Results 81 to 90 of about 5,116,830 (334)

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Liquid biopsy in cancer: current status, challenges and future prospects

Signal Transduction and Targeted Therapy
Cancer has a high mortality rate across the globe, and tissue biopsy remains the gold standard for tumor diagnosis due to its high level of laboratory standardization, good consistency of results, relatively stable samples, and high accuracy of results ...
Li-Wei Ma, Huiling Guo, Yun-Xiang Zhao, Zhi-Bo Liu, Chen-Ran Wang, Jia-Hao Bu, Ting Sun, Jian-Wei Wei   +7 more
semanticscholar   +1 more source

Liquid biopsy-detecting molecular targets in cancer management

, 2022
Liquid biopsies are newer diagnostic tests conducted on blood samples to detect biomarkers shed by tumors, such as cancer cells or portion of tumor DNA.
Nithya Ravindran
core   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Longitudinal liquid biopsy alongside positron emission tomography‐computed tomography surveillance in p16‐positive oropharyngeal squamous cell carcinoma: A translational case study

Clinical and Translational Discovery
Background Post‐treatment surveillance of p16‐positive oropharyngeal squamous cell carcinoma (OPSCC) relies on clinical assessment and fluorodeoxyglucose positron emission tomographycomputed tomography (FDG PET‐CT). Longitudinal liquid biopsy may provide
Sreedevi Damodaran, Chameera Ekanayake Weeramange, Lizbeth Kenny, Sarju Vasani, Omar Breik, Touraj Taheri, Paul Leo, Brett G. M. Hughes, Chamindie Punyadeera   +8 more
doaj   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Complementary Breath Profiling Using eNose and Gas Chromatography‐Mass Spectrometry for Noninvasive Triage of Indeterminate Pulmonary Nodules

MedComm
Breath analysis may improve the noninvasive triage of CT‐detected pulmonary nodules. We prospectively evaluated two complementary breath platforms, an electronic nose (eNose) and gas chromatography‐mass spectrometry (GC‐MS), in patients with newly ...
Waqar Ahmed Afridi, Gunter Hartel, Xi Zhang, David Pass, David Fielding, Chamindie Punyadeera   +5 more
doaj   +1 more source

Cancer in a drop: Liquid biopsy highlights from the American Society of Clinical Oncology (ASCO) 2025 annual congress

The Journal of Liquid Biopsy
Over the past decade, liquid biopsy has progressively expanded its role in oncology, supported by mounting evidence demonstrating an increasing number of clinical applications.
Canio Martinelli, Roberto Borea, Maheswaran Shivahamy, Angelo Dipasquale, Erick F. Saldanha, Nadia Ghazali, Eleonora Nicolo, Pavel Stejskal, Letizia Pontolillo, Carolina Reduzzi   +9 more
doaj   +1 more source

Liquid biopsy in breast cancer: Redefining precision medicine

The journal of liquid biopsy
Breast cancer (BC) is the most frequent cancer and the leading cause of cancer-related death among women worldwide. It represents a heterogeneous group of diseases with distinct morphological, immunophenotypic, and molecular profiles, which significantly
Maria Luisa Schiavone, R. Scarpitta, Francesco Ravera, S. Bleve, C. Reduzzi, Federico di Cocco, Martina Dameri, G. Zoppoli, A. Naccarato, P. Nuzzo, M. Cristofanilli, G. Fanelli, C. Scatena   +12 more
semanticscholar   +1 more source

lottaer/liquid-biopsy-denoising: v.1.0.0

Code for the thesis "Deconvolution methods for quantifying copy number variations in liquid biopsy ...
Lotta Eriksson, linneahallin
core   +1 more source