Results 61 to 70 of about 1,978,943 (206)

Attenuation mechanism of Brucella melitensis M5-10, implications for vaccine development and differential diagnosis [PDF]

open access: yesFrontiers of Agricultural Science and Engineering, 2014
Brucellosis is a worldwide zoonosis. Vaccination is the most efficient means to prevent and control brucellosis. The current licensed attenuated vaccines for animal use were developed by sequential passage in non-natural hosts that decreased virulence in
Yuanqiang ZHENG,Yanchun SHI,Chang AN,Ruisheng LI,Dongjun LIU,Yuehua KE,Kairong MAO,Mingjuan YANG,Zeliang CHEN,Shorgan BOU
doaj   +1 more source

Manufacture of a Stable Lyophilized Formulation of the Live Attenuated Pertussis Vaccine BPZE1

open access: yesVaccines, 2020
Current pertussis vaccines protect against disease, but not against colonization by and transmission of Bordetella pertussis, whereas natural infection protects against both.
Marcel Thalen   +7 more
doaj   +1 more source

Postfazione a: Redazione de Il Bo Live, a cura di, Per un’unica conoscenza. Pietro Greco e Il Bo Live

open access: yes, 2022
Postfazione alla raccolta degli scritti di Pietro Greco apparsi sul web magazine Il Bo ...
T. Pievani
core  

A randomised trial evaluating the safety and immunogenicity of the novel single oral dose typhoid vaccine M01ZH09 in healthy Vietnamese children. [PDF]

open access: yes, 2010
BACKGROUND: The emergence of drug resistant typhoid fever is a major public health problem, especially in Asia. An oral single dose typhoid vaccine would have major advantages.
Schultsz, C   +162 more
core   +2 more sources

Rotavirus in developing countries: molecular diversity, epidemiological insights, and strategies for effective vaccination

open access: yesFrontiers in Microbiology
Rotavirus (RV) causes the loss of numerous children’s lives worldwide each year, and this burden is particularly heavy in low- and lower-middle-income countries where access to healthcare is limited. RV epidemiology exhibits a diverse range of genotypes,
Asma Sadiq, Jadoon Khan
doaj   +1 more source

Deletion of an immune evasion gene, steD, from a live Salmonella enterica serovar Typhimurium vaccine improves vaccine responses in aged mice

open access: yesFrontiers in Immunology
IntroductionNon-typhoidal Salmonella (NTS) generally causes self-limiting gastroenteritis. However, older adults (≥65 years) can experience more severe outcomes from NTS infection. We have previously shown that a live attenuated S.
Jessica C. Allen   +9 more
doaj   +1 more source

Live attenuated oral cholera vaccines

open access: yesExpert Review of Vaccines, 2006
Live, orally administered, attenuated vaccine strains of Vibrio cholerae have many theoretical advantages over killed vaccines. A single oral inoculation could result in intestinal colonization and rapid immune responses, obviating the need for repetitive dosing. Live V.
Edward T, Ryan   +2 more
openaire   +2 more sources

Genotype II Live-Attenuated ASFV Vaccine Strains Unable to Completely Protect Pigs against the Emerging Recombinant ASFV Genotype I/II Strain in Vietnam

open access: yesVaccines
Background: African swine fever virus (ASFV) continues to spread globally, causing severe economic losses to pig farmers. Vietnam licensed two live attenuated vaccines based on the ASFV strains ASFV-G-ΔI177L and ASFV-G-ΔMGF to control the ongoing ASF ...
Nguyen Van Diep   +10 more
doaj   +1 more source

Live-attenuated bacterial vectors: Tools for vaccine and therapeutic agent delivery

open access: yes, 2015
Genetically attenuated microorganisms, including pathogenic and commensal bacteria, can be engineered to carry and deliver heterologous antigens to elicit host immunity against both the vector as well as the pathogen from which the donor gene is derived.
Ivan Lin (11230175)   +2 more
core  

Envelope Exchange for the Generation of Live-Attenuated Arenavirus Vaccines. [PDF]

open access: yes, 2006
Arenaviruses such as Lassa fever virus cause significant mortality in endemic areas and represent potential bioterrorist weapons. The occurrence of arenaviral hemorrhagic fevers is largely confined to Third World countries with a limited medical ...
Horvath Edit   +17 more
core   +1 more source

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