Results 21 to 30 of about 113,588 (316)

Dynamic change of metabolic dysfunction-associated steatotic liver disease in chronic hepatitis C patients after viral eradication: A nationwide registry study in Taiwan [PDF]

Clinical and Molecular Hepatology
Background/Aims Steatotic liver disease (SLD) is a common manifestation in chronic hepatitis C (CHC). Metabolic alterations in CHC are associated with metabolic dysfunction-associated steatotic liver disease (MASLD).
Chung-Feng Huang, Chia-Yen Dai, Yi-Hung Lin, Chih-Wen Wang, Tyng-Yuan Jang, Po-Cheng Liang, Tzu-Chun Lin, Pei-Chien Tsai, Yu-Ju Wei, Ming-Lun Yeh, Ming-Yen Hsieh, Chao-Kuan Huang, Jee-Fu Huang, Wan-Long Chuang, Ming-Lung Yu   +14 more
doaj   +1 more source

Dynamic gene screening enabled identification of a 10-gene panel for early detection and progression assessment of gastric cancer

Computational and Structural Biotechnology Journal, 2023
Early diagnosis and progression assessment are critical for the timely detection and treatment of gastric cancer (GC) patients. Identification of diagnostic biomarkers for early detection of GC represents an unmet clinical need, and how these markers ...
Fei Long, Shuo Li, Yaqi Xu, Min Liu, Xuan Zhang, Junting Zhou, Yiyi Chen, Yuan Rong, Xiangyu Meng, Fubing Wang   +9 more
doaj   +1 more source

Long noncoding RNA LINC00662 promotes M2 macrophage polarization and hepatocellular carcinoma progression via activating Wnt/β‐catenin signaling

Molecular Oncology, 2020
Tumor‐associated macrophages have important roles in hepatocellular carcinoma (HCC) initiation and progression. Long noncoding RNAs (lncRNAs) have also been reported to be involved in HCC. In this study, we explored how lncRNA LINC00662 may influence HCC
Xiaohui Tian, Yuanyuan Wu, Yating Yang, Jiaxin Wang, Menglan Niu, Shanjun Gao, Tao Qin, Dengke Bao   +7 more
doaj   +1 more source

Current Status and Future Perspectives of Liquid Biopsy in Small Cell Lung Cancer

Biomedicines, 2021
Approximately 19% of all cancer-related deaths are due to lung cancer, which is the leading cause of mortality worldwide. Small cell lung cancer (SCLC) affects approximately 15% of patients diagnosed with lung cancer.
Patricia Mondelo-Macía, Jorge García-González, Luis León-Mateos, Adrián Castillo-García, Rafael López-López, Laura Muinelo-Romay, Roberto Díaz-Peña   +6 more
doaj   +1 more source

Cost-effectiveness analysis of capecitabine maintenance therapy plus best supportive care vs. best supportive care alone as first-line treatment of newly diagnosed metastatic nasopharyngeal carcinoma

Frontiers in Public Health, 2023
ObjectivesMaintenance therapy with capecitabine after induction chemotherapy for patients with newly diagnosed metastatic nasopharyngeal carcinoma (mNPC) has been confirmed to be effective.
Jiaqi Han, Xiaomeng Lan, Kun Tian, Xi Shen, Jinlan He, Nianyong Chen   +5 more
doaj   +1 more source

Advances in liquid biopsy in neuroblastoma

Fundamental Research, 2022
Even with intensive treatment of high-risk neuroblastoma (NB) patients, half of high-risk NB patients still relapse. New therapies targeting the biological characteristics of NB have important clinical value for the personalized treatment of NB. However, the current biological markers for NB are mainly analyzed by tissue biopsy.
Zhenjian Zhuo, Lei Lin, Lei Miao, Meng Li, Jing He   +4 more
openaire   +3 more sources

Mechanobiology and survival strategies of circulating tumor cells: a process towards the invasive and metastatic phenotype

Frontiers in Cell and Developmental Biology, 2023
Metastatic progression is the deadliest feature of cancer. Cancer cell growth, invasion, intravasation, circulation, arrest/adhesion and extravasation require specific mechanical properties to allow cell survival and the completion of the metastatic ...
Keerthi Kurma, Keerthi Kurma, Keerthi Kurma, Catherine Alix-Panabières, Catherine Alix-Panabières, Catherine Alix-Panabières   +5 more
doaj   +1 more source

The liquid biopsy in lung cancer [PDF]

Genes & Cancer, 2017
The incidence of lung cancer has significantly increased over the last century, largely due to smoking, and remains the most common cause of cancer deaths worldwide. This is often due to lung cancer first presenting at late stages and a lack of curative therapeutic options at these later stages.
Guillermo A. Herrera, Jungmi W. Yun, Rodney E. Shackelford, Youmna E. Moufarrej, Anvesh R. Kompelli, Junaid Ansari, Jonathan Steven Alexander   +6 more
openaire   +3 more sources

Exosomal miRNA profile as complementary tool in the diagnostic and prediction of treatment response in localized breast cancer under neoadjuvant chemotherapy

Breast Cancer Research, 2019
Background Breast cancer patients under neoadjuvant chemotherapy includes a heterogeneous group of patients who eventually develop distal disease, not detectable by current methods.
Alba Rodríguez-Martínez, Diego de Miguel-Pérez, Francisco Gabriel Ortega, José Luis García-Puche, Inmaculada Robles-Fernández, José Exposito, Jordi Martorell-Marugan, Pedro Carmona-Sáez, María del Carmen Garrido-Navas, Christian Rolfo, Hugh Ilyine, José Antonio Lorente, Marta Legueren, María José Serrano   +13 more
doaj   +1 more source

Tyrosine Kinase Inhibitors Could Be Effective Against Non-small Cell Lung Cancer Brain Metastases Harboring Uncommon EGFR Mutations

Frontiers in Oncology, 2020
Background: The significance of uncommon epidermal growth factor receptor (EGFR) mutations in patients with non-small cell lung cancer (NSCLC) and brain metastasis (BM) remains unclear.
Chunhua Ma, Juncheng Zhang, Juncheng Zhang, Dongjiang Tang, Dongjiang Tang, Xin Ye, Xin Ye, Jing Li, Ning Mu, Zhi Li, Renzhong Liu, Liang Xiang, Liang Xiang, Chuoji Huang, Chuoji Huang, Rong Jiang   +15 more
doaj   +1 more source