Results 121 to 130 of about 23,162 (241)

Systemic acquired resistance: an emerging role for jasmonates in local signal biogenesis, translocation and distal signal decoding

New Phytologist, Volume 251, Issue 6, Page 3142-3158, September 2026.
Jasmonate signalling underpins establishment of plant systemic acquired resistance (SAR). Activation of the hypersensitive response (HR) not only contains the pathogen but establishes broad spectrum resistance in unchallenged leaves. The strong burst of reactive oxygen/nitrogen species initiating the HR results in lipid peroxidation (illustrated by ...
Fay Bennett, Erin Stroud, Pradeep Kachroo, Murray Grant   +3 more
wiley   +1 more source

New Hydroxycinnamic Acid Esters as Novel 5-Lipoxygenase Inhibitors That Affect Leukotriene Biosynthesis. [PDF]

Mediators Inflamm, 2017
Boudreau LH, Boudreau LH, Lassalle-Claux G, Cormier M, Blanchard S, Doucet MS, Surette ME, Touaibia M.   +7 more
europepmc   +1 more source

Integrated Multi‐Omic Analyses Uncover a Regulatory Link Between Photosynthesis and Drought Tolerance in Field‐Grown Sorghum

Plant, Cell &Environment, Volume 49, Issue 9, Page 6748-6764, September 2026.
ABSTRACT Global warming and increasing water scarcity pose major challenges to agriculture, emphasising the need to translate stress‐biology insights into the development of drought‐resilient cultivars. In this study, we evaluated a panel of six diverse sorghum (Sorghum bicolour) accessions grown under field‐imposed drought conditions in central ...
Li'ang Yu, Giovanni Melandri, Anna C. Nelson Dittrich, Hamada AbdElgawad, Gerrit T. S. Beemster, Ciara Garcia, A. Elizabeth Arnold, Brian D. Gregory, Duke Pauli, Andrew D. L. Nelson   +9 more
wiley   +1 more source

Ferroptosis‐Based Peripheral Immune Dysregulation and Diagnostic Signatures in Parkinson's Disease: An RNA Transcriptomic and Single‐Cell Immune Sequencing Analysis

The FASEB Journal, Volume 40, Issue 15, 15 August 2026.
This study explored the crosstalk between ferroptosis‐related genes and peripheral immune alterations in Parkinson's disease. We constructed a gene signature and classified molecular subtypes, and further pinpointed key ferroptosis‐associated molecules in immune cells and neuronal cells.
Lei Cheng, Jing Zhang, Wen‐Ting Shi, Qing Ye, Chen Huang, Zhong‐Yan Zhou   +5 more
wiley   +1 more source

5-LIPOXYGENASE INHIBITORS [PDF]

, 2011
VERMA ASHWANI KUMAR, MALHOTRA SANJAY, MARIMGANTI SRINIVASA, BHATNAGAR PRADIP KUMAR, CLIFFE IAN A, RAY ABHIJIT, GUPTA SUMAN, SRIVASTAVA PUNIT, DASTIDAR SUNANDA GHOSH   +8 more
  +6 more sources

Sulfated Cyclocarya Paliurus Polysaccharide Sorchestrates the Gut Microbiome to Mobilize a Host‐Derived 12‐HEPE Against Ulcerative Colitis

Advanced Science, Volume 13, Issue 44, 7 August 2026.
A sulfated polysaccharide (SCP) from Cyclocarya paliurus alleviates ulcerative colitis by reshaping the gut microbiome. This remodeled microbiota orchestrates the upregulation of the host‐derived lipid 12‐HEPE, which directly inhibits the TLR4/NF‐κB pathway to suppress inflammation.
Xianxiang Chen, Mingyue Shen, Rui Zhang, Zhibing Huang, Hui Niu, Qiang Yu, Yi Chen, Xiangwen Pan, Liyuan Rong, Huiliang Wen, Jun Yang, Jianhua Xie   +11 more
wiley   +1 more source

Quantum Phenomena in Molecular and Biological Systems: A Decoherence‐Based Decision Framework With Falsifiable Predictions and a Failure‐Mode Taxonomy

Advanced Physics Research, Volume 5, Issue 8, August 2026.
A physics‐grounded framework based on decoherence timescales (τ_dec vs τ_func), Markovian validity, and falsifiability criteria is applied across molecular systems to distinguish where quantum effects are necessary, marginal, or irrelevant. The analysis integrates quantum chemistry, biological quantum mechanisms, and quantum computing under a unified ...
Sarfaraz K. Niazi
wiley   +1 more source

Overcoming Radiation Resistance: Ferroptosis Induction to Sensitize Solid Tumors to Radiation Therapy

Cancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT Radiation therapy (RT) is a mainstay of treatment for a myriad of cancers, often utilized for tumors that are unable to be resected, as well as an adjunct to surgery and chemotherapy. Unfortunately, many cancers are resistant to RT‐induced damage and subsequent cell death.
Joseph Carmicheal, Caden M. Fritson, Alexandra Seas, Heidi Vieira, Surinder K. Batra   +4 more
wiley   +1 more source

A high-throughput mass spectrometric assay for discovery of human lipoxygenase inhibitors and allosteric effectors. [PDF]

Anal Biochem, 2015
Jameson JB, Kenyon V, Holman TR.
europepmc   +1 more source

Phytochemical Profiling and Biological Evaluation of Anthyllis henoniana Organs: Integrated In Vitro and Molecular Docking Insights Into Antioxidant, Anti‐Inflammatory, and Cytotoxic Potential

Chemistry &Biodiversity, Volume 23, Issue 8, August 2026.
Anthyllis henoniana aerial parts were subjected to fractionated extraction. Methanolic fractions yielded high total phenolic and flavonoid contents with strong antiradical (anti‐DPPH) and neuroprotective (anti‐AChE) activities, whereas dichloromethane and cyclohexane fractions demonstrated potent cytotoxicity (anti‐MCF‐7, anti‐HCT‐116) and anti ...
Sabrine Jaber, Rami Rahmani, Jalloul Bouajila, Mohamed Debouba   +3 more
wiley   +1 more source