Results 61 to 70 of about 4,935,227 (284)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Inflation targeting and the liquidity trap [PDF]
, 2001 This paper considers whether "liquidity trap" issues have important bearing on the desirability of inflation targeting as a strategy for monetary policy. From a theoretical perspective, it has been suggested that "expectation trap" and "indeterminacy" dangers are created by variants of inflation targeting, the latter when forecasts of future inflation ...
openaire +4 more sources
Development of a 10 MeV Ultra-Compact Cyclotron for Short-Lived Isotope Production
Journal of IsotopesTo address the heavy reliance on imported medical cyclotrons in China，the China Institute of Atomic Energy has independently developed a 10 MeV ultra-compact cyclotron，aiming at achieving localized and low-cost production of medical radioisotopes.
He ZHANG +24 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Inflation targeting and liquidity traps under endogenous credibility [PDF]
Journal of Monetary Economics, 2019 Policy implications are derived for an inflation-targeting central bank, whose credibility is endogenous and depends on its past ability to achieve its targets. This is done in a New Keynesian framework with heterogeneous and boundedly rational expectations.
Hommes, Cars, Lustenhouwer, Joep
openaire +4 more sources
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Scientific Reports, 2021 The interaction between an argon plasma jet excited using microsecond duration voltage pulses and a liquid target was examined using Thomson scattering to quantify the temporal evolution of the electron density and temperature.
Elmar Slikboer, James Walsh
doaj +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Liquid-Core Hydrogel Optical Fiber Fluorescence Probes
, 2022 This paper first reports a liquid-core hydrogel optical fiber fluorescence probe. It is composed of a liquid core, a high-refractive-index hydrogel fiber core, and a low-refractive-index hydrogel fiber cladding, which is completely different from many ...
Ting Liu (45625) +4 more
core +1 more source