Results 51 to 60 of about 3,006,723 (410)
Molecular Oncology, 2020 Tumor‐associated macrophages have important roles in hepatocellular carcinoma (HCC) initiation and progression. Long noncoding RNAs (lncRNAs) have also been reported to be involved in HCC. In this study, we explored how lncRNA LINC00662 may influence HCC
Xiaohui Tian +7 more
doaj +1 more source
Current Status and Future Perspectives of Liquid Biopsy in Small Cell Lung Cancer
Biomedicines, 2021 Approximately 19% of all cancer-related deaths are due to lung cancer, which is the leading cause of mortality worldwide. Small cell lung cancer (SCLC) affects approximately 15% of patients diagnosed with lung cancer.
Patricia Mondelo-Macía +6 more
doaj +1 more source
Development of a multivariable risk model integrating urinary cell DNA methylation and cell-free RNA data for the detection of significant prostate cancer [PDF]
, 2020 Background: Prostate cancer exhibits severe clinical heterogeneity and there is a critical need for clinically implementable tools able to precisely and noninvasively identify patients that can either be safely removed from treatment pathways or those ...
Bapat, Bharati +11 more
core +1 more source
Frontiers in Cell and Developmental Biology, 2023 Metastatic progression is the deadliest feature of cancer. Cancer cell growth, invasion, intravasation, circulation, arrest/adhesion and extravasation require specific mechanical properties to allow cell survival and the completion of the metastatic ...
Keerthi Kurma +5 more
doaj +1 more source
Advances in Liquid Biopsy Technology and Implications for Pancreatic Cancer
International Journal of Molecular Sciences, 2023 Pancreatic cancer is a highly aggressive malignancy with a climbing incidence. The majority of cases are detected late, with incurable locally advanced or metastatic disease.
A. Raufi +4 more
semanticscholar +1 more source
Transient disappearance of RAS mutant clones in plasma: A counterintuitive clinical use of EGFR inhibitors in RAS mutant metastatic colorectal cancer [PDF]
, 2019 Genomic studies performed through liquid biopsies widely elucidated the evolutionary trajectory of RAS mutant clones under the selective pressure of EGFR inhibitors in patients with wild type RAS primary colorectal tumors. Similarly, the disappearance of
Belardinilli, Francesca +9 more
core +1 more source
Frontiers in Public Health, 2023 ObjectivesMaintenance therapy with capecitabine after induction chemotherapy for patients with newly diagnosed metastatic nasopharyngeal carcinoma (mNPC) has been confirmed to be effective.
Jiaqi Han +5 more
doaj +1 more source
Metabolomic Characterization of Human Model of Liver Rejection Identifies Aberrancies Linked to Cyclooxygenase (COX) and Nitric Oxide Synthase (NOS) [PDF]
, 2019 BACKGROUND Acute liver rejection (ALR), a significant complication of liver transplantation, burdens patients, healthcare payers, and the healthcare providers due to an increase in morbidity, cost, and resources.
Bettcher, Lisa +11 more
core +1 more source
Leukemia, 2023 In the present study, we screened 84 Follicular Lymphoma patients for somatic mutations suitable as liquid biopsy MRD biomarkers using a targeted next-generation sequencing (NGS) panel. We found trackable mutations in 95% of the lymph node samples and 80%
A. Jiménez-Ubieto +27 more
semanticscholar +1 more source
Liquid Biopsy and Colorectal Cancer. [PDF]
South Asian J CancerAbstractThe majority of patients with colorectal cancer (CRC) will ultimately develop metastasis. Identifying specific molecular characteristics in them can help optimize their management in a personalized manner. This requires a noninvasive method for frequent sampling.
Aggarwal S +11 more
europepmc +4 more sources