Results 101 to 110 of about 201,821 (348)

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

FEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar, Michael A. Ripperger, Grant M. Westlake, Kevin C. Ess   +3 more
wiley   +1 more source

Diagnostic accuracy of sonohysterography vs hysteroscopy in benign uterine endocavitary findings [PDF]

, 2015
OBJECTIVE: To compare diagnostic accuracy of sonohysterography vs hysteroscopy in patients with benign uterine endocavitary findings. PATIENTS AND METHODS: This retrospective study evaluated 202 patients submitted to sonohysterography after transvaginal ...
Bianchi, Paola, Caserta, Donatella, Catalano, Angelica, Cozza, Giuliana, DI PROPERZIO, Matilde, Frega, Antonio, Gentile, M, Manzara, F, Marziani, Rosalia, Milazzo, Gn, Schimberni, Mauro, Torcia, Francesco, Zinna, M   +12 more
core  

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Does ursodeoxycholic acid change the proliferation of the colorectal mucosa? A randomized, placebo-controlled study [PDF]

, 2003
Background: In animal models ursodeoxycholic acid (UDCA) showed a chemoprotective effect against colon cancer. To explain this, a reduced proliferation of the colorectal mucosal proliferation was suggested.
Diebold, J., Göke, B., Hay, U., Marsteller, I., Ochsenkühn, Thomas, Paumgartner, Gustav, Sackmann, M.   +6 more
core   +1 more source

Sensitivity and optimal clinicopathological features for mutation-targeted liquid biopsy in pN0M0 EGFR-mutant lung adenocarcinoma

, 2021
Masaoki Ito, Yoshihiro Miyata, Shoko Hirano, Fumiko Irisuna, Kei Kushitani, Yuichiro Kai, Naoto Kishi, Yasuhiro Tsutani, Yukio Takeshima, Morihito Okada   +9 more
openalex   +2 more sources

SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas, Pablo Iruzubieta, Alberto Damborenea, Laura Pérez‐Fernández, Inmaculada Azorín, Juan Carlos Jiménez García, Ana Töpf, Pilar Martí, Lorena Fores‐Toribio, María Manterola, Rosana Blanco‐Mañez, Oihane Pikatza‐Menoio, Sonia Alonso‐Martín, Volker Straub, Aitziber L. Cortajarena, Adolfo López de Munain, David De Sancho, Lorea Blázquez, Juan J. Vilchez   +18 more
wiley   +1 more source

Afatinib for Advanced Non-small Cell Lung Cancer in a Case With an Uncommon Epidermal Growth Factor Receptor Mutation (G719A) Identified in the Cerebrospinal Fluid

Frontiers in Oncology, 2019
Few previous studies of patients with non-small cell lung cancer (NSCLC) and leptomeningeal metastases have used liquid biopsy of cerebrospinal fluid (CSF) to identify epidermal growth factor receptor (EGFR) mutations and guide therapy.
Chunhua Ma, Chuoji Huang, Chuoji Huang, Dongjiang Tang, Dongjiang Tang, Xin Ye, Xin Ye, Zhi Li, Renzhong Liu, Ning Mu, Jing Li, Rong Jiang, Juncheng Zhang, Juncheng Zhang   +13 more
doaj   +1 more source

Functional imaging and circulating biomarkers of response to regorafenib in treatment-refractory metastatic colorectal cancer patients in a prospective phase II study [PDF]

, 2018
open32Regorafenib demonstrated efficacy in patients with metastatic colorectal cancer (mCRC). Lack of predictive biomarkers, potential toxicities and cost-effectiveness concerns highlight the unmet need for better patient selection.openKhan, Khurum; Rata,

core   +1 more source

P1281: LIQUID BIOPSY PROVIDES COMPLEMENTARY INFORMATION TO TISSUE BIOPSIES FOR THE MOLECULAR CLASSIFICATION OF DLBCL PATIENTS

, 2022
R. Moia, C. Favini, D. Talotta, Sudhirvarma Sagiraju, R. Bruna, R. Dondolin, Irene Della Starza, R. Soscia, A. Andorno, F. Mercalli, C. Deambrogi, S. Rasi, L. Petrucci, T. Bellissimo, R. Luciano Boldorini, A. Di Rocco, I. Del Giudice, M. Martelli, R. Foà, Gianluca Gaïdano   +19 more
openalex   +1 more source

Supplementary Data from Phase II Study of Ponatinib in Advanced Gastrointestinal Stromal Tumors: Efficacy, Safety, and Impact of Liquid Biopsy and Other Biomarkers [PDF]

, 2023
Suzanne George, Margaret von Mehren, Jonathan A. Fletcher, Jichao Sun, Sen Zhang, Justin R. Pritchard, John Hodgson, David Kerstein, Victor M. Rivera, Frank G. Haluska, Michael C. Heinrich   +10 more
openalex   +1 more source