Results 31 to 40 of about 162 (155)

The First Baby Born After Polygenic Embryo Screening

open access: yesVoices in Bioethics, 2022
INTRODUCTION The possibility of using genetic technologies to engineer the perfect baby has long haunted the public imagination. While some techno-utopians have openly advocated for human genetic enhancement, many critics have warned that advances in ...
Kalina Kamenova, Hazar Haidar
doaj  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Translation testing and evaluation: A study on methods and needs

open access: yesTranslation and Interpreting : the International Journal of Translation and Interpreting Research, 2014
The use of technology in the translation process has already become a common practice. Translation evaluation in most training programs in Turkey, however, seems to ignore the place of technology since exams are taken using printed resources only.
Mehmet Şahin, Nilgün Dungan
doaj  

Evaluating literary translation by large language models: a multidimensional quality assessment of Shen Congwen’s Border Town

open access: yesHumanities & Social Sciences Communications
Large language models (LLMs) have exhibited remarkable abilities in understanding and generating human language, which is applied in transferring languages. However, the translation of literary works presents unique challenges. The translation quality of
Wei Yang, Mingxing Yang
doaj   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

The Role of the Translator in the Digital Age

open access: yesLinguaculture
The field of translation has been fundamentally changed by the fast development of artificial intelligence (AI), which also begs questions regarding the future function of human translators.
Corina Dobrotă
doaj   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Evaluating Uighur literary translation: A comparative study of ChatGPT, Google Translate, and Bing Translator.

open access: yesPLoS ONE
This study compares generative artificial intelligence (GenAI) and neural machine translation (NMT) systems in translating Uighur literary text (قۇتادغۇ بىلىك)into English.
Qiufen Wang
doaj   +1 more source

CULTURAL SENSITIVITY IN AI TRANSLATION OF CHINESE LANGUAGE: EVALUATING AI’S CAPABILITY TO GRASP CULTURALLY RICH TEXTS

open access: yesStudia Universitatis Babeş-Bolyai. Philologia
Cultural Sensitivity in AI Translation of Chinese Language: Evaluating AI’s Capability to Grasp Culturally Rich Texts. The widespread adoption of Artificial Intelligence (AI) in translation has fundamentally reshaped global communication by enhancing ...
Iulia Elena CÎNDEA, Jiong WANG
doaj   +1 more source

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