Results 11 to 20 of about 3,006,723 (410)
Liquid biopsy and glioblastoma
Exploration of Targeted Anti-tumor Therapy, 2023 Glioblastoma is the most common and malignant primary brain tumor. Despite a century of research efforts, the survival of patients has not significantly improved.
R. Eibl, M. Schneemann
semanticscholar +4 more sources
Liquid Biopsy in Neurological Diseases
Cells, 2023 The most recent and non-invasive approach for studying early-stage biomarkers is liquid biopsy. This implies the extraction and analysis of non-solid biological tissues (serum, plasma, saliva, urine, and cerebrospinal fluid) without undergoing invasive ...
S. Malhotra +4 more
semanticscholar +5 more sources
Liquid Biopsy in Glioblastoma [PDF]
Cancers, 2022 Glioblastoma (GBM) is the most common and aggressive primary brain tumor. Despite recent advances in therapy modalities, the overall survival of GBM patients remains poor. GBM diagnosis relies on neuroimaging techniques. However, confirmation via histopathological and molecular analysis is necessary.
Lorian Ronvaux +7 more
openaire +4 more sources
Lung Cancer Management, 2016 In the era of high-throughput molecular screening and personalized medicine, difficulty in determining whether cancer mutations are truly 'actionable' remains a gray zone in NSCLC. The most important prerequisite to perform such investigations is the tumor tissue retrieval via biopsy at diagnosis and after occurrence of resistance.
Trombetta, D. +3 more
openaire +2 more sources
A lab-on-a-disc platform enables serial monitoring of individual CTCs associated with tumor progression during EGFR-targeted therapy for patients with NSCLC [PDF]
, 2020 Rationale: Unlike traditional biopsy, liquid biopsy, which is a largely non-invasive diagnostic and monitoring tool, can be performed more frequently to better track tumors and mutations over time and to validate the efficiency of a cancer treatment ...
Cho, Yoon-Kyoung +9 more
core +1 more source
Liquid Biopsy for Lung Cancer: Up-to-Date and Perspectives for Screening Programs
International Journal of Molecular Sciences, 2023 Lung cancer is the deadliest cancer worldwide. Tissue biopsy is currently employed for the diagnosis and molecular stratification of lung cancer. Liquid biopsy is a minimally invasive approach to determine biomarkers from body fluids, such as blood ...
G. Casagrande +3 more
semanticscholar +1 more source
Liquid biopsies and cancer omics [PDF]
Cell Death Discovery, 2020 AbstractThe development of the sequencing technologies allowed the generation of huge amounts of molecular data from a single cancer specimen, allowing the clinical oncology to enter the era of the precision medicine. This massive amount of data is highlighting new details on cancer pathogenesis but still relies on tissue biopsies, which are unable to ...
Yufang Shi +25 more
openaire +6 more sources
Liquid biopsy techniques and pancreatic cancer: diagnosis, monitoring, and evaluation
Molecular Cancer, 2023 Pancreatic cancer (PC) is one of the most common malignancies. Surgical resection is a potential curative approach for PC, but most patients are unsuitable for operations when at the time of diagnosis.
Kangchun Wang +3 more
semanticscholar +1 more source
Oncogenesis, 2023 AIFM2 is a crucial NADH oxidase involved in the regulation of cytosolic NAD+. However, the role of AIFM2 in the progression of human cancers remains largely unexplored.
Sanxing Guo +14 more
doaj +1 more source
Liquid biopsy epigenomic profiling for cancer subtyping
Nature Network Boston, 2023 In a large multi-cancer cohort, a single liquid biopsy assay enables the detection of four epigenomic modifications, allowing the monitoring of expression of potential drug targets and resistance genes.
S. Baca +42 more
semanticscholar +1 more source