Results 51 to 60 of about 3,063,795 (361)

Tyrosine Kinase Inhibitors Could Be Effective Against Non-small Cell Lung Cancer Brain Metastases Harboring Uncommon EGFR Mutations

Frontiers in Oncology, 2020
Background: The significance of uncommon epidermal growth factor receptor (EGFR) mutations in patients with non-small cell lung cancer (NSCLC) and brain metastasis (BM) remains unclear.
Chunhua Ma, Juncheng Zhang, Juncheng Zhang, Dongjiang Tang, Dongjiang Tang, Xin Ye, Xin Ye, Jing Li, Ning Mu, Zhi Li, Renzhong Liu, Liang Xiang, Liang Xiang, Chuoji Huang, Chuoji Huang, Rong Jiang   +15 more
doaj   +1 more source

Crucial roles of circulating tumor cells in the metastatic cascade and tumor immune escape: biology and clinical translation

Journal for ImmunoTherapy of Cancer, 2022
Cancer-related deaths are mainly caused by metastatic spread of tumor cells from the primary lesion to distant sites via the blood circulation.
Klaus Pantel, Catherine Alix-Panabières
doaj   +1 more source

Beyond blood: Advancing the frontiers of liquid biopsy in oncology and personalized medicine

Cancer Science
Liquid biopsy is emerging as a pivotal tool in precision oncology, offering a noninvasive and comprehensive approach to cancer diagnostics and management.
Ying Bao, Dejing Zhang, Huihui Guo, Wenxue Ma   +3 more
semanticscholar   +1 more source

Exosomes as a new frontier of cancer liquid biopsy

Molecular Cancer, 2022
Liquid biopsy, characterized by minimally invasive detection through biofluids such as blood, saliva, and urine, has emerged as a revolutionary strategy for cancer diagnosis and prognosis prediction.
Dan Yu, Yixin Li, Maoye Wang, Jianmei Gu, Wenrong Xu, Huisi Cai, Xinjian Fang, Xu Zhang   +7 more
semanticscholar   +1 more source

Circulating Genetically Abnormal Cells Add Non-Invasive Diagnosis Value to Discriminate Lung Cancer in Patients With Pulmonary Nodules ≤10 mm

Frontiers in Oncology, 2021
BackgroundLung cancer screening using low-dose computed tomography (LDCT) often leads to unnecessary biopsy because of the low specificity among patients with pulmonary nodules ≤10 mm.
Maosong Ye, Xiaoxuan Zheng, Xiaoxuan Zheng, Xin Ye, Xin Ye, Xin Ye, Juncheng Zhang, Juncheng Zhang, Chuoji Huang, Chuoji Huang, Zilong Liu, Meng Huang, Meng Huang, Xianjun Fan, Xianjun Fan, Yanci Chen, Yanci Chen, Botao Xiao, Jiayuan Sun, Jiayuan Sun, Chunxue Bai   +20 more
doaj   +1 more source

Liquid Biopsy in Neurological Diseases

Cells, 2023
The most recent and non-invasive approach for studying early-stage biomarkers is liquid biopsy. This implies the extraction and analysis of non-solid biological tissues (serum, plasma, saliva, urine, and cerebrospinal fluid) without undergoing invasive ...
S. Malhotra, Mari Carmen Martín Miras, Agustín Pappolla, X. Montalban, M. Comabella   +4 more
semanticscholar   +1 more source

Cell-free DNA methylation as liquid biopsy for the assessment of fibrosis in patients with nonalcoholic steatohepatitis: a gap between innovation and implementation [PDF]

, 2017
The presence of cfDNA in the circulating compartment was demonstrated three decades ago , leading to the emergence of liquid biopsy.However, the implementation of cfDNA methylation as a non-invasive molecular tool for the diagnosis of fibrosis imposes ...
Pirola, Carlos José, Sookoian, Silvia Cristina   +1 more
core   +1 more source

Circulating epithelial cell as viral infection and tissue origin marker in patients with severe COVID-19

The Journal of Liquid Biopsy, 2023
Liquid biopsy (LB) is a minimally invasive procedure that detects biomarkers in body fluids for real-time monitoring of patients. This study developed a new LB approach to analyze Circulating Epithelial Cells (CECs) in Intensive Care Unit (ICU) patients ...
Valeria Denninghoff, María del Carmen Garrido-Navas, María del Pilar Molina-Vallejo, Abel García-Díaz, José Miguel Pérez-Villares, Manuel Colmenero-Ruiz, José Expósito-Hernández, Jose Antonio Lorente, José María Navarro-María, Juan José Díaz-Mochón, Diego de Miguel-Perez, Christian Rolfo, Pedro José Romero-Palacios, Bernardino Alcázar Navarrete, María José Serrano   +14 more
doaj   +1 more source

SERS biosensors for liquid biopsy towards cancer diagnosis by detection of various circulating biomarkers: current progress and perspectives

Nano Convergence
Liquid biopsy has emerged as a promising non-invasive strategy for cancer diagnosis, enabling the detection of various circulating biomarkers, including circulating tumor cells (CTCs), circulating tumor nucleic acids (ctNAs), circulating tumor-derived ...
Nana Lyu, Amin Hassanzadeh-Barforoushi, Laura M Rey Gomez, Wei Zhang, Yuling Wang   +4 more
semanticscholar   +1 more source

The use of heat and chemical penetration enhancers to increase the follicular delivery of erythromycin to the skin [PDF]

, 2019
Copyright © 2019. Published by Elsevier B.V.The effect of heat on the follicular absorption of drugs into the skin has not previously been investigated.
Akomeah, Alberti, Baden, Butcher, Cada, Coldman, Edwards, F. Caserta, FDA, Feldmann, Goh, Higuchi, ICH, Q2(R1), Kim, Kligman, Liu, M.B. Brown, McAuley, McAuley, Minson, Motwani, Motwani, OECD, Oliveira, Otberg, Park, Piazza, Pierard, Rancan, Saar, Santos, Sato, Shergill, Szabo, Teichmann, Toll, Twist, W.J. McAuley, Wood, Wood, Wood, Yarnitsky, Zhang   +42 more
core   +2 more sources