Results 131 to 140 of about 23,162 (241)
Integrated Immune, Epithelial and Lipid Pathways in NSAID‐Exacerbated Respiratory Disease
ABSTRACT NSAID‐exacerbated respiratory disease (N‐ERD) is a chronic inflammatory disorder characterized by asthma, chronic rhinosinusitis with nasal polyps and respiratory reactions to cyclooxygenase‐1 inhibiting nonsteroidal anti‐inflammatory drugs (NSAID).
Piotr Szatkowski, Lucyna Mastalerz
wiley +1 more source
Neutrophil‐based immunotherapy: A metabolic lens on mechanisms and therapeutic implications
TAN metabolic reprogramming critically contributes to tumour immune evasion. A 4‑Tier TAN‑MetaC classification framework is proposed, along with an overview of translational opportunities and bottlenecks for TAN metabolism‑targeted immunotherapies. Abstract Background Tumor‐associated neutrophils (TANs) serve as pivotal immune modulators in the tumor ...
Wenchao Xu +4 more
wiley +1 more source
The potential of 12/15-lipoxygenase inhibitors in stroke therapy. [PDF]
van Leyen K, Holman TR, Maloney DJ.
europepmc +1 more source
Insights Into the Biological Mechanisms and Multifunctional Health Benefits of Morelloflavone
Morelloflavone (MF), a biflavonoid from Garcinia and related species, exhibits broad human health benefits through antioxidant, anti‐inflammatory, anticancer, and metabolic regulatory effects. This review highlights its molecular mechanisms, biosynthesis, and emerging roles in chronic disease prevention, emphasizing systems biology and machine learning
Yi Liu +4 more
wiley +1 more source
Overview of MSG‐assisted GABA enrichment and associated changes in amino acid, fatty acid, and volatile metabolite profiles in germinated black highland barley. ABSTRACT γ‐Aminobutyric acid (GABA) is a functional amino acid with multiple health benefits; however, the mechanism of its enrichment in black highland barley, particularly through precursor ...
Xiaohang Lu, Nana Ma, Yuan Wang
wiley +1 more source
Calamus guruba Buch.‐Ham. (family Arecaceae) is a highly regarded traditional medicinal plant known for its diverse therapeutic benefits. This research aimed to investigate the antidiabetic, anti‐inflammatory, anxiolytic, and antidepressant effects of the methanolic extract of C. guruba (MECG).
Mohi Uddin +5 more
wiley +1 more source
Development and Characterization of Low‐Glycemic Couscous Enriched With β‐Glucans and Proteins
Traditional couscous production with 50/50 blends of different raw materials (wheat, barley and lentil). ABSTRACT In this study, a novel functional couscous with reduced glycemic potential was developed by enrichment of traditional couscous with β‐glucan and protein through the addition of hull‐less barley (cv. Chifaa) and lentil flours.
Ece Surek +10 more
wiley +1 more source
ABSTRACT Background and Aims Atherosclerosis is a lipid‐induced chronic inflammatory cardiovascular disorder denoted by the infiltration of immune cells and the agglomeration of lipids in the intima, the innermost layer, of the arteries of large and medium sizes.
Ramin Lotfi +4 more
wiley +1 more source
ATF4/SCO2 Inhibits Ferroptosis in Lung Cancer Through Activating the MAPK Signaling Pathway
ATF4 activates the transcription of SCO2 to increase SCO2 expression that further stimulates p38/ERK1 signals in MAPK pathway, ultimately promoting proliferation and migration while inhibiting apoptosis and ferroptosis of lung cancer cells. ABSTRACT Ferroptosis is a specific cell death form resulting from the iron‐dependent lipid peroxidation ...
Liang Yu +6 more
wiley +1 more source
The dual role of leukotrienes in the tumor microenvironment: balancing pro-tumorigenic and anti-tumor immunity. [PDF]
Thake A +3 more
europepmc +1 more source

