Results 41 to 50 of about 11,022 (215)
Structures of human dynein in complex with the lissencephaly 1 protein, LIS1
eLife, 2023 The lissencephaly 1 protein, LIS1, is mutated in type-1 lissencephaly and is a key regulator of cytoplasmic dynein-1. At a molecular level, current models propose that LIS1 activates dynein by relieving its autoinhibited form.
Janice M Reimer +3 more
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Identification of Alternative Transcription Start Sites that Generate Neuron-Specific nhsl1b Isoform that Regulates Neuron Migration [PDF]
, 2020 Identification of Alternative Transcription Start Sites that Generate Neuron-Specific nhsl1b Isoform that Regulates Neuron Migration Abanoub Bector, Depts. of Biology and Chemistry, with Dr. Sarah Golding, Dept.
Bector, Abanoub
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Genotype-phenotype correlation in neuronal migration disorders and cortical dysplasias
Frontiers in Neuroscience, 2015 Neuronal migration disorders are human (or animal) diseases that result from a disruption in the normal movement of neurons from their original birth site to their final destination during early development. As a consequence, the neurons remain somewhere
Mitsuhiro eKato, Mitsuhiro eKato
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Microtubules gate tau condensation to spatially regulate microtubule functions. [PDF]
, 2019 Tau is an abundant microtubule-associated protein in neurons. Tau aggregation into insoluble fibrils is a hallmark of Alzheimer's disease and other types of dementia1, yet the physiological state of tau molecules within cells remains unclear.
A Ettinger +47 more
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Advanced Healthcare Materials, EarlyView.Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram +10 more
wiley +1 more source
Lissencephaly and cerebellar hypoplasia in a goat
Ciência Rural, 2013 A case of lissencephaly and cerebellar hypoplasia was observed in a 30-day-old goat. The goat presented with sternal recumbence, absence of a menace response, intention tremors, ataxia, and nystagmus.
José Rômulo Soares dos Santos +6 more
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Newborn with ambigous genitalia and refractory convulsions: Case report of XLAG syndrome
Journal of Family Medicine and Primary Care, 2020 X-linked lissencephaly, absent corpus callosum, and epilepsy of neonatal onset with ambiguous genitalia are the classical features of XLAG syndrome and as of now very few cases have been reported in the literature.
Anjali Verma +3 more
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Brain Pathways in LIS1-Associated Lissencephaly Revealed by Diffusion MRI Tractography
Brain Sciences, 2023 Lissencephaly (LIS) is a rare neurodevelopmental disorder with severe symptoms caused by abnormal neuronal migration during cortical development. It is caused by both genetic and non-genetic factors.
Alpen Ortug +5 more
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, 2017 We consider the mechanisms by which folds, or sulci (troughs) and gyri (crests), develop in the brain. This feature, common to many gyrencephalic species including humans, has attracted recent attention from soft matter physicists.
Garikipati, K., Verner, S. N.
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Construction of 3D in vitro models by bioprinting human pluripotent stem cells: Challenges and opportunities [PDF]
, 2019 Three-dimensional (3D) printing of biological material, or 3D bioprinting, is a rapidly expanding field with interesting applications in tissue engineering and regenerative medicine. Bioprinters use cells and biocompatible materials as an ink (bioink) to
Rosa, Alessandro, Salaris, Federico
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