Results 51 to 60 of about 189,052 (363)

Circulating Genetically Abnormal Cells Add Non-Invasive Diagnosis Value to Discriminate Lung Cancer in Patients With Pulmonary Nodules ≤10 mm

Frontiers in Oncology, 2021
BackgroundLung cancer screening using low-dose computed tomography (LDCT) often leads to unnecessary biopsy because of the low specificity among patients with pulmonary nodules ≤10 mm.
Maosong Ye, Xiaoxuan Zheng, Xiaoxuan Zheng, Xin Ye, Xin Ye, Xin Ye, Juncheng Zhang, Juncheng Zhang, Chuoji Huang, Chuoji Huang, Zilong Liu, Meng Huang, Meng Huang, Xianjun Fan, Xianjun Fan, Yanci Chen, Yanci Chen, Botao Xiao, Jiayuan Sun, Jiayuan Sun, Chunxue Bai   +20 more
doaj   +1 more source

Liquid biopsies for bladder cancer [PDF]

Translational Andrology and Urology, 2017
The development of accurate urinary biomarkers for the non-invasive detection of urothelial bladder cancer (UBC) could transform patient pathways by reducing reliance on cystoscopy, and the identification of highly prognostic (or even predictive) biomarkers could better guide patient management.
Richard T. Bryan, Douglas G. Ward
openaire   +3 more sources

Targeting Drp1 inhibits ESCC progression via the ROS-PGC1-α-Nrf1/2 pathway

Journal of Translational Medicine
Background Esophageal squamous cell carcinoma (ESCC) ranks among the most prevalent malignancies of the digestive tract. Due to the absence of obvious symptoms in patients with early-stage ESCC, most cases are diagnosed at advanced stages, highlighting ...
Zhixiong Jiang, Yating Yang, Jinchi Zhou, Xin Li, Qingqing Meng, Xiangyi Yu, Yaxin Xue, Mengyu Li, Yichen Cai, Pengchun Han, Mingjun Jiang, Huizhen Wang, Congrong Liu, Jing Zhao, Lixin Wan, Dengke Bao   +15 more
doaj   +1 more source

DNA Methylation Changes in Human Papillomavirus-Driven Head and Neck Cancers

Cells, 2020
Disruption of DNA methylation patterns is one of the hallmarks of cancer. Similar to other cancer types, human papillomavirus (HPV)-driven head and neck cancer (HNC) also reveals alterations in its methylation profile.
Chameera Ekanayake Weeramange, Kai Dun Tang, Sarju Vasani, Julian Langton-Lockton, Liz Kenny, Chamindie Punyadeera   +5 more
doaj   +1 more source

Cytomegalovirus infection and gastric emptying [PDF]

, 1992
Gastrointestinal infection due to cytomegalovirus occurs frequently in liver transplant recipients. Upper gastrointestinal cytomegalovirus infection is associated with subjective complaints of nausea, a sense of abdominal fullness, and occasionally ...
Chien, MC, Gavaler, JS, Schade, RR, Starzl, TE, Van Thiel, DH   +4 more
core   +1 more source

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

Molecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia, Anouk C. de Jong, Lisanne F. van Dessel, Vanja de Weerd, Corine Beaufort, Jean Helmijr, José Alberto Nakauma‐González, Job van Riet, Paul Hamberg, Daniel Vis, Michiel S. van der Heijden, Nick Beije, Martijn P. Lolkema, Teoman Deger, Saskia M. Wilting, Ronald de Wit, Maurice P. H. M. Jansen, John W. M. Martens   +17 more
wiley   +1 more source

The importance of circulating tumor products as „liquid biopsies” in colorectal cancer [PDF]

, 2018
Liquid biopsies represent an array of plasma analysis tests that are studied to evaluate and identify circulating tumor products, especially circulating tumor cells (CTCs) and circulating tumor DNA (ctDNA).
Calborean, Veronica, Miscoci, Alina, Pirvu, Cristian D., Pădureanu, Vlad, Rogoveanu, Otilia C., Streba, Costin T., Vere, Cristin C.   +6 more
core   +4 more sources

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi, Eric Feng, Nicholas R. Rydzewski, Amy K. Taylor, Jamie M. Sperger, Yue Shi, Kyle T. Helzer, Matthew L. Bootsma, Viridiana Carreno, Alex H. Chang, Luke A. Nunamaker, Grace C. Blitzer, Tianfu Andy Shang, Aishwarya Subramanian, Anders Bjartell, Andreas Josefsson, Pernilla Wikström, Emily Feng, Manish Kohli, Rendong Yang, Scott M. Dehm, Eric J. Small, Rahul Aggarwal, David A. Quigley, Joshua M. Lang, Shuang G. Zhao, Martin Sjöström   +26 more
wiley   +1 more source

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source

The Impact of Steatosis on Chronic Hepatitis C Progression and Response to Antiviral Treatments

Biomedicines, 2021
Metabolic derangement is characteristic in patients with hepatitis C virus (HCV) infection. Aside from established liver injury, various extrahepatic metabolic disorders impact the natural history of the disease, clinical outcomes, and the efficacy of ...
Phumelele Yvonne Siphepho, Yi-Ting Liu, Ciniso Sylvester Shabangu, Jee-Fu Huang, Chung-Feng Huang, Ming-Lun Yeh, Ming-Lung Yu, Shu-Chi Wang   +7 more
doaj   +1 more source