Results 221 to 230 of about 6,019,478 (263)

CSDE1 promotes viral immune evasion through RNA-dependent and phosphorylation-modulated liquid-liquid phase separation. [PDF]

open access: yesNat Commun
Zheng Y   +9 more
europepmc   +1 more source

Lactate-Induced Liquid-Liquid Phase Separation of HIF-1α Drives Myeloid Cell Polarization and Immune Evasion in Colorectal Cancer. [PDF]

open access: yesCell Prolif
Fu C   +14 more
europepmc   +1 more source

Liquid–Liquid Phase Separation in Crowded Environments [PDF]

open access: yesInternational Journal of Molecular Sciences, 2020
Biomolecular condensates play a key role in organizing cellular fluids such as the cytoplasm and nucleoplasm. Most of these non-membranous organelles show liquid-like properties both in cells and when studied in vitro through liquid–liquid phase separation (LLPS) of purified proteins.
Alain André, Evan Spruijt
exaly   +4 more sources
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Liquid-Liquid Phase Separation in Biology

Annual Review of Cell and Developmental Biology, 2014
Cells organize many of their biochemical reactions in non-membrane compartments. Recent evidence has shown that many of these compartments are liquids that form by phase separation from the cytoplasm. Here we discuss the basic physical concepts necessary to understand the consequences of liquid-like states for biological functions.
Christoph A Weber   +2 more
exaly   +6 more sources

Liquid-liquid Phase Separation in Viral Function

Journal of Molecular Biology, 2023
An emerging set of results suggests that liquid-liquid phase separation (LLPS) is the basis for the formation of membrane-less compartments in cells. Evidence is now mounting that various types of virus-induced membrane-less compartments and organelles are also assembled via LLPS.
Xiaoyue, Zhang   +3 more
openaire   +2 more sources

Modeling Elastically Mediated Liquid-Liquid Phase Separation [PDF]

open access: yesPhysical Review Letters, 2020
We propose a continuum theory of the liquid-liquid phase separation in an elastic network where phase-separated microscopic droplets rich in one fluid component can form as an interplay of fluids mixing, droplet nucleation, network deformation, thermodynamic fluctuation, \emph{etc}.
Yanting Wang   +2 more
exaly   +4 more sources

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