Results 51 to 60 of about 1,078,886 (299)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Strange Interferences : Modernism and Conservativism vs. Avant-Garde, Hungary, 1910’s [PDF]
, 2012 It is a highly peculiar phenomenon in Hungarian – and perhaps in East and Central European – literature of the early 20th century that Avant-Garde tendencies started to gain some (weak) position parallel with the first wave of Modernism, and when they
Kálmán C., György
core +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
PLoS ONE, 2018 Quality circles or peer review groups, and similar structured small groups of 6-12 health care professionals meet regularly across Europe to reflect on and improve their standard practice.
Adrian Rohrbasser +4 more
doaj +1 more source
Global school relationships. School linking and future challenges [PDF]
, 2007 The process of School Linking has attained a raised profile in UK Development Education circles in recent years. This paper reviews recent literature ans issues.
Leonard, Alison
core +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Why the fuss over Brown’s The Da Vinci code? The dynamism of 'icons' and the in/stability of meaning
Koers : Bulletin for Christian Scholarship, 2009 Dan Brown’s book, “The Da Vinci code” (2003) and the sub-sequent motion picture by the same title (2006), have created a considerable stir within, but not limited to, Christian circles.
C. Lombaard
doaj +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Exploring Life Experiences through Literature Circles
HOW, 2016 This article informs on some insights about pupils' reading engagements through literature circles and the way those circles can be implemented in the classrooms.
Johana Mendez Sarmiento +1 more
doaj
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source