Results 91 to 100 of about 923,622 (282)
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Liquid-liquid phase separation driven by charge heterogeneity
Communications PhysicsDespite the intrinsic charge heterogeneity of proteins plays a crucial role in the liquid-liquid phase separation (LLPS) of a broad variety of protein systems, our understanding of the effects of their electrostatic anisotropy is still in its early ...
Daniele Notarmuzi, Emanuela Bianchi
doaj +1 more source
Ferromagnetism-induced Phase Separation in a Two-dimensional Spin Fluid [PDF]
, 2019 We study the liquid-gas phase separation observed in a system of repulsive particles dressed with ferromagnetically aligning spins, a so-called `spin fluid'.
Casiulis, Mathias +3 more
core +1 more source
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Oxygen in the Earth's core: a first principles study [PDF]
, 1998 First principles electronic structure calculations based on density functional theory have been used to study the thermodynamic, structural and transport properties of solid solutions and liquid alloys of iron and oxygen at Earth's core conditions.
Alfe`, Dario +2 more
core +2 more sources
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Molecular Dynamics Simulation of Binary liquid mixture Phase Separation and Glass Transition
Chemical Engineering Transactions, 2018 This paper aims to study the phase separation of binary liquid mixture and two-phase glass transition process by using the method of molecular dynamics (MD) simulation.
Meili Li, Xingye Fu
doaj +1 more source
Liquid-liquid phase separation by nucleation and growth in solutions of poly(2,6 dimethyl-1,4 phenylene oxide) in toluene [PDF]
, 1973 In solutions of poly(2,6 dimethyl-1,4 phenylene oxide) in toluene, the nucleation of the newly formed phase during liquid-liquid phase separation takes place after induction periods which vary between several minutes (at temperatures close to the ...
Emmerik, P.T. van, Smolders, C.A.
core +2 more sources
FEBS Open Bio, EarlyView.Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda +12 more
wiley +1 more source