Results 11 to 20 of about 2,946,879 (341)

Liquid biopsy techniques and pancreatic cancer: diagnosis, monitoring, and evaluation

open access: yesMolecular Cancer, 2023
Pancreatic cancer (PC) is one of the most common malignancies. Surgical resection is a potential curative approach for PC, but most patients are unsuitable for operations when at the time of diagnosis.
Kangchun Wang   +3 more
semanticscholar   +1 more source

Machine Learning Characterization of Cancer Patients-Derived Extracellular Vesicles using Vibrational Spectroscopies [PDF]

open access: yesApplied Intelligence (2022), 2021
The early detection of cancer is a challenging problem in medicine. The blood sera of cancer patients are enriched with heterogeneous secretory lipid bound extracellular vesicles (EVs), which present a complex repertoire of information and biomarkers, representing their cell of origin, that are being currently studied in the field of liquid biopsy and ...
arxiv   +1 more source

Cancer metabolites: promising biomarkers for cancer liquid biopsy

open access: yesBiomarker Research, 2023
Cancer exerts a multitude of effects on metabolism, including the reprogramming of cellular metabolic pathways and alterations in metabolites that facilitate inappropriate proliferation of cancer cells and adaptation to the tumor microenvironment.
Wenxiang Wang   +5 more
semanticscholar   +1 more source

Liquid biopsy on the horizon in immunotherapy of non-small cell lung cancer: current status, challenges, and perspectives

open access: yesCell Death and Disease, 2023
Non-small cell lung cancer (NSCLC) is one of the most threatening malignancies to human health and life. In most cases, patients with NSCLC are already at an advanced stage when they are diagnosed.
Yingtao Yang   +6 more
semanticscholar   +1 more source

Flow Rate Independent Multiscale Liquid Biopsy for Precision Oncology [PDF]

open access: yes, 2022
Immunoaffinity-based liquid biopsies of circulating tumor cells (CTCs) hold great promise for cancer management, but typically suffer from low throughput, relative complexity and post-processing limitations. Here we address these issues simultaneously by decoupling and independently optimizing the nano-, micro- and macro-scales of an enrichment device ...
arxiv   +1 more source

AIFM2 promotes hepatocellular carcinoma metastasis by enhancing mitochondrial biogenesis through activation of SIRT1/PGC-1α signaling

open access: yesOncogenesis, 2023
AIFM2 is a crucial NADH oxidase involved in the regulation of cytosolic NAD+. However, the role of AIFM2 in the progression of human cancers remains largely unexplored.
Sanxing Guo   +14 more
doaj   +1 more source

Diagnostic value of liquid biopsy in the era of precision medicine: 10 years of clinical evidence in cancer

open access: yesExploration of Targeted Anti-tumor Therapy, 2023
Liquid biopsy is a diagnostic repeatable test, which in last years has emerged as a powerful tool for profiling cancer genomes in real-time with minimal invasiveness and tailoring oncological decision-making.
V. Caputo   +5 more
semanticscholar   +1 more source

Liquid biopsy at the frontier in renal cell carcinoma: recent analysis of techniques and clinical application

open access: yesMolecular Cancer, 2023
Renal cell carcinoma (RCC) is a major pathological type of kidney cancer and is one of the most common malignancies worldwide. The unremarkable symptoms of early stages, proneness to postoperative metastasis or recurrence, and low sensitivity to ...
Mingyang Li   +6 more
semanticscholar   +1 more source

Liquid biopsy epigenomic profiling for cancer subtyping

open access: yesNature Network Boston, 2023
In a large multi-cancer cohort, a single liquid biopsy assay enables the detection of four epigenomic modifications, allowing the monitoring of expression of potential drug targets and resistance genes.
S. Baca   +42 more
semanticscholar   +1 more source

Toward Personalized Nanomedicine: The Critical Evaluation of Micro and Nanodevices for Cancer Biomarker Analysis in Liquid Biopsy.

open access: yesSmall, 2023
Liquid biopsy for the analysis of circulating cancer biomarkers (CBs) is a major advancement toward the early detection of cancer. In comparison to tissue biopsy techniques, liquid biopsy is relatively painless, offering multiple sampling opportunities ...
Kimberley Clack   +5 more
semanticscholar   +1 more source

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