Results 251 to 260 of about 3,006,723 (410)

Noninvasive Assessment of β‐Secretase Activity Through Click Chemistry‐Mediated Enrichment of Neuronal Extracellular Vesicles to Detect Alzheimer's Disease

Advanced Science, EarlyView.
This study presents the NEV β‐secretase activity assay, a groundbreaking method for noninvasive evaluation of β‐secretase activity in Alzheimer's disease (AD) patients, enabling the generation of individualized β‐secretase activity profiles.
Hyoyong Kim, Junseok Lee, Audrey Qian, You‐Ren Ji, Ryan Zhang, Qixin Hu, Christopher Kazu Williams, Han‐Yu Chuang, Matthew D. Smalley, Yaya Xu, Liang Gao, Mary C. Mayo, Ting Zhang, Edwin M. Posadas, Zaldy S. Tan, Harry V. Vinters, Keith Vossel, Shino Magaki, Yazhen Zhu, Hsian‐Rong Tseng   +19 more
wiley   +1 more source

Liquid biopsy in breast cancer: a practical guide for surgeons. [PDF]

Gland Surg
Venkataraman J, Crook T, Mokbel K.
europepmc   +1 more source

Utilizing Tumor and Plasma Liquid Biopsy in Treatment Decision Making for an Estrogen Receptor-Positive Advanced Breast Cancer Patient [PDF]

, 2017
Bing Xu, Amy Krie, Pradip De, Casey Williams, Rachel Elsey, Jessica Klein, Brian Leyland‐Jones   +6 more
openalex   +1 more source

Microphysiological Uremia Model Reveals Biophysical Potentiators of Vascular Dysfunction

Advanced Science, EarlyView.
A microfluidic platform of engineered blood vessels is developed to study the role of mechanical forces in immune cell adhesion and extravasation in uremic microenvironments. Elevated pressure increases monocyte activity, with ICAM‐1 as a key driver. Matrix density influences monocyte phenotypes, but the uremic environment consistently promoted a pro ...
Mitesh Rathod, Ryan N. Stack, Sarah E. Kubik, Stephanie A. Huang, Chloe P. Whitworth, Wen Y. Aw, Elizabeth L. Doherty, Sara M. Meehan, Prabir Roy‐Chaudhury, William J. Polacheck   +9 more
wiley   +1 more source

Tracing the history of clinical practice of liquid biopsy: a bibliometric analysis. [PDF]

Front Immunol
Zhang S, Zhao H, Wang K, Li L, Pan Q, Lu M, Zhang X.   +6 more
europepmc   +1 more source

Detection and characterization of circulating cell free tumor DNA in cancer patients with malignant solid tumors. Liquid biopsy: a new tool in molecular pathology?

, 2016
Tanja Hinrichsen, Juliane K. Dworniczak, Oliver Wachter, Bernd Dworniczak, Barbara Dockhorn‐Dworniczak   +4 more
openalex   +2 more sources

A Dual Approach with Organoid and CRISPR Screening Reveals ERCC6 as a Determinant of Cisplatin Resistance in Osteosarcoma

Advanced Science, EarlyView.
This study utilizes patient‐derived osteosarcoma organoids and CRISPR screening to identify ERCC6 and HNRNPM as key mediators of cisplatin resistance via the PI3K/AKT pathway and BAX alternative splicing. These findings provide novel insights and potential therapeutic targets for overcoming chemoresistance in osteosarcoma.
Ruiling Xu, Sai Zhu, Wenchao Zhang, Haodong Xu, Chao Tu, Honghui Wang, Lu Wang, Na He, Tang Liu, Xiaoning Guo, Xiaolei Ren, Zhihong Li   +11 more
wiley   +1 more source

Impact of Reference Materials for Analytical Performance Evaluation of Liquid Biopsy NGS Assays

The Journal of Liquid Biopsy, 2023
A. Hallermayr, T. Keßler, B. Liesfeld, S. Bernstein, V. Steinke-Lange, T. Neuhann, J. Pickl, E. Holinski-Feder   +7 more
doaj  

Liquid Biopsy-Derived Tumor Biomarkers for Clinical Applications in Glioblastoma. [PDF]

Biomolecules
de Lima BP, Ferraz LS, Devalle S, Borges HL.   +3 more
europepmc   +1 more source

The potential of liquid biopsies for the early detection of cancer [PDF]

, 2017
Ellen Heitzer, Samantha Perakis, Jochen B. Geigl, Michael R. Speicher   +3 more
openalex   +1 more source