Results 71 to 80 of about 3,006,723 (410)

Evaluation of a novel saliva-based epidermal growth factor receptor mutation detection for lung cancer: A pilot study. [PDF]

, 2016
BackgroundThis article describes a pilot study evaluating a novel liquid biopsy system for non-small cell lung cancer (NSCLC) patients. The electric field-induced release and measurement (EFIRM) method utilizes an electrochemical biosensor for detecting ...
Akin, David, Dong, Gaochao, Dong, Jingsi, Feng, Ziding, Li, Canjun, Li, Yin, Liang, Hao, Pu, Dan, Qiao, Youlin, Qin, Changlong, Qiu, Xiaoming, Sun, Tong, Tang, Xiaojun, Wan, Huajing, Wang, Xi, Wei, Fang, Wong, David TW, Xu, Lin, Yan, QingXiang, Zhang, Wenbiao, Zhen, Yan, Zhou, Qinghua, Zhu, Daxing   +22 more
core   +1 more source

Recommendations for the Equitable and Widespread Implementation of Liquid Biopsy for Cancer Care

JCO Precision Oncology
Liquid biopsies—tests that detect circulating tumor cellular components in the bloodstream—have the potential to transform cancer by reducing health inequities in screening, diagnostics, and monitoring.
Phillip G Febbo, Mina Allo, Emma Alme, G. Cuyun Carter, R. Dumanois, Alessia Essig, Estevan P. Kiernan, Caitlin B Kubler, Nikki Martin, Medeea C Popescu, Lauren C Leiman   +10 more
semanticscholar   +1 more source

Metastatic Melanoma: Liquid Biopsy as a New Precision Medicine Approach

International Journal of Molecular Sciences, 2023
Precision medicine has driven a major change in the treatment of many forms of cancer. The discovery that each patient is different and each tumor mass has its own characteristics has shifted the focus of basic and clinical research to the singular ...
E. Ricciardi, E. Giordani, Giovanna Ziccheddu, I. Falcone, P. Giacomini, M. Fanciulli, M. Russillo, Marianna Cerro, G. Ciliberto, A. Morrone, A. Guerrisi, F. Valenti   +11 more
semanticscholar   +1 more source

Liquid Biopsy in Oral Cancer [PDF]

International Journal of Molecular Sciences, 2018
Oral cancer is one of the most prevalent forms of cancer worldwide. Carcinogenesis is a complex process, in which heterogeneity plays an important role in the development and progression of the disease. This review provides an overview of the current biological and clinical significance of circulating tumour cells (CTCs), circulating tumour DNA (ctDNA),
Óscar Rapado-González, María Mercedes Suárez-Cunqueiro, María Mercedes Suárez-Cunqueiro, Rafael López-López, Laura Muinelo-Romay, Jose-Luis Lopez-Cedrun, Fatima Lousada-Fernandez   +6 more
openaire   +3 more sources

Circulating Genetically Abnormal Cells Add Non-Invasive Diagnosis Value to Discriminate Lung Cancer in Patients With Pulmonary Nodules ≤10 mm

Frontiers in Oncology, 2021
BackgroundLung cancer screening using low-dose computed tomography (LDCT) often leads to unnecessary biopsy because of the low specificity among patients with pulmonary nodules ≤10 mm.
Maosong Ye, Xiaoxuan Zheng, Xiaoxuan Zheng, Xin Ye, Xin Ye, Xin Ye, Juncheng Zhang, Juncheng Zhang, Chuoji Huang, Chuoji Huang, Zilong Liu, Meng Huang, Meng Huang, Xianjun Fan, Xianjun Fan, Yanci Chen, Yanci Chen, Botao Xiao, Jiayuan Sun, Jiayuan Sun, Chunxue Bai   +20 more
doaj   +1 more source

A pilot study evaluating concordance between blood-based and patient-matched tumor molecular testing within pancreatic cancer patients participating in the Know Your Tumor (KYT) initiative [PDF]

, 2016
Recent improvements in next-generation sequencing (NGS) technology have enabled detection of biomarkers in cell-free DNA in blood and may ultimately replace invasive tissue biopsies.
Aberra, Metasebia, Bender, R. Joseph, Brody, Jonathan, Chung, Vincent, Heartwell, Craig, Hendifar, Andrew, Hoos, William A., Madhavan, Subha, Mason, Kimberly, Matrisian, Lynn M., Mikhail, Sam, Petricoin, Emanuel, III, Picozzi, Vincent, Pishvaian, Michael J., Rahib, Lola, Varieur, Katelyn   +15 more
core   +2 more sources

Recent advances in droplet‐based microfluidics in liquid biopsy for cancer diagnosis

Droplet
Liquid biopsy, a noninvasive technique to obtain tumor information from body fluids, is an emerging technology for cancer diagnosis, prognosis, and monitoring, providing crucial support for the realization of precision medicine.
Jing Shi, Yu Zhang, Yadi Fan, Yi Liu, Mo Yang   +4 more
semanticscholar   +1 more source

Liquid biopsies for bladder cancer [PDF]

Translational Andrology and Urology, 2017
The development of accurate urinary biomarkers for the non-invasive detection of urothelial bladder cancer (UBC) could transform patient pathways by reducing reliance on cystoscopy, and the identification of highly prognostic (or even predictive) biomarkers could better guide patient management.
Richard T. Bryan, Douglas G. Ward
openaire   +3 more sources

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

Molecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever, Renske D. M. Steenbergen   +1 more
wiley   +1 more source

Targeting Drp1 inhibits ESCC progression via the ROS-PGC1-α-Nrf1/2 pathway

Journal of Translational Medicine
Background Esophageal squamous cell carcinoma (ESCC) ranks among the most prevalent malignancies of the digestive tract. Due to the absence of obvious symptoms in patients with early-stage ESCC, most cases are diagnosed at advanced stages, highlighting ...
Zhixiong Jiang, Yating Yang, Jinchi Zhou, Xin Li, Qingqing Meng, Xiangyi Yu, Yaxin Xue, Mengyu Li, Yichen Cai, Pengchun Han, Mingjun Jiang, Huizhen Wang, Congrong Liu, Jing Zhao, Lixin Wan, Dengke Bao   +15 more
doaj   +1 more source