Results 121 to 130 of about 342,327 (294)

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Electrically tunable polarisation-independent blue-phase liquid crystal binary phase grating via phase-separated composite films [PDF]

, 2017
A simple method for fabricating polarisation-independent blue-phase liquid crystal phase grating is demonstrated by implementing photopolymerisation-induced phase separation through a binary photomask. The dynamic focusing property of the proposed liquid
Avci, Nejmettin, Hwang, Shug June, Avcı, Nejmettin, Nejmettin Avci, Hwang, Shug-June, Shug-June Hwang   +5 more
core   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Evaluation and Application of Stationary Phase Selectivity for Drug Analysis [PDF]

Despite the wide range of HPLC stationary phases available for reversed-phase high-performance liquid chromatography (RP-HPLC) and the in-depth studies using probes to highlight differences between them, there is very little in the way of stationary ...
Perera, R. Wimal H.
core  

Monitoring of liquid flow through microtubes using a micropressure sensor [PDF]

, 2009
The pressure-driven liquid flow through microtubes was studied in a range of very low Reynolds numbers (<0.15) by monitoring the pressure change in situ. Cylindrical microtubes with diameters ranging from 50 ?m to 500 ?m were examined and two types of
Zhang, Xunli, Fletcher, Paul D.I., Haswell, Stephen J., Coupland, Paul   +3 more
core   +1 more source

Liquid–Liquid Phase Separation in Hereditary Hearing Loss

Neuroscience Bulletin
Hearing loss is one of the most prevalent sensory disorders affecting the human nervous system. Liquid-liquid phase separation (LLPS) is a physiological process that facilitates the reversible and dynamic assembly of biomolecular condensates. Increasing evidence suggests that LLPS plays a significant role in the pathogenesis of hereditary hearing loss.
Kefan Tao, Yanjun Zong, Xiaozhou Liu, Xinyu Shi, Zhengdong Zhao, Yu Sun   +5 more
openaire   +2 more sources

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Separation of structurally similar protoberberine alkaloids from Corydalis yanhusuo W.T.Wang in reversed-phase high-performance liquid chromatography with chaotropic salts [PDF]

, 2011
Separation of structurally similar protoberberine alkaloids from Corydalis yanhusuo W.T.Wang in reversed-phase high-performance liquid chromatography with chaotropic ...
杜娜娜, 梁鑫淼, 郭志谋, 张秀莉, 王超然   +4 more
core  

Liquid-liquid crystalline phase separation of spider silk proteins

Communications Chemistry
Liquid-liquid phase separation (LLPS) of proteins can be considered an intermediate solubility regime between disperse solutions and solid fibers.
Michael Landreh, Hannah Osterholz, Gefei Chen, Stefan D. Knight, Anna Rising, Axel Leppert   +5 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source