Results 11 to 20 of about 201,821 (348)
Medizinische Genetik, 2016 Zusammenfassung „Liquid Biopsy“ bezieht sich in der Onkologie auf die Untersuchung von zirkulierenden Tumorzellen (engl.: circulating tumor cells [CTCs]) oder zirkulierender Tumor-DNA (engl.: circulating tumor DNA [ctDNA]), um nicht invasiv aus dem peripheren Blut Charakteristika über das Tumorgenom von Krebspatienten zu erfassen.
Michael R. Speicher +2 more
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, 2023 New ways of looking at tumor genetics and dynamics have been developed: the Liquid Biopsy (LB), which has been incorporated into clinical practice as a noninvasive analysis of circulating material derived from tumors, which represents an innovative tool in precision oncology and overcomes the current limitations associated with tissue biopsies.
Valeria Denninghoff, Maria Jose Serrano
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Liquid biopsy and glioblastoma
Exploration of Targeted Anti-tumor Therapy, 2022 Glioblastoma is the most common and malignant primary brain tumor. Despite a century of research efforts, the survival of patients has not significantly improved. Currently, diagnosis is based on neuroimaging techniques followed by histopathological and molecular analysis of resected or biopsied tissue.
Robert Eibl, Markus Schneemann
openaire +3 more sources
Lung Cancer Management, 2016 In the era of high-throughput molecular screening and personalized medicine, difficulty in determining whether cancer mutations are truly 'actionable' remains a gray zone in NSCLC. The most important prerequisite to perform such investigations is the tumor tissue retrieval via biopsy at diagnosis and after occurrence of resistance.
Trombetta, D. +3 more
openaire +2 more sources
Journal of biological regulators and homeostatic agents, 2019 During the early formation and growth of primary tumor (e.g., breast, colon, or prostate cancer), cells are shed from the primary tumor and then circulate through the bloodstream. Many of the major recent advances in targeted therapies have relied on the acquisition of tumor tissue via biopsy before initiation of therapy or after the onset of ...
Candotto, V +5 more
+9 more sources
Genes, Chromosomes and Cancer, 2019 AbstractLiquid biopsy is based on minimally invasive blood tests and has a high potential to significantly change the therapeutic strategy in cancer patients, providing an extremely powerful and reliable noninvasive clinical tool for the individual molecular profiling of patients in real time.
Evi Lianidou, Klaus Pantel
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Liquid Biopsy in Glioblastoma [PDF]
Cancers, 2022 Glioblastoma (GBM) is the most common and aggressive primary brain tumor. Despite recent advances in therapy modalities, the overall survival of GBM patients remains poor. GBM diagnosis relies on neuroimaging techniques. However, confirmation via histopathological and molecular analysis is necessary.
Lorian Ronvaux +7 more
openaire +4 more sources
Frontiers in Molecular Biosciences, 2021 The high incidence and mortality of lung cancer make early detection of lung cancer particularly important. At present, the diagnosis of lung cancer mainly depends on diagnostic imaging and tissue biopsy. However, current diagnostics are not satisfactory
Lanxiang Huang +11 more
doaj +1 more source
Focused ultrasound-enabled brain tumor liquid biopsy [PDF]
, 2018 Although blood-based liquid biopsies have emerged as a promising non-invasive method to detect biomarkers in various cancers, limited progress has been made for brain tumors.
Chen, Hong +10 more
core +3 more sources