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Liquid Biopsy in Neurological Diseases [PDF]

open access: yesCells, 2023
The most recent and non-invasive approach for studying early-stage biomarkers is liquid biopsy. This implies the extraction and analysis of non-solid biological tissues (serum, plasma, saliva, urine, and cerebrospinal fluid) without undergoing invasive ...
S. Malhotra   +4 more
semanticscholar   +6 more sources

The Liquid Biopsy Consortium: Challenges and opportunities for early cancer detection and monitoring [PDF]

open access: yesCell Reports Medicine, 2023
The emerging field of liquid biopsy stands at the forefront of novel diagnostic strategies for cancer and other diseases. Liquid biopsy allows minimally invasive molecular characterization of cancers for diagnosis, patient stratification to therapy, and ...
S. Batool   +47 more
semanticscholar   +3 more sources

Liquid biopsy and glioblastoma

open access: yesExploration of Targeted Anti-tumor Therapy, 2023
Glioblastoma is the most common and malignant primary brain tumor. Despite a century of research efforts, the survival of patients has not significantly improved.
R. Eibl, M. Schneemann
semanticscholar   +4 more sources

Liquid Biopsy in Glioblastoma [PDF]

open access: yesCancers, 2022
Simple Summary Glioblastoma is the most common and malignant primary brain tumor. Despite intensive research for new treatments, the survival of patients has not significantly improved in recent decades.
Lorian Ronvaux   +7 more
semanticscholar   +6 more sources

Liquid Biopsies in Multiple Myeloma [PDF]

open access: yes, 2018
Multiple myeloma is the second most common hematological malignancy. It is a heterogeneous disease characterized by focal lesions of malignant plasma cells in the bone marrow.
Sedlarikova, Lenka   +3 more
core   +5 more sources

R-Score: A New Parameter to Assess the Quality of Variants’ Calls Assessed by NGS Using Liquid Biopsies

open access: yesBiology, 2021
Next-generation sequencing (NGS) has enabled a deeper knowledge of the molecular landscape in non-small cell lung cancer (NSCLC), identifying a growing number of targetable molecular alterations in key genes.
Roberto Serna-Blasco   +6 more
doaj   +1 more source

Liquid Biopsy for Lung Cancer: Up-to-Date and Perspectives for Screening Programs

open access: yesInternational Journal of Molecular Sciences, 2023
Lung cancer is the deadliest cancer worldwide. Tissue biopsy is currently employed for the diagnosis and molecular stratification of lung cancer. Liquid biopsy is a minimally invasive approach to determine biomarkers from body fluids, such as blood ...
G. Casagrande   +3 more
semanticscholar   +1 more source

Diagnostic value of liquid biopsy in the era of precision medicine: 10 years of clinical evidence in cancer

open access: yesExploration of Targeted Anti-tumor Therapy, 2023
Liquid biopsy is a diagnostic repeatable test, which in last years has emerged as a powerful tool for profiling cancer genomes in real-time with minimal invasiveness and tailoring oncological decision-making.
V. Caputo   +5 more
semanticscholar   +1 more source

Increased Drp1 promotes autophagy and ESCC progression by mtDNA stress mediated cGAS-STING pathway

open access: yesJournal of Experimental & Clinical Cancer Research, 2022
Background Mitochondrial dynamics homeostasis is important for cell metabolism, growth, proliferation, and immune responses. The critical GTPase for mitochondrial fission, Drp1 is frequently upregulated in many cancers and is closely implicated in ...
Yujia Li   +14 more
doaj   +1 more source

Cancer as an infective disease: the role of EVs in tumorigenesis

open access: yesMolecular Oncology, 2023
Cancer is conventionally considered an evolutionary disease where tumor cells adapt to the environment and evolve eventually leading to the formation of metastasis through the seeding and growth of metastasis‐initiating cells in distant organs.
Lucia Robado de Lope   +4 more
doaj   +1 more source

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