Results 21 to 30 of about 2,946,879 (341)

Recent advances of liquid biopsy: Interdisciplinary strategies toward clinical decision‐making

Interdisciplinary Medicine, 2023
Liquid biopsy has emerged as a promising avenue for non‐invasive and rapid retrieval of pathological information from patient body fluids. Over the years, liquid biopsy has garnered significant attention for clinically treating cancer by selecting ...
Han Bao, L. Min, Fanqin Bu, Shutao Wang, Jingxin Meng   +4 more
semanticscholar   +1 more source

Circular RNAs Are Promising Biomarkers in Liquid Biopsy for the Diagnosis of Non-small Cell Lung Cancer

Frontiers in Molecular Biosciences, 2021
The high incidence and mortality of lung cancer make early detection of lung cancer particularly important. At present, the diagnosis of lung cancer mainly depends on diagnostic imaging and tissue biopsy. However, current diagnostics are not satisfactory
Lanxiang Huang, Lanxiang Huang, Yuan Rong, Yuan Rong, Xuan Tang, Xuan Tang, Kezhen Yi, Kezhen Yi, Jianyuan Wu, Fubing Wang, Fubing Wang, Fubing Wang   +11 more
doaj   +1 more source

Comprehensive liquid biopsy analysis as a tool for the early detection of minimal residual disease in breast cancer

Scientific Reports, 2023
Liquid biopsy (LB) provides a unique minimally invasive tool to follow-up cancer patients over time, to detect minimal residual disease (MRD), to study metastasis-biology and mechanisms of therapy-resistance.
D. Stergiopoulou, A. Markou, A. Strati, M. Zavridou, E. Tzanikou, Sophia Mastoraki, G. Kallergi, V. Georgoulias, E. Lianidou   +8 more
semanticscholar   +1 more source

Elevated TEFM expression promotes growth and metastasis through activation of ROS/ERK signaling in hepatocellular carcinoma

Cell Death and Disease, 2021
TEFM (transcription elongation factor of mitochondria) has been identified as a novel nuclear-encoded transcription elongation factor in the transcription of mitochondrial genome.
Lixin Wan, Yang Wang, Zijie Zhang, Jiaxin Wang, Menglan Niu, Yuanyuan Wu, Yating Yang, Yongxia Dang, Shuang Hui, Meng Ni, Bo Wan, Dengke Bao   +11 more
doaj   +1 more source

Advances in Liquid Biopsy Technology and Implications for Pancreatic Cancer

International Journal of Molecular Sciences, 2023
Pancreatic cancer is a highly aggressive malignancy with a climbing incidence. The majority of cases are detected late, with incurable locally advanced or metastatic disease.
A. Raufi, Michael S May, M. Hadfield, A. Seyhan, W. El-Deiry   +4 more
semanticscholar   +1 more source

NGS‐based liquid biopsy profiling identifies mechanisms of resistance to ALK inhibitors: a step toward personalized NSCLC treatment

Molecular Oncology, 2021
Despite impressive and durable responses, nonsmall cell lung cancer (NSCLC) patients treated with anaplastic lymphoma kinase (ALK) inhibitors (ALK‐Is) ultimately progress due to development of resistance.
Estela Sánchez‐Herrero, Roberto Serna‐Blasco, Vadym Ivanchuk, Rosario García‐Campelo, Manuel Dómine Gómez, José M. Sánchez, Bartomeu Massutí, Noemi Reguart, Carlos Camps, Sandra Sanz‐Moreno, Silvia Calabuig‐Fariñas, Eloísa Jantus‐Lewintre, Magdalena Arnal, Dietmar Fernández‐Orth, Virginia Calvo, Víctor González‐Rumayor, Mariano Provencio, Atocha Romero   +17 more
doaj   +1 more source

The functional and clinical roles of liquid biopsy in patient-derived models

Journal of Hematology & Oncology, 2023
The liquid biopsy includes the detection of circulating tumor cells (CTCs) and CTC clusters in blood, as well as the detection of, cell-free DNA (cfDNA)/circulating tumor DNA (ctDNA) and extracellular vesicles (EVs) in the patient's body fluid.
Ziqing Zhu, Erya Hu, Hong Shen, Jun Tan, S. Zeng   +4 more
semanticscholar   +1 more source

Liquid Biopsy: An Evolving Paradigm for Non-invasive Disease Diagnosis and Monitoring in Medicine

Cureus, 2023
Liquid biopsy stands as an innovative instrument in the realm of precision medicine, enabling non-invasive disease diagnosis and the early detection of cancer.
Kanishk K Adhit, Anil Wanjari, Sharanya Menon, Siddhaarth K   +3 more
semanticscholar   +1 more source

Enhancing clinical potential of liquid biopsy through a multi-omic approach: A systematic review

Frontiers in Genetics, 2023
In the last years, liquid biopsy gained increasing clinical relevance for detecting and monitoring several cancer types, being minimally invasive, highly informative and replicable over time.
G. Di Sario, Valeria Rossella, Elvira Smeralda Famulari, A. Maurizio, D. Lazarević, Francesca Giannese, C. Felici   +6 more
semanticscholar   +1 more source

Quantitative phase microscopy spatial signatures of cancer cells [PDF]

Cytometry A. 2017 May;91(5):482-493, 2019
We present cytometric classification of live healthy and cancer cells by using the spatial morphological and textural information found in the label-free quantitative phase images of the cells. We compare both healthy cells to primary tumor cell and primary tumor cells to metastatic cancer cells, where tumor biopsies and normal tissues were isolated ...
arxiv   +1 more source