Results 81 to 90 of about 6,019,478 (263)

Novel liquid phase separation techniques for proteome study

open access: yes, 2008
Novel liquid phase separation techniques for proteome ...
张玉奎
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Evaluation of Electro-Optic Behaviour of Chiral Smetic Liquid Crystals Dispalys with V-shaped response [PDF]

open access: yes, 2003
In the last years, chiral smectic liquid crystals with V-shaped electro-optic response have been reported as one of the most promising technologies for display applications.
Urruchi del Pozo, Virginia   +3 more
core   +2 more sources

Driving Forces of Liquid–Liquid Phase Separation in Biological Systems

open access: yesBiomolecules, 2019
Analysis of liquid−liquid phase separation in biological systems shows that this process is similar to the phase separation observed in aqueous two-phase systems formed by nonionic polymers, proteins, and polysaccharides.
Boris Y. Zaslavsky   +2 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Separation of p-Nitrophenol and o-Nitrophenol with three-liquid-phase extraction system

open access: yes, 2009
Three-liquid-phase systems containing polyethylene glycol with different molecular weight were explored to investigate the partitioning behavior of simulated wastewater-containing isomers of p-Nitrophenol (p-NP) and o-Nitrophenot (o-NP). The distribution
Yu, Pinhua   +7 more
core   +1 more source

Active liquid-liquid phase separation in a confining environment

open access: yesPhysical Review E
Active liquid-liquid phase separation (LLPS) in a confining environment is believed to play an important role in cell biology. Recently, it was shown that when active noise at the microscopic level is included in the classical theory of nucleation and growth then this does not cause the breakdown of detailed balance at the \textit{macroscopic} level ...
Chen Lin, Robijn Bruinsma
openaire   +3 more sources

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Voltage programmable liquid optical devices [PDF]

open access: yes, 2009
In this study I have looked at two types of voltage programmable liquid optical device. The first is a rotatable liquid crystal waveplate and the second is an amplitude programmable liquid phase grating. The rotatable waveplate was created by confining a
Wells, GG, Wells, Gary George
core  

Liquid–liquid phase separation of LARP7 restrains HIV-1 replication

open access: yesEMBO Reports
HIV-1 initiates replication by its transactivator Tat, hijacking the positive transcription elongation factor b (P-TEFb) in the host cell. Most P-TEFb is maintained in an inactive state by 7SK snRNP until it is brought to the transcription initiation ...
Zhuoxin Li   +18 more
doaj   +1 more source

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