Results 21 to 30 of about 1,978,943 (206)
Prevalent levels of RSV serum neutralizing antibodies in healthy adults outside the RSV-season
Human Vaccines & Immunotherapeutics, 2020 One of the main challenges in early clinical research with respiratory syncytial virus (RSV) live-attenuated vaccines (LAVs) is to assess immunogenicity in healthy adults.
Johan L. Van Der Plas +6 more
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Poultry Science, 2022 : Repeated serial in vitro passage of Histomonas meleagridis, the etiological agent of histomoniasis (blackhead) of turkeys, was demonstrated to markedly achieve attenuation and reduction of virulence as compared to the original wild-type isolate.
L.C. Beer +7 more
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MicroRNA-Attenuated Virus Vaccines
Non-Coding RNA, 2018 Live-attenuated vaccines are the most effective way to establish robust, long-lasting immunity against viruses. However, the possibility of reversion to wild type replication and pathogenicity raises concerns over the safety of these vaccines. The use of
Elizabeth J. Fay, Ryan A. Langlois
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Radiation-attenuated schistosome vaccination--a brief historical perspective. [PDF]
, 2009 The high level of protection which can be induced by vaccination of a range of hosts, from rodents to primates, with live radiation-attenuated schistosome larvae offers great promise for development of a human schistosome vaccine.
Bickle, QD, Q. D. BICKLE
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Virology Journal, 2012 Background H5N1 highly pathogenic avian influenza virus (HPAIV) is continuously circulating in many Asian countries and threatening poultry industry and human population.
Zhang Wenting +4 more
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Vaccines, 2023 Middle East respiratory syndrome coronavirus (MERS-CoV) causes severe diseases in humans. Camels act as intermediate hosts for MERS-CoV. Currently, no licensed vaccine is available for this virus.
Heejeong Seo, Yunyueng Jang, Dongmi Kwak
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EBioMedicine, 2020 Background: Live attenuated vaccines (LAVs) can mimic natural infection and have advantages to stimulate a robust and sustained immune response as well as to confer long-term protection.
Ya-Nan Zhang +7 more
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, 2023 Mosquito-transmitted chikungunya virus (CHIKV) is the causal pathogen of CHIKV disease and is responsible for global epidemics of arthritic disease. CHIKV infection can lead to severe chronic and debilitating arthralgia, significantly impacting patient ...
Abeyratne, E +21 more
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An overview of VaxchoraTM, a live attenuated oral cholera vaccine
Human Vaccines & Immunotherapeutics, 2020 Cholera remains a public health threat among the least privileged populations and regions affected by conflicts and natural disasters. Together with Water, Sanitation and Hygiene practices, use of oral cholera vaccines (OCVs) is a key tool to prevent ...
Tarun Saluja +4 more
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Delivery of spike-RBD by bacterial type three secretion system for SARS-CoV-2 vaccine development
Frontiers in Immunology, 2023 COVID-19 pandemic continues to spread throughout the world with an urgent demand for a safe and protective vaccine to effectuate herd protection and control the spread of SARS-CoV-2. Here, we report the development of a bacterial vector COVID-19 vaccine (
Yuchen Zhou +16 more
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