CSDE1 promotes viral immune evasion through RNA-dependent and phosphorylation-modulated liquid-liquid phase separation. [PDF]
Zheng Y +9 more
europepmc +1 more source
Liquid-liquid phase separation-related gene signature characterizes prognostic subtypes and therapeutic sensitivities in gastric cancer. [PDF]
Yan B, Lao Q, Lin L.
europepmc +1 more source
Assessing the performance of multimodal large language models in experimental information extraction from liquid-liquid phase separation literature. [PDF]
Chin KY, Fujii S, Ishida S, Terayama K.
europepmc +1 more source
Lactate-Induced Liquid-Liquid Phase Separation of HIF-1α Drives Myeloid Cell Polarization and Immune Evasion in Colorectal Cancer. [PDF]
Fu C +14 more
europepmc +1 more source
Prediction of liquid-liquid phase separation proteins based on protein language model. [PDF]
Li W, Deng X, Xiang C, Shen H, Zhang Y.
europepmc +1 more source
Correction to "Mechanisms and Pathological Significance of Liquid-Liquid Phase Separation in Bacteria". [PDF]
europepmc +1 more source
Liquid–Liquid Phase Separation in Crowded Environments [PDF]
Biomolecular condensates play a key role in organizing cellular fluids such as the cytoplasm and nucleoplasm. Most of these non-membranous organelles show liquid-like properties both in cells and when studied in vitro through liquid–liquid phase separation (LLPS) of purified proteins.
Alain André, Evan Spruijt
exaly +4 more sources
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Liquid-Liquid Phase Separation in Biology
Annual Review of Cell and Developmental Biology, 2014Cells organize many of their biochemical reactions in non-membrane compartments. Recent evidence has shown that many of these compartments are liquids that form by phase separation from the cytoplasm. Here we discuss the basic physical concepts necessary to understand the consequences of liquid-like states for biological functions.
Christoph A Weber +2 more
exaly +6 more sources
Liquid-liquid Phase Separation in Viral Function
Journal of Molecular Biology, 2023An emerging set of results suggests that liquid-liquid phase separation (LLPS) is the basis for the formation of membrane-less compartments in cells. Evidence is now mounting that various types of virus-induced membrane-less compartments and organelles are also assembled via LLPS.
Xiaoyue, Zhang +3 more
openaire +2 more sources
Modeling Elastically Mediated Liquid-Liquid Phase Separation [PDF]
We propose a continuum theory of the liquid-liquid phase separation in an elastic network where phase-separated microscopic droplets rich in one fluid component can form as an interplay of fluids mixing, droplet nucleation, network deformation, thermodynamic fluctuation, \emph{etc}.
Yanting Wang +2 more
exaly +4 more sources

