Results 131 to 140 of about 25,002 (268)
Design, synthesis, and SAR study of isopropoxy allylbenzene derivatives as 15-lipoxygenase inhibitors. [PDF]
Iran J Basic Med Sci, 2020 Mousavian M +5 more
europepmc +1 more source
Role of Cysteinyl Leukotrienes in Food Allergy and Anaphylaxis: A Potential Therapeutic Target
Allergy, EarlyView.
A. Weingaertner, T. Eiwegger
wiley +1 more source
Periodontitis as a Model for Inflammatory Uncoupling of Bone Remodeling
Journal of Periodontal Research, EarlyView.Periodontitis can be viewed as a state of inflammatory uncoupling of bone remodeling, in which excessive osteoclast‐mediated resorption coexists with impaired bone formation. This review integrates emerging insights from osteoimmunology, osteocyte biology, mechanobiology, aging, and resolution pathways to position periodontitis as an accessible in vivo
Rafael Scaf de Molon +4 more
wiley +1 more source
Journal of Veterinary Pharmacology and Therapeutics, EarlyView.ABSTRACT Cyclooxygenases (COX‐1 and COX‐2) are key enzymes in the biosynthesis of prostanoids, which mediate physiological functions, inflammation, and the process of carcinogenesis. In dogs and cats, lower urinary tract diseases are prevalent and often complex, requiring targeted therapeutic interventions.
Reiner Silveira de Moraes +8 more
wiley +1 more source
New Phytologist, EarlyView.Jasmonate signalling underpins establishment of plant systemic acquired resistance (SAR). Activation of the hypersensitive response (HR) not only contains the pathogen but establishes broad spectrum resistance in unchallenged leaves. The strong burst of reactive oxygen/nitrogen species initiating the HR results in lipid peroxidation (illustrated by ...
Fay Bennett +3 more
wiley +1 more source
A Novel AP2/ERF Transcription Factor Controls Trichome Initiation and Fruit Development in Cucumber
Plant Biotechnology Journal, EarlyView.ABSTRACT Trichomes, the hair‐like outgrowths of the plant epidermis, are critical for defence, reproduction and development. However, the underlying molecular mechanisms governing their initiation remain elusive. Here, we identified CsGL2, an AP2/ERF transcription factor, as a key integrator controlling trichome initiation and fruit development in ...
Haifan Wen +8 more
wiley +1 more source
Synthesis and structure-activity relationships of novel 5-(hydroxamic acid)methyl oxazolidinone derivatives as 5-lipoxygenase inhibitors. [PDF]
J Enzyme Inhib Med Chem, 2020 Phillips OA, Bosso MA, Ezeamuzie CI.
europepmc +1 more source
Plant Biotechnology Journal, EarlyView.ABSTRACT Rice is the staple crop for more than half of the global population, and improving grain yield, grain quality, and stress resistance remain central goals of modern rice breeding. Among current precision breeding strategies, genome editing has created new opportunities for crop improvement, but its success depends heavily on the selection of ...
Wenhao Wu +4 more
wiley +1 more source
Plant, Cell &Environment, EarlyView.ABSTRACT Global warming and increasing water scarcity pose major challenges to agriculture, emphasising the need to translate stress‐biology insights into the development of drought‐resilient cultivars. In this study, we evaluated a panel of six diverse sorghum (Sorghum bicolour) accessions grown under field‐imposed drought conditions in central ...
Li'ang Yu +9 more
wiley +1 more source
Lipoxygenase Inhibitors Shift the Yeast/Mycelium Dimorphism in \u3ci\u3eCeratocystis ulmi\u3c/i\u3e [PDF]
, 1992 The yeast-mycelium dimorphism in Ceratocystis ulmi, the causative agent of Dutch elm disease, was switched by gossypol, nordihydroguaiaretic acid, and propylgallate. In each case the mycelial form was converted to the yeast form.
Jensen, Ellen C. +2 more
core +1 more source