Results 61 to 70 of about 7,838 (234)

Tirzepatide Improved Health-Related Quality of Life Compared with Insulin Lispro in Basal Insulin-Treated Adults with Type 2 Diabetes and Inadequate Glycaemic Control: A Randomised Controlled Phase 3b Trial (SURPASS-6)

Diabetes Therapy
Patients with type 2 diabetes (T2D) who require intensification of basal insulin therapy need treatment options that can improve their health-related quality of life (HRQoL) and translate into better outcomes.
K. Boye, J. Poon, L. F. Landó, Hélène Sapin, Ruth Huh, Mianbo Wang, Suzanne Williamson, H. Patel   +7 more
semanticscholar   +1 more source

Pharmacokinetics and Glucodynamics of Ultra Rapid Lispro (URLi) versus Humalog® (Lispro) in Younger Adults and Elderly Patients with Type 1 Diabetes Mellitus: A Randomised Controlled Trial

Clinical Pharmacokinetics, 2020
Ultra rapid lispro (URLi) is a novel insulin lispro formulation developed to more closely match physiological insulin secretion and improve postprandial glucose control. This study compared the pharmacokinetics, glucodynamics, safety, and tolerability of
H. Linnebjerg, Qianyi Zhang, E. Labell, M. Dellva, D. Coutant, U. Hövelmann, L. Plum-Mörschel, T. Herbrand, J. Leohr   +8 more
semanticscholar   +1 more source

A study of changes in insulin requirements related to the menstrual cycle in Japanese women with type 1 diabetes using the advanced hybrid closed‐loop system

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Aims/Introduction In type 1 diabetes (T1D), insulin requirements and glycemic control may vary across the menstrual cycle. We examined phase‐related differences in insulin requirements, glycemic metrics, and recorded carbohydrate amounts in women using an advanced hybrid closed‐loop (AHCL) system and their associations with menstrual symptoms ...
Eri Takagi, Hideyoshi Kaga, Ryoki Mori, Shohei Fujikawa, Haruki Nagashima, Toshiki Kogai, Mami Koshibu, Junko Sato, Yuya Nishida, Fuki Ikeda, Yoshifumi Tamura, Hirotaka Watada   +11 more
wiley   +1 more source

Hybrid Closed-Loop Control with Ultrarapid Lispro Compared with Standard Insulin Aspart and Faster Insulin Aspart: An In Silico Study

Journal of Diabetes Science and Technology, 2021
Objective: There is room for improvement in the performance of closed-loop regulation algorithms during the prandial period. This in silico study evaluated the efficiency and safety of ultrarapid lispro insulin using the Diabeloop DBLG1® algorithm ...
S. Lachal, Yousra Tourki, S. Franc, E. Huneker, G. Charpentier, P. Benhamou   +5 more
semanticscholar   +1 more source

Reduced frequency of severe hypoglycemia and coma in well-controlled IDDM patients treated with insulin lispro. The Benelux-UK Insulin Lispro Study Group

, 1997
OBJECTIVE: Several studies have suggested that use of the short-acting insulin analog, insulin lispro, in multiple injection therapy may reduce the risk of hypoglycemia in comparison with regular insulin.
Symanowski, S., Rottiers, R., Holleman, F., Rees, A., Schmitt, H., Anderson, J. H.   +5 more
core   +1 more source

Lipoatrofia związana z podażą szybko działających analogów insuliny u młodych pacjentów chorujących na cukrzycę typu 1 [PDF]

Pediatric Endocrinology, Diabetes and Metabolism, 2008
Lipoatrofia, jako skórne powikłanie występujące u chorych na cukrzycę, przestała być problemem klinicznym po wprowadzeniu do leczenia ludzkiej insuliny.
Agata Skórka, Agnieszka Szypowska, Ewa Pańkowska   +2 more
doaj  

Insulin Efsitora Demonstrates Similar Efficacy and Safety Profiles to Insulin Icodec in Insulin‐Experienced Individuals With Type 2 Diabetes Mellitus: Matching‐Adjusted Indirect Comparisons of QWINT‐3 Versus ONWARDS 2, and QWINT‐4 Versus ONWARDS 4

Diabetes, Obesity and Metabolism, Volume 28, Issue 11, Page 10725-10735, November 2026.
ABSTRACT Aims To conduct indirect treatment comparisons (ITCs) of insulin efsitora alfa (efsitora) versus insulin icodec (icodec) in insulin‐experienced individuals with Type 2 Diabetes Mellitus. Methods Efficacy, safety and patient reported outcomes were compared via matching‐adjusted ITCs using results from randomised controlled trials: QWINT‐3 ...
Harpreet S. Bajaj, Marvin Fischer, Michael B. Davidson, Abdul M. Tarafder, Christopher J. Michaels, Rachel H. Tao, Alex Pashley, Jess Amis, Josefine Redig   +8 more
wiley   +1 more source

Improved postprandial glucose control with ultra rapid lispro versus lispro with continuous subcutaneous insulin infusion in type 1 diabetes: PRONTO‐Pump‐2

Diabetes, obesity and metabolism, 2020
To evaluate the efficacy and safety of ultra rapid lispro (URLi) versus lispro (Humalog®) in people with type 1 diabetes on continuous subcutaneous insulin infusion (CSII).
M. Warren, B. Bode, Ik-Cho Jang, Rong Liu, J. Tobian, T. Hardy, Farai Chigutsa, M. Phillip, Barry S. Horowitz, D. Ignaut   +9 more
semanticscholar   +1 more source

Dorsal Pancreatic Agenesis Associated With New‐Onset Diabetes Mellitus and Acute Pancreatitis in an 18‐Year‐Old Man: A Case Report

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Dorsal pancreatic agenesis (DPA) is a rare congenital disorder resulting from failure of development of the dorsal pancreatic bud. Complete DPA implies absence of the pancreatic neck, body, and tail and can be associated with both diabetes mellitus and pancreatitis. The patient was an 18‐year‐old man admitted with a history of epigastric pain,
Mugheesa Rab, Muhammad Hassaan Javaid, Rabia Narmeen Numani, Fozia Khanam, Muddassir Khalid, Fred Segawa   +5 more
wiley   +1 more source

Ultra‐Fast Insulin–Pramlintide Co‐Formulation for Improved Glucose Management in Diabetic Rats

Advanced Science, 2021
Dual‐hormone replacement therapy with insulin and amylin in patients with type 1 diabetes has the potential to improve glucose management. Unfortunately, currently available formulations require burdensome separate injections at mealtimes and have ...
Caitlin L. Maikawa, Peyton C. Chen, Eric T. Vuong, Leslee T. Nguyen, Joseph L. Mann, Andrea I. d'Aquino, Rayhan A. Lal, David M. Maahs, Bruce A. Buckingham, Eric A. Appel   +9 more
doaj   +1 more source