Results 61 to 70 of about 6,827,876 (298)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Romantic Psyche and Psychoanalysis [PDF]

open access: yes, 2008
This volume of Romantic Circles Praxis Series includes an editor's introduction by Joel Faflak, essays by Ildiko Csengei, Matt ffytche, Mary Jacobus, Julie Carlson, Tilottama Rajan, and Ross Woodman.  "Romantic Psyche and Psychoanalysis" offers a ...
Romantic Circles
core   +1 more source

Conceptualising success and failure in circles of support and accountability [PDF]

open access: yes, 2020
This paper presents an exploration into success and failure in Circles of Support and Accountability (Circles). Successes in Circles are commonly reported in the literature whilst failure, for reasons relating to funding of the intervention, are often ...
Michelle Dwerryhouse   +7 more
core   +1 more source

Exploring Life Experiences through Literature Circles

open access: yesHOW, 2016
This article informs on some insights about pupils' reading engagements through literature circles and the way those circles can be implemented in the classrooms.
Johana Mendez Sarmiento   +1 more
doaj  

Is Euler’s circle a symbol or an icon?

open access: yesSign Systems Studies, 2015
The most familiar scheme of diagrams used in logic is known as Euler’s circles. It is named after the mathematician Leonhard Euler who popularized it in his Letters to a German Princess (1768).
Amirouche Moktefi
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Literature Circles Strategy as a Support for EFL Students’ Reading Comprehension Skills and Motivation

open access: yesمجلة الآداب
The current study aims to explore the impact of using literature circles strategy on supporting EFL college students ‘reading comprehension skills and motivation towards reading.
Zainab Jawad
doaj   +1 more source

LET’S TALK AND TOLERATE: STRENGTHENING STUDENTS CULTURAL AWARENESS THROUGH LITERATURE CIRCLES

open access: yesIndonesian Journal of Applied Linguistics, 2014
: Putting more attention on teaching language skills, the use of literature in EFL classrooms is often abandoned. While essentially, exploiting literary texts in some advanced EFL courses, serves a variety of purposes, dedicated to encourage interactive ...
Nicke Yunita Moecharam   +1 more
doaj   +1 more source

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