Results 241 to 250 of about 3,006,723 (410)

Digital Bioassays on the Slipchip Microfluidic Devices

Advanced Sensor Research, EarlyView.
This review summarizes recent advances in SlipChip‐based digital bioassays, highlighting their simple “load and slip” operation for fluid partitioning which eliminate the need for sophisticated fluidic systems. Applications include digital nucleic acid analysis, digital protein analysis and single‐cell analysis, demonstrating the platform‘s potential ...
Qingqing Luo, Ziqing Yu, Weiyuan Lyu, Yang Luo, Lei Xu, Feng Shen   +5 more
wiley   +1 more source

Liquid Biopsy: The Challenges of a Revolutionary Approach in Oncology. [PDF]

Int J Mol Sci
Coppola CA, De Summa S, Matera G, Pilato B, Traversa D, Tommasi S.   +5 more
europepmc   +1 more source

Advances in Microfluidic Cochlea‐On‐A‐Chip

Advanced Science, EarlyView.
This review systematically examines diverse cell sources for inner ear organoids and outlines stepwise induction protocols. Furthermore, it discusses current applications and prospective developments of cochlea‐on‐a‐chip technologies in areas such as deafness modeling, mechanistic studies, and drug evaluation, with particular focus on gene‐therapy drug
Tian Shen, Shanying Han, Weiwei He, Wen Yang, Xinghua Tang, Xiaolong Zhao, Xinghong Liu, Zhenhua Shao, Lin Cheng, Yu Zhao, Jiangang Fan   +10 more
wiley   +1 more source

Liquid Biopsy in Solid Tumours: An Overview. [PDF]

Cytopathology
Pisapia P, Iaccarino A, Troncone G, Malapelle U.   +3 more
europepmc   +1 more source

Estrogen receptor mutations and splice variants determined in liquid biopsies from metastatic breast cancer patients [PDF]

, 2017
Nick Beije, Anieta M. Sieuwerts, Jaco Kraan, Ngoc M. Van, Wendy Onstenk, Silvia Rita Vitale, Michelle van der Vlugt‐Daane, Luc Dirix, Anja Brouwer, Paul Hamberg, Felix E. de Jongh, Agnes Jager, Caroline Seynaeve, Maurice P.H.M. Jansen, John A. Foekens, John W.M. Martens, Stefan Sleijfer   +16 more
openalex   +1 more source

Alnustone Ameliorates Metabolic Dysfunction‐Associated Steatotic Liver Disease by Facilitating Mitochondrial Fatty Acid β‐Oxidation via Targeting Calmodulin

Advanced Science, EarlyView.
This study identifies alnustone, a natural compound from Alpinia katsumadai, as a potent therapeutic agent for MASLD and MASH. Alnustone enhances mitochondrial fatty acid β‐oxidation by directly targeting calmodulin, improving liver steatosis, fibrosis, and insulin resistance in vivo.
Shourui Hu, Xiaofan Liang, Yiming Qin, Yuxuan Li, Yue Liu, Congcong Liu, Zongxuan Lin, Chunxuan Geng, Yanqi Xu, Daimin Wei, Yingying Qin, Han Zhao, Yuqing Zhang, Zi‐Jiang Chen   +13 more
wiley   +1 more source

Why the Therapeutic Impact of RAS Mutation Clearance in Plasma ctDNA Deserves to Be Further Explored in Metastatic Colorectal Cancer

Frontiers in Oncology, 2019
Chiara Nicolazzo, Francesca Belardinilli, Salvatore Caponnetto, Angela Gradilone, Enrico Cortesi, Giuseppe Giannini, Giuseppe Giannini, Paola Gazzaniga   +7 more
doaj   +1 more source

The LDH‐H3K18La‐Nur77 Axis Potentiates Immune Escape in Small Cell Lung Cancer

Advanced Science, EarlyView.
Lactate from SCLC tumors induces H3K18 lactylation in naïve CD8+ T cells, upregulating Nurr77 and enhancing tonic TCR signaling. This leads to T cell hyporesponsiveness to stimulation, impairing antitumor immunity and reducing immunotherapy efficacy.
Xiaoling Shang, Bo Cheng, Chenyue Zhang, Chenglong Zhao, Ruiqing Wang, Xun Zhang, Dizhi Jiang, Xinyu Zhang, Xinyue Ma, Hongyuan Mao, Zerun Li, Chenhan Huang, Tianzi Wang, Kaiyue Guo, Liwen Wang, Ning Tang, Haiyong Wang   +16 more
wiley   +1 more source

Liquid Biopsy as a Diagnostic and Monitoring Tool in Glioblastoma. [PDF]

Medicina (Kaunas)
Tataranu LG.
europepmc   +1 more source

Liquid biopsy into the clinics: Current evidence and future perspectives

The journal of liquid biopsy
M. Boukovala, C. B. Westphalen, V. Probst   +2 more
semanticscholar   +1 more source